4B Part 2

Question 1

resins bind bile acids in the intestinal lumen -this leads to what two things

Answer 1

• decrease emulsification of dietary fat
• prevention of bile acid reabsorption, this causes the liver the increases production of bile acids, using hepatic cholesterol to do so

Question 2

by using resins, plasma LDL level can be reduced by up to _____ with maximal doses

Answer 2

30%

Question 3

what effect to resins have on HDL and triglyceride

Answer 3

little to no effect

Question 4

what are the adverse effects of bile acid binding resins

Answer 4

• constipation
• bloating/abdominal distention/pain
• flatulance
• nausea
• vomiting
• dyspepsia

Question 5

what things can help relieve symptoms of bile acid binding resins

Answer 5

• slow dose titration

- increased of dietary fiber (for bloating)`

Question 6

what can be done to avoid drug- drug interaction with bile acid binding resins

Answer 6

take the resin a few hours after taking medication

Question 7

calcium absorption occurs in the ______ and _______ and is primarily regulated by ________ ___ which stimulates synthesis of CA+2 binding proeins called calbumidins in enterocytes

Answer 7

duodumum, jejunum, Vitamin D3

Question 8

what are the fat soluble vitamins

Answer 8

A,D,E, and K

Question 9

how are most water soluble vitamins absorbed

Answer 9

simple diffusion

Question 10

what water soluble vitamins require Inrinsic factor to be absorbed

Answer 10

Vit. B12, Cobalamin; CBL

Question 11

____ cells abosrb _______ complexes across the brush border

Answer 11

Ilial, IF-Vitamin B12

Question 12

what can cause a IF deficiency

Answer 12

Atrophy of the gastric mucosa

Question 13

how long does it take chyme to move the the entire SI

Answer 13

3-5 hours