4B Diversity classification and variation Flashcards
what are gametes
sperm cells in males and the egg cells in females
when gametes join together in fertilisation what do they form
zygote, which divides and develops into a new organism
what diploid number to normal body cells have
2n
meaning each cell has two of each chromosome one from mum and one from dad
what is gametes haploid number
n
one copy of each chromosome
what happens at fertilisation
a haploid sperm fuses with a haploid egg making cell with normal diploid number
half chromosomes from mum (egg) and half from dad(sperm)
how is genetic diversity increased within species by fertilisation
fertilisation is random (any sperm with any egg(
so produces zygotes with different combinations of chromosomes to both parents (mixes genetic material)
where does meiosis take place
reproductive organs
how do cells start and finish via meiosis
start as diploid finish as haploids (have half the chromosomes)
6 steps of meiosis
1) before meiosis-DNA unravels & replicates so there are two copies of each chromosomes called chromatids
2) DNA condenses forming double armed chromosomes, made from two sister chromatids - sister chromatids joined by centromere
3) meiosis I- chromosomes orange into homologous pairs
4) homologous pairs separated halting chromosome number
5) meiosis II- pairs of sister chromosatids which make up each chromosome are separated (centromere divides)
6) four haploid cells(gametes) that are genetically different are formed
how many homologous pairs do human have
23
46 single chromosomes
during meiosis I what happens which causes the chromatids to have a different combination of alleles
homologous pairs of chromosomes pair up together
chromatids twist around each other and parts of the chromatids swap over
now chromatids still have same genes but different combination of alleles
how does the crossing over of chromatids during meiosis I produce cells which are genetically different
causes each of the four daughter cells formed have chromatids with different alleles
increases genetic variation
how does the independent segregation of chromosomes cause cells to be produced which are genetically different
when homologous pairs are separated (meiosis I) its random which chromosome from the pair ends up with which daughter cell
so 4 daughter cells have different combinations of those maternal and paternal chromosomes
this shuffling causes genetic variation in potential offspring
difference between meiosis and mitosis
1)mitosis produces cells w/same no. of chromosomes as parent cells
meiosis produces cells w/half chromosomes as parent cells
2)mitosis daughter cells are genetically identical to each other &parent cells
meiosis daughter cells are genetically different to each other and parent cell
3)mitosis produces two daughter cells
meiosis produces four daughter cells
how are chromosome mutations caused generally
errors in cell division
what is the chromosome mutation non-disjunction
failure of chromosomes to separate properly
what does non-disjunction of chromosome 21 cause
downs syndrome
detail how downs syndrome is caused
person having extra copy of chromosome 21
non disjunction means chromosome 21 fails to separate properly in meiosis so one cell gets an extra copy of chromosome 21 and the other cell gets none
so when the gamete with an extra chromosome fuses with another gamete at fertilisation the zygote will end up with 3 chromosomes 21
what is another mutation
changes to the base sequence of DNA
deletion or substitution
what is deletion mutation
one base is deleted (in DNA)
what is substitution mutation
one base is substituted with another (in dna)
how can a change in dna bases cause a mutation
as order of dna bases determines order of amino acids and therefore the protein which is made,
if the bases change the sequence of amino acids change and therefore a different protein is coded for
why do not all mutations affect the order of amino acids
substitution
as the genetic code is degenerate and more than one dna triplet can code for an amino acid
this mean substitution does not always result in change in amino acid sequence
why does deletion always cause change in amino acid sequence
as when a base is deleted it changes the number of base present - this causes a shift in all the base triplets after it
what are mutagenic agents
things that increase rate of mutations
examples of mutagenic agents
ultraviolet radiation
ionising radiation
some chemicals and viruses
how can gentic diversity within a population be increased
- mutations in DNA
- different alleles introduced into population
what is gene flow
when individuals from another population migrate into them and reproduce -causing genetic diversity increases
what is a genetic bottleneck
an event which causes a big reduction in a population