40: Pulmonary Embolism - Kersenbrock Flashcards

1
Q

exogenous or endogenous material migration to the pulmonary vasculature causing various degrees of obstruction

A

pulmonar embolism

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2
Q

___ % of untreated DVT leads to PE

A

10-30%

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3
Q

patient with recent fracture…

A

fat droplet etiiology of PE

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4
Q

virchow’s triad

A
  • hypercoagulability
  • endothelial damage
  • venous stasis
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5
Q

symptoms of PE

A
  • tachypnea
  • hypoxemia
  • chest or pleuritic pain
  • dyspnea
  • anxiety
  • cough
  • tachycardia
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6
Q

what type of HF can result from PE?

A

right heart failure

  • when the RV can’t genereate enough pressure in systole to push the clot further into the branched vascular bed, it weakens with resultant RHf
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7
Q

what D- dimer level would indicate a PE?

A

d-dimer level is 550 or greater, the sensitivity for presence of PE may be as high as 98%

a negative d-dimer doesn’t rule out PE if they are deemed high or moderate risk

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8
Q

troponin and PE>

A

may be elevated if RV has been stressed

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9
Q

ECG changes with PE

A

sinus tachycarida

-S1Q3T3

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10
Q

what is S1Q3T3?

A

s wave in lead I

q waves in lead III
inverted t waves in lead III

may indicate PE

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11
Q

CXR reveals: a peripheral conical density with the base opposed to the chest wall

A

hamptom hump –> on CXR indicates PE

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12
Q

primary diagnositc method for suspected PE

A

CT angiography CTA

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13
Q

what do you need to check before ordering a CTA?

A

kidney function – get a BMP

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14
Q

pt has renal failure and suspected PE – what imaging can you use?

A

ventialtion-perfusion scan

normal scan can exclude PE but not very sensitive to diagnosis

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15
Q

“gold standard” for PE diagnosis

A

pulmonary arteriography

reserved for pts w/ whom uncertainty remains after CTA

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16
Q

treat stable pt with PE =

A
  • anticoagulation with heparin

- warfarin started at same time as heparin

17
Q

treat hemodynamically unstable pt with PE =

A
  • thrombolytic therapy followed by anticoaglation
18
Q

contraindications for thrombolytics?

A

intracranial bleeds

anything that might break open and bleed

also HTN over 180/100

no preggers

19
Q

how long is anitcoagulation continued post PE?

A

3 months

longer with greater risks

20
Q

clinical suspicion is low and d-dimer is negative =

A

no further testing needed, not a PE

21
Q

CTA and d-dimer are negative/nondiagnostic and suspicion is low =

A

no further testing needed

if suspicion is hgih a leg study should be considered or pulmonary arteriography