4 - Cardiac Cycle Flashcards
SA Node
AV Node
SA - Naturaly pacemaker, determined rate of spontaneous generation of APs
AV - Only pathway which wave of depolarizations reach ventricles–Slows conduction time intentionally
Why does the R/L heart operate simultaneously?
From a functional standpoint, how should we view the heart?
It has a single electrical conduction system
Two separate pumps in-series
Ventricles vs Atria
Ventricles = Thick walled, pump blood (systemic)
Atria = Thin walled, collect returning venous blood, weak primer pump–increases ~ 40% ventricle filling during exercise
What are the implicatiosn of the in-series arrangement of the heart’s pumps?
- Separation of Pulmonar/Systemic Circulation
- Equal volume of blood from R/L sides
- Left heart generates more pressure
How do Cardiac Valves open and close?
Passively
Cardiac Valves: Atrioventricular (AV) Valves
Prevent backglow of blood into the atria during ventricular systole
Two:
- Tricuspid Valve (Right Atrium - Right Ventricle)
- Mitral Valve (Left Atrium - Left Ventricle)
Cardiac Valves: Semilunar Valves
Prevent backflow of blood from aorta and pulmonary arteries into the ventricles during ventricular diastole
Two:
- Aortic Valve (Left Ventricle - Aorta)
- Pulmonary Valve (Right Ventricle - Pulmonary Artery)
**These valves close fast due to higher pressure, and blood flows through at a greater velocity–smaller openings**
What creates the heart sounds audible with a stethoscope?
Closure of Valves
Normal Heart Sounds: First Heart Sound
Atrioventricular Valves - Closure at Onset of Systole
Normal Heart Sounds: Second Heart Sound
Semilunar Valves - Closure at End of Ventricular Systole
What is the cardiac cycle a measure of?
What measures electrical events during this?
What measures Pressure?
What measures volume?
What measures sounds?
One complete sequence of cardiac contraction and relaxation.
Electrocardiography
Pressure recording devices implanted
Echocardiography (volume)
Phonocardiogram
Ventricular Systole
Period of Ventricular Contraction
Phase 2,3,4
Isovolumetric Contraction
Rapid Ejection
Reduced Ejection
Ventricular Diastole
Period of Ventricular Relaxation
Phase: 5, 6, 7, 1
Isovolumetric relacation
rapid ventricular filling
reduced ventricular filling
Atrial systole
Atrial Systole
Initiation?
Propogation?
Initiated: Spread of action potential through atrium, causes P-wave of ECG
Causes transient rise (“a” wave) in Left Atrial Pressure (LAP)
Atrial Systole: Modulation
Rest/Exercise
Sympathetic Stimulation
At rest, atrial systole accounts for small fractionof ventricular filling
At exercise, atrial systole accounts for greater fraction of ventricular filling (less time available for passive filling due to increased HR)
Sympathetic Stimulation increases contribution of atrial systole to ventricular filling y increasing force of atrial contraction
Atrial Systole (Phase 1)
Blood Volume / EDV
Blood volume within ventricles greatest–End Diastolic Volume (EDV)
Isovolumic Contraction (Phase 2)
ECG
Ventricular Contraction and Valves
ECG: Spreat of AP through Ventricles generates QRS Complex of ECG and initiates ventricular contraction
Ventricular Contraction causes rapid increas in intraventricular pressure; once this exceeds atrial pressure, AV Valves Close (FIRST HEART SOUND S1)
What prevents AV valves from being forced into the atria during ventricular contraction?
They ar acnhored to the papillary muscles by chordae tendineae