4/29/24 - Lecture 16: Population Genetics I: Darwin Meets Mendel Flashcards
Evolution
Change in the heritable properties of populations over the course of generations
Genotype frequency
The proportion of individuals with a genotype in the population
Allele frequency
The proportion of an allele across all individuals or potential gametes in the population
Predicted genotypes in Hardy-Weinberg equilibrium using frequency of alleles
p^2 + 2pq + q^2 = 1
p: proportion of allele p
q: proportion of allele q
Assumptions of Hardy-Weinberg
No mutations
Large (infinite) population
Random mating
No gene flow from other populations
No natural selection
What if Hardy-Weinberg conditions are not occurring?
Some evolutionary process is happening, and the predicted genotype frequencies of the resulting population are DIFFERENT from the parent population
What if Hardy-Weinberg conditions are occurring?
The predicted genotype frequencies of the resulting population are the SAME as the parent population