3.8 Amides Flashcards
1
Q
What are amides?
A
Amides are the condensation of carboxylic acids and amines
2
Q
How are poly-amides formed?
A
Condensation of amino acids
OR
Condensation of di-oic acids and diamines
3
Q
What process returns an amide to its parent acid and amine?
A
Hydrolysis - through the addition of water or NaOH in a slow reaction
4
Q
What conditions will cause amide hydrolysis to occur more quickly?
A
Acid or basic condition will increase the speed of reaction
5
Q
Describe hydrolysis of amides in acidic conditions
A
The carboxylic acid will remain protonated
The base will accept a proton (on the nitrogen) and become a salt
6
Q
Describe hydrolysis of amides in basic conditions
A
The carboxylic acid will become de-protonated to form the carboxylate salt.
The amine will remain unreacted
