3.6 Amines

Question 1

Name of functional group of amine

Answer 1

amino

Question 2

What suffix is used to denote an amine?

Answer 2

• amine

e. g. ethanomine

Question 3

What type of bond is present in an amine?

Answer 3

A nitrogen-carbon bond

Question 4

What characteristic differentiate 1˚, 2˚ and 3˚ amines?

Answer 4

1˚ - one carbon-nitrogen bond
2˚ - 2 carbon-nitrogen bonds
3˚ - 3 carbon nitrogen bonds

Question 5

Why can amine act as proton acceptors/bases?

Answer 5

They have lone pair of electrons on the nitrogen that can become protonated

Question 6

How can an amine be converted to a more soluble salt?

Answer 6

The amine N can be protonated so it is now able to from ion-dipole interactions with water. previous amine were able to form only H-bonds with water.

Question 7

Why would an amine be converted to more soluble salt?

Answer 7

drugs containing amine groups are protonated so they are more soluble in blood and thus more easily distributed around the body