3.4.2 Neisseria & Other GNCs

Question 1

What is the flow chart for gram negative organisms?

Answer 1

Question 2

What is true about N. gonorrhoeae and its presence in humans?

Answer 2

Strict human pathogen

Question 3

Which pts infected with N. Gon will be symptomatic?

Answer 3

Men

Question 4

What are some of the clinical manifestations of disseminated N. Gon?

Answer 4

Infection of skin

Infection of joints

Neonatae: opthalmia neonatorum

Question 5

What are the two ways N. gon has variation in pili? (This prevent the production of an effective vaccine)

Answer 5

Antigenic variation: variable carboxy termini

Phase variation: pilin expression (on/off)

Question 6

How does N. gon acquire iron from its host?

Answer 6

Transferrin, lactoferrin, and hemoglobin-binding proteins

Question 7

Draw a diagram of the pathogenesis of N. gon

Answer 7

Question 8

Gram stain is very sensitive and specific in which subset of the population? What other tests must be run in other subsets of the population?

Answer 8

Symptomatic males

Culture must done for all other groups to rule out N. gon

Question 9

When do you start rx in pt with N. meningidis?

Answer 9

Start rx based on clinical suspicion

Question 10

What are the two vaccines given for N. meningidis?

Answer 10

Hib-MenCY (C, Y, Hib+, tetanus toxoid) - 6 wks to 18 mo

MenACWY (A,C,W,Y) - 2-55 yr olds

Question 11

What is most common serogroup of N. menin causing meningitis in the US population?

Answer 11

Serogroup B

Question 12

Tell me about E. corrodens?

Answer 12

Question 13

Digame sobre Aggregatibacter

Answer 13

Question 14

Tell me about K. kingae

Answer 14

Question 15

Tell me about capnocytophaga

Answer 15

Question 16

Que es Pasteurella

Answer 16