3.4.1 DNA, genes and chromosomes Flashcards
DNA storage
Eukaryotic DNA: long, linear, associated with proteins (histones), tightly coiled into chromosomes (
Prokaryotic DNA: short, circular, not associated with proteins
Mitochondria and chloroplasts DNA
Similar to prokaryotic DNA - short, circular, not associated with proteins
Genes
Sequence of DNA bases that code for:
The amino acid sequence of a polypeptide (primary sequence)
A functional RNA e.g. ribosomal RNA and tRNAs
Occupies a fixed position (locus) on a particular DNA molecule
Nature of the genetic code
Sequence of DNA triplets (mRNA codons) codes for sequence of amino acids
Universal: the same specific DNA base triplets code for the same amino acids in all living organisms
Non-overlapping: discrete, each base can only be used once and in only one triplet
Degenerate: the same amino acid can be coded for by more than one base triplet
DNA triplet (mRNA codon)
sequence of 3 bases which code for a specific amino acid
Eukaryotes DNA
Non-coding multiple repeats between genes
Within genes - only exons code for amino acid sequences, which are separated by one or more non-coding sequences (introns)
Genome
Complete set of genes in a cell, including those in mitochondria and/or chloroplasts
Proteome
The full range of proteins that a cell/genome is able to produce
Allele
Different versions (sequence of bases/triplets) of the same gene
Homologous pair of chromosomes
Same size chromosomes with same genes, but different alleles