32_Cancer Biology

Question 1

What are the most common forms of cancers? Where do they originate from?

Answer 1

carcinomas (90%), epithelial cells

Question 2

Which cancers originate from connective tissue?

Answer 2

sarcomas (1-2%)

Question 3

Which cancers arise from blood-forming cells?

Answer 3

leukemias

Question 4

Which cells do lymphomas originate from?

Answer 4

cells of the immune system

Question 5

What are the three most common types of cancer?

Answer 5

Lung & bronchus
Prostate
Breast

Question 6

How is density-dependent inhibition detected?

Answer 6

Through secreted proteins

Question 7

What key feature is present in density-dependent inhibition, but ceases in contact inhibition?

Answer 7

cell motility

Question 8

What are clumps of cancer cells growing atop each other called?

Answer 8

foci

Question 9

Are serum-deprived cancer cells able to grow?

Answer 9

YES because they are growth-factor independent.

Question 10

How can viruses transform cells to become cancerous?

Answer 10

Viruses carry genes whose protein products may interfere with the cell’s growth-regulating activities.

Question 11

Which cancerous cell type do most drugs target? (in terms of SC type)

Answer 11

pluripotent progenitor cells (b/c of their rapid cell cycling, most likely origin)