3.1.2: Transport in animals Flashcards
Why do multicellular organisms require a transport system?
- Most have high metabolic demands
- Substance absorbed in one part of the organism need to be transported to another –> distance is too great for diffusion/diffusion alone would be too slow
Types of transport system
• Open
• Closed
⟶ Single closed
⟶ Double closed
Open circulatory system found in:
Invertebrates
Features of an open circulatory system
- Few vessels
- Haemolymph pumped straight from heart into body cavity (haemocoel)
- Haemolymph comes into direct contact with tissues and cells
- Very low pressure
What is haemolymph?
The transport medium found in the open circulatory systems of invertebrates. Carries food, nitrogenous waste products and cells to defend against disease. DOES NOT CARRY GAS EXCHANGE PRODUCTS.
What are the limitations of an open circulatory system?
✘ Steep diffusion gradients cannot be maintained.
Closed circulatory system found in:
• Cephalopod molluscs, annelid worms, echinoderms, vertebrates.
Features of a closed circulatory system:
- Transport medium (blood) enclosed within vessels –> does not directly contact body cells
- Blood pigment (haemoglobin) carries respiratory gases
- Substances enter and leave blood by diffusion through walls of the blood vessels
Benefits of a closed circulatory system:
✔︎ High pressure enables steep concentration gradient to be maintained
Single closed circulatory system found in:
- Fish
* Annelid worms
Double circulatory system found in:
- Birds
* Mammals
Benefits of a double circulatory system:
✔︎ Each circuit only passes through 1 set of capillaries
∴ High pressure and steep concentration gradient can be maintained
Limitations of a single circulatory system:
✘ Lower pressure than double circulatory system
∴ Cannot maintain as steep a concentration gradient
How are the limitations of a single circulatory system overcome in fish?
- Lower metabolic demands
* Gills very good at removing oxygen from water so blood carries comparatively more oxygen
Single circulatory system (closed)
- Blood pumped straight from heart, to gas exchange surface, to body cells
- Blood travels through 2 sets of capillaries before returning to heart
Double circulatory system (description)
- Blood pumped from heart, to gas exchange surface, to heart, then to body cells
- Blood travels through 1 set of capillaries before returning to the heart
Bicuspid valve
- Left atrioventricular valve
* Consists of two flaps
Tricuspid valve
- Right atrioventricular valve
* Consists of three flaps
Atrial systole
- Walls of atria contract
- Push remaining blood from atria into ventricles
- Through atrioventricular valves
- Semilunar valves are closed
- Ventricles fill with blood
Ventricular systole
- Walls of ventricles contract
- Blood pressure inside ventricles increases
- Atrioventricular valves are forced shut
- Blood is pumped out into the aorta and pulmonary artery
- Through the semilunar valves
- Atria start to refill as they collect blood from the veins
Diastole
• Heart relaxes
• Pressure inside heart decreases
• Semilunar valves close
⟶ preventing backflow of blood into ventricles from the aorta and pulmonary artery
• When pressure of blood in ventricles falls below pressure of blood in atria, atrioventricular valves open
• Blood from atria flows into ventricles
Myogenic
Contraction is initiated from within the muscle itself rather than from external nerve impulses.
Why would a hole in the septum be a problem?
- Mixing of deoxygenated and oxygenated blood would occur.
- Deoxygenated blood may never reach lungs
- Lack of oxygenated blood to body cells (which need it in order to carry out aerobic respiration)
Why does the left ventricle have such a thick wall?
- To pump blood at v. high pressure into the aorta
* Needs to exert high pressure –> needs to circulate to body cells a great distance away from the heart
How does cardiac muscle differ to other muscles in the body?
- Myogenic
* Does not get fatigued and require rest
Why must contractions of 4 chambers of the heart be synchronised?
To avoid fibrillation.
What is the SAN?
Sino-atrial node: patch of tissue which generates electrical activity.
• Initiates wave of electrical excitation at regular intervals
• Causes atria to contract
Controlling the heart beat
1) Excitation spreads over the walls of both atria causing contraction (atrial systole)
2) Disc of tissue at the base of the atria is insulating; contraction cannot pass to ventricles
3) Atrioventricular node is the only route for the excitation ⟶ slight delay before ventricles contract allows all the blood from the atria to empty into the ventricles
4) AVN stimulates the bundle of His
5) Purkyne fibres spread through the spread out through the ventricle walls causing contraction starting at the apex (spreads base up)
Bundle of His
Conducting tissue made up of Purkyne fibres
AVN
Atrio-ventricular node: path by which electrical excitation passes from the atria to the ventricles
Why is it beneficial that the electrical activity initiated from the SAN passes across the tops of the atria and then down across the atria?
- Ensures both atria contract together
* Ensures the atria contract top to bottom (this pushes blood towards and into the ventricles)
Advantage of the short delay in transmission of electrical activity through the AVN?
• Ensures atria ave time to empty blood into ventricles BEFORE the ventricles contract
Advantage of impulse passing down the bundle of His then spreading up from the apex?
- Means that ventricular contraction occurs apex to top of heart
- Blood is pushed up to the semilunar valves –> leading to aorta/pulmonary artery
Why is it beneficial for heart rate to increase during exercise?
- Higher heart rate = higher cardiac output = quicker circulation of blood delivering oxygen to cells
- Increased rate of O₂ delivery –> increases rate of aerobic respiration to release ATP for muscle contraction
- Reduces anaerobic respiration
- Removal of waste products of anaerobic respiration
Electrocardiagrams
- Measure the electrical activity of the heart
* Used to diagnose heart problems
Cardiac output
the volume of blood pumped by one ventricle of the heart in 1 minute.
Formula for cardiac output
Cardiac output = heart rate x stroke volume
Heart rate
Number of cardiac cycles per minute
Stroke volume
Volume of blood pumped out of the ventricle during one cardiac cycle (one beat)
Endurance athletes (heart)
Higher stroke volume –> lower heart rate at rest
Blood composition
~55% plasma
~1% WBCs
~45% erythrocytes
Erythrocytes contents
- Full of haemoglobin (millions of molecules per cell)
- 4 polypeptide chains (2 alpha globin, 2 beta globin)
- Haem groups (1 prosthetic group per chain)
- Each group can bind reversibly to 1 O₂
- Each haemoglobin can carry 4O₂ molecules
Erythrocyte flattened biconcave shape
- Increases SA:V ratio, enables more efficient diffusion
* All haemoglobin close to surface –> short diffision pathway
Erythrocyte structure
- Flattened biconcave disc
- Small (~7µm diameter)
- Contains haemoglobin
- No organelles
- Thin centre
Erythrocyte small (~7µm diameter)
- Can pass through capillary
* Touches the side of the capillary: reduce distance for oxygen fo diffuse
Erythrocyte lack of organelles
• Maximise space for haemoglobin
Erythrocyte thin centre
- Flexible (can squeeze through narrow capillary)
* Short diffusion pathway centre of cell
Formula for the partial pressure of oxygen
Air pressure x 0.21 = pO₂
At a high pCO₂ …
- Haemoglobin has a lower affinity for oxygen
* Releases oxygen from oxyhaemoglobin
3 ways in which CO₂ is transported
- Dissolved in plasma (5%)
- Binds to amino groups of polypeptide chains of haemoglobin (10-20%)
- Converted to hydrogen carbonate ions in RBCs (75-85%)
Large vein diameter
Larger than 1cm
Medium vein diameter
Less than 1cm
Venule diameter
0.1mm
Composition of large vein
Elastin
Smooth muscle
Collagen
Composition of medium vein
Elastin
Smooth muscle
Collagen
(all less than large vein)
Composition of venule
Collagen
Aorta diameter
2.5 cm
Medium sized artery diameter
0.4 cm
Arteriole diameter
30 um
Aorta composition
Elastin fibres (many) Smooth muscle (little) Collagen (moderate-high)
Medium artery composition
Elastin fibres (many) Smooth muscle (lots; more than aorta) Collagen (very little)
Arteriole composition
Elastin fibres (few) Smooth muscle (moderate - highest of alll 3) Collagen (moderate)
Why do arteries need smooth muscle?
Contract for vasoconstriction
Why do arteries need elastin?
Faciliates relaxation of smooth muscle, evens out pressure changes (more in lungs)
How is the heart action coordinated?
Vagus nerve (parasympathetic nervous system) connects from the cardiovascular centre in medulla oblongata to SAN Action potentials from the vagus nerve slow the heart rate
Why might actions potentials be sent via vagus nerve?
To slow heart rate
e.g. if baroreceptors detect high blood pressure
or
chemoreceptors detect low CO₂, high pH