3.08 Blood Typing and Hemoglobin Formation Flashcards
T/F Acid hematin method has low sensitivity and high specificity
F. High sensitivity and low specificity.
Why is HCL used to test for Hemglobin estimation?
HCl causes lysis of RBC and binds with rBC forming acid hematin
More commonly used hemoglobin estimation methods and is the most reliable of all the methods
Cyan hemoglobin method
Measures the concentration of hemoglobin
Direct spectrometry
Measures light scattered by particles in a suspension.
Nephelometry
Uses size and granularity to identify which types of cells are present
Flow cytometry
Which of the following will you expect a decreased Hgb?
High altitude, CHF, parasitic infections, smoking?
Parasitic infections
Which of the following will show a increased Hgb?
Iron or copper deficiency, kidney disease, Obstructive lung disease, drugs or lead poisoning.
Obstructive lung disease.
Agglutination in anti sera color blue indicates what blood type?
Blood type A
What do ABO genes encode for?
Transferases
T/F AB gene is recessive.
False. It is co-dominant
Treatment for Rh neg mother with Rh pos father
RhoGAM
Making of immature RBCs of fetus to compensate for destruction of RBCs.
Erythroblastosis Fetalis
Once bilirubin crosses the blood brain barrier, it is called_____
Kenicterus
