3 Substance exchange- Gas exchange (humans) Flashcards

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1
Q

Where does human gas exchange take place?

A

Lungs- specialised organs for the quick exchange of O2 & CO2 with the bloodstream

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2
Q

What structures do the lungs consist of?

A

Trachea, bronchi, bronchioles and alveoli

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3
Q

What is the structure and function of the trachea?

A

-Entrance to human gas exchange system
-Breathe in; air flows through trachea
-Ridges of cartilage surround the front to provide protection and structure; none at the back so that oesophagus isn’t constricted

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4
Q

What is the structure and function of the bronchi?

A

-Divide into 2 from trachea
-Air flows along each bronchus to a lung
-Made from cartilage and smooth muscle

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5
Q

What is the structure and function of the bronchioles?

A

-Many smaller bronchioles divide from each bronchus
-Branch throughout lungs into small air-sacs, alveoli

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6
Q

What is the structure and function of the alveoli?

A

-Sacs, fill with air when you breathe in
-Oxygen in alveoli diffuses into bloodstream and CO2 from bloodstream diffuses into alveoli
-Millions in the lungs
-Provide large surface area for gas exchange

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7
Q

How is ventilation controlled?

A

-Controlled by ribcage, intercostal muscles and diaphragm
-When you breathe in, these move so that lungs fill with air
-When you breathe out, these move so air can leave the lungs

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8
Q

What is the structure and function of the capillaries?

A

-Capillary network surrounds each alveolus
-Provide large surface area for gas exchange between alveoli and bloodstream

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9
Q

What is the structure and function of the alveolar epithelium?

A

-Single layer of epithelial cells, line walls of alveoli.
-Provide very short diffusion distance from alveoli to capillaries: maximises rate of gas exchange

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10
Q

How is a steep concentration gradient maintained?

A

-Capillaries supply CO2 to alveoli and O2 is rapidly carried away from alveoli
-Quick transport of gases in bloodstream maintains steep concentration gradient of O2 and CO2
-Allows quick diffusion of gases into and out of bloodstream

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11
Q

What are the steps involved in breathing in/ inspiration?

A

Air flows into lungs, O2 diffuses into bloodstream

  1. The external intercostal muscles (surrounding ribcage) contract
    Diaphragm contracts, moves downwards
    Energy is required to power this
    2.External intercostal muscles move ribcage upwards and outwards. Diaphragm moves downwards. Volume of thoracic cavity increases
  2. Pressure in lungs decreases due to increasing volume in thoracic cavity. Pressure gradient created- outside and inside of the lungs
  3. Air flows inside the lungs down the pressure gradient, and down the trachea into the alveoli
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12
Q

What are the steps involved in breathing out/expiration ?

A

Air flows out of lungs, CO2 diffuses out of bloodstream

1.External intercostal muscles relax, internal intercostal muscles contract and diaphragm relaxes, moves upwards
2.Internal intercostal muscles move rib cage downwards + inwards, diaphragm moves upwards. Volume of thoracic cavity decreases
3. Pressure in the lungs increases due to decreasing pressure in thoracic cavity, creating a pressure gradient between the outside and inside of the lungs
4.Air flows out of the lungs down the pressure gradient, and out of the alveoli up the trachea

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13
Q

What does lung disease affect and how?

A

The ability of the lungs to exchange gases over their surface. Can be direct tissue damage or reduced ability to ventilate

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14
Q

What are some examples of lung diseases?

A

Asthma
Pulmonary fibrosis
Tuberculosis
Emphysema

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15
Q

What are the causes of gas exchange problems?

A

The exchange system is damaged, causes of problems can include;
-Decreased surface area
-Increased diffusion distance
-Decreased concentration gradient

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16
Q

What are some symptoms of gas exchange/ventilation issues?

A

-Coughing mucus/ blood
-Faster, shallower breathing
-Blood oxygen saturation readings below 90%
-Fatigue

17
Q

What is emphysema and its effects?

A

-Caused by smoking/ air pollution
-Dirt & bacteria trapped in alveoli, damage their walls
-Decreases surface area of walls and therefore rate of gas exchange, as alveoli provide a large surface area for gas exchange

18
Q

What is asthma and its effects?

A

-Increases production of mucus by epithelial cells, which increases the length of diffusion distance, decreasing rate of gas exchange
-Asthma attack causes smooth muscle in bronchioles to contract; making it difficult to breathe

19
Q

What is tuberculosis and its effects?

A

-TB bacteria can infect lungs, damaging lung tissue
-Cells of immune system can damage lungs also; decreasing tidal volume (volume of air in a normal breath)

20
Q

Why does smoking affect the lungs?

A

Harmful impacts on lung function. Smoke has harmful chemicals, like nicotine, carbon monoxide and carcinogens (cancer-causing chemicals)

21
Q

How does smoking cause bronchitis?

A

Smoke breathed in= damages cilia cells of airway
Cilia can’t waft away mucus produced by goblet cells, so it builds up
Can lead to bronchitis, airways partly blocked with mucus

22
Q

How does smoking cause heart disease and strokes?

A

-Nicotine is very addictive, puts strain on heart
-Carbon monoxide reduces ability of red blood cells to carry oxygen, can put strain on heart
-Can both cause heart disease and strokes