3: Interstitial Lung Disease Flashcards
What is interstitial lung disease
Inflammation interstitial and alveoli
What is the most common cause of interstitial lung disease
Idiopathic pulmonary fibrosis (IPF)
What are 3 occupation causes of interstitial lung disease
- Berryliosis (Radiation pneumoconiosis)
- Asbestosis
- Silicosis
What are 4 medications that cause pulmonary fibrosis
- Amiodarone
- Phenytoin
- Nitrofurantoin
- Bleomycin
What systemic disorders may cause pulmonary fibrosis
RA
Sjogrens
SLE
Sarcoidosis
What is a risk factor for idiopathic pulmonary fibrosis
Smoking
What are symptoms of interstitial lung disease
- Exertional dyspnoea, progress to dyspneoa at rest
- Persistent non-productive cough
- Fatigue
What is a sign interstitial lung disease
Clubbing
What is auscultated in interstitial lung disease
Bi-basal fine end-inspiratory crackles (Rales)
What is the problem with idiopathic pulmonary fibrosis
70% will not respond to treatment and will progress to respiratory failure
what will be seen on spirometry in interstitial lung disease
restrictive defect:
FEV1/FVC > 0.7
what will be seen on CXR in interstitial lung disease
- Fibrosis
- Honeycombing (Late-sign)
what test may be performed in interstitial lung disease
diffusion capacity lungs for carbon monoxide
how is idiopathic pulmonary fibrosis managed
- Oxygen
- Pulmonary rehabilitation