1(E) Respiratory Failure Flashcards
When does respiratory failure occur
When gas exchange is inadequate resulting in hypoxia
What defines respiratory failure
PaO2 less-than 8kPa
What is type I respiratory failure
PaO2 less than 8kPa
Normal PCO2
What causes type I respiratory failure mainly
V-Q mismatch
What are 6 causes of V-Q mismatch
- PE
- Pneumonia
- Pulmonary oedema
- Asthma
- Emphysema
- Pulmonary Fibrosis
- ARDS
What else can cause type I resp failure
Alveolar Hyperventilation
Right-to-Left cardiac shunt
Define type II respiratory failure
Hypoxia (PaO2 < 8) with hypercapnia (PaCO2 >6)
What is the main mechanism if type 2 respiratory failure
Alveolar hypoventilation without V-Q mismatch
What are the 4 etiological categories of type 2 respiratory failure
- NM Disease
- Pulmonary Disease
- Chest wall disease
- Reduced resp drive
What are the 4 pulmonary diseases causing type 2 respiratory failure
- COPD
- Asthma
- End-stage pulmonary fibrosis
- OSA
What are 3 causes of reduced resp drive
CNS Tumour
Medication (Opioids)
Trauma
What NM disease may cause type 2 resp failure
Myasthenia Gravis MND Poliomyelitis Gullian Barre Cervical Cord Lesion
What does poliomyelitis affect
Anterior horn cells - causing a LMN lesion
What chest wall deformities can cause T2RF
Flail chest
Kyphoscoliosis
What is a mnemonic to remember symptoms of hypoxia
DRAC
What are symptoms of hypoxia
Dyspnoea
Restless
Agitated
Confused
What is a sign of hypoxia
Cyanosis
What are 3 consequences of long-term hypoxia
Polycythaemia
Pulmonary HTN
Cor Pulmonale
What is the main symptom of hypercapnia
Headache
What are 5 symptoms of hypercapnia
Headache Confusion Drowsiness Coma Peripheral Vasodilation
What are 4 signs of hypercapnia
Bounding pulse
Tachycardia
CO2 Flap
Papilloedema