1(E): PE Flashcards

1
Q

Define a PE

A

Occlusion pulmonary arteries by solid, gas or liquid matter

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2
Q

What is the most common cause of PE

A

Thrombus from DVT

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3
Q

Explain incidence of PE with age

A

Increases with age

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4
Q

What factors increase incidence of PE

A
  • Malignancy
  • Active Inflammation: IBD
  • Surgery - particularly to lower limbs
  • Immobility
  • pregnancy
  • COCP
  • HRT
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5
Q

what is the typical triad of symptoms in PE

A
  • Haemoptysis
  • Dyspnoea
  • Pleuritic chest pain
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6
Q

what is a saddle embolus

A

Large embolus that occludes bifurcation of pulmonary arteries

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7
Q

how may a saddle embolus present

A

Shock

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8
Q

what is the most common sign of PE

A

Tachypnoea (90%)

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9
Q

what may be seen on observations in PE

A
  • Tachypneoa
  • Tachycardia
  • Fever
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10
Q

what may be ausculated in PE

A

Crackles
Loud S2
Pleural Rub

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11
Q

what may be seen on palpation in PE

A

Raised JVP

Right ventricular heave

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12
Q

why does a pleural rube occur

A

Inflammation pleura cause loss fluid between and friction as they rub together

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13
Q

when should PE always be considered as a differential

A

Sudden-collapse in person two weeks after surgery

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14
Q

where do majority of PE’s arise

A

DVT above the knee

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15
Q

what should be done first in PE

A

decide whether individual is at high or low-risk of death

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16
Q

how is it deiced whether individual with a PE has a high or low risk of death

A

High risk of death includes:

  • Systolic BP less than 90
  • Decrease in systolic BP of 40 in 15m
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17
Q

if a low-risk of death, how is the person assessed

A

Modified wells score

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18
Q

what is mnemonic to remember components of the modified wells score

A

SHRIMPA

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19
Q

what are the components of the modified wells score

A

Signs and symptoms of DVT

Haemoptysis

Rate of heart >100

Immobility

Malignancy (Palliative, Treatment in past 6 months)

PMH DVT or PE

Alternative diagnosis less likely

20
Q

in the modified wells score - what defines high risk of PE

A

More than 4

21
Q

how are individuals with high probability of PE investigated

22
Q

what should be checked before CTPA

23
Q

what is a contraindication to CTPA

A

Contrast Allergy

Poor Renal Function

24
Q

if GFR less than 35 or contrast allergy, what is used

25
what defines low risk of PE
less than 4
26
if individual is low risk of PE what is performed
D-Dimer
27
if D-dimer is positive, what test is performed to confirm PE
CTPA
28
aside from d-dimer, CTPA, what investigation may be ordered for PE
ECG
29
what is the most common sign of PE on ECG
Sinus tachycardia
30
what other sign of PE can be seen on ECG
- S1T3Q3 | - Right bundle branch block with right-axis deviation
31
if suspected delay in CTPA, what should be given
LMWH or fondaparinux
32
in PE, what is first line management
Oxygen
33
what drugs are given to all individuals with PE
Morphine | IV LMWH/ Fondaparinux
34
if someone has a creatinine clearance of less-than 15 what is given as an alternative to LMWH
Unfractioned heparin
35
if individual with massive PE, how are they managed
- Resuscitation if in shock | - Thrombolysis with alteplase
36
what is first line if a non massive PE
Rivaroxaban
37
If PE is confirmed, how long should rivaroxaban be continued for
3W. | Also calculate pulmonary embolism severity index
38
What is an alternative to rivaroxaban
Warfarin
39
If a provoked PE, how long is warfarin continued for
3-months
40
If an unprovoked PE or active cancer, how long is warfarin continued for
6-months
41
how long should LMWH be carried on for
5-days or until 24h after INR is greater than 2.0 = whichever is longer
42
summarise management of PE
1. Oxygen 2. LMWH 3. Morphine 4. If haemodynamically unstable resuscitate and thrombolyse. If not, give rivaroxaban or warfarin
43
how are recurrent PE's managed
Inferior vena cava filter
44
what is used to determine severity of PE
Pulmonary Embolism Severity Index (PESI)
45
what happens to PESI class I and 2 individuals
Early discharge
46
What happens to PESI class 3,4 and 5 individuals
Further test with troponin T, ECG and eCHO
47
what are 5 risks of PE
- Recurrence - RVF - Sudden cardiac death due to PEA - Atelectasis - Pulmonary infarction caused by embolism if segmental arteries = causing wedge shaped haemorrhage pulmonary infarction