2: Pleural Effusion Flashcards

1
Q

What is a pleural effusion

A

Fluid in pleural space

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2
Q

How are effusions divided

A

Into either exudates or transudates depending on protein content

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3
Q

What is an exudate

A

Protein >30g/L

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4
Q

What are the 4 etiological categories of exudate

A
  • Infectious
  • Malignant
  • Autoimmune
  • Other
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5
Q

What 3 infections can cause exudate

A

Pneumonia
TB
Empyema

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6
Q

What malignancies can cause exudate

A

Primary lung
Mets
Lymphoma
Mesothelioma

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7
Q

What are 4 autoimmune causes of exudate

A

RA
Sarcioidosis
SLE
Vasculitis

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8
Q

What are 4 other causes of exudate

A

PE
Haemothorax
Chylothorax
Pancreatitis

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9
Q

What is a transudate

A

Protein content less than 30g/L

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10
Q

What are the 3 etiological categories of transudates

A
  • Increase venous pressure
  • Protein deficiency
  • Other
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11
Q

What are 3 causes of increase venous pressure

A

HF
Constrictive pericarditis
Fluid Overload

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12
Q

What are 3 causes of protein deficiency

A

Cirrhosis
Protein-losing enteropathy
Nephrotic syndrome

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13
Q

What are 2 other causes of transudate

A

Hypothyroidism

Meig’s syndrome

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14
Q

What is Meig’s syndrome

A

Ovarian fibroma and right pleural effusion

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15
Q

What defines a small pleural effusion

A

Less than 200ml

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16
Q

How do small pleural effusions present

A

Asymptomatic

17
Q

How do large pleural effusions present

A
  • Dyspneoa
  • Pleuritic chest pain
  • Dry non-productive cough
18
Q

Why do large pleural effusions cause dyspneoa

A

Compress lung

19
Q

In large effusions, explain position trachea

A

Will be deviated away from the lesion

20
Q

What is first-line investigation for pleural effusion

21
Q

When can pleural effusion only be seen on CXR

22
Q

How does pleural effusion present on CXR

A
  • Blunting costophrenic or cardiophrenic angle
  • Fluid in horizontal or oblique fissures
  • Visible meniscus
  • Mediastinal shift away from side affected - if large
23
Q

What is second-line for pleural effusion

A

US-Guided needle aspiration

24
Q

What criteria may be used to evaluate pleural effusion

A

Light’s Criteria

25
When is lights criteria used
If protein in fluid is borderline 25-35g/L
26
What does lights criteria state
That if any of the following are present, the fluid is more likely a exudate than transudate: 1. Pleural protein/Serum protein >0.5 2. Pleural LDH/Serum LDH >0.5 3. Pleural LDH in upper 2/3rd of normal LDH
27
What does low glucose in pleural fluid imply
- TB | - RA
28
What does raised amylase in pleural fluid indicate
- Pancreatitis | - Oesophageal perforation
29
What does blood stained pleural effusion indicate
- TB - PE - Mesothelioma
30
What is third-line investigation for pleural effusion
Contrast CT
31
How are pleural effusions managed
Treat cause | May use chest drain
32
What are 3 indications for placing a chest tube in pleural effusion
1. Cloudy fluid 2. pH less than 7.2 3. Symptomatic
33
At what rate should fluid be removed from chest tube in pleural effusion
1.5L per 24h
34
What are methods to manage recurrent pleural effusions
- Recurrent aspiration - Pleurodesis - Indwelling catheter - Opioids to relieve breathlessness