3/24/16 Flashcards

1
Q

Aldesleukin (IL-2)

A

Renal cell carcinoma

Metastatic melanoma

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2
Q

Infected T-cell cell demonstrates multilobulated nucleus described as cloverleaf of flower cells

A

HTLV-1Adult T-cell Leukemia

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3
Q

Contralateral face and arm weakness of the upper motor neuron type, with gaze preference towards the side of the lesion and variable unilateral neglect

A

MCA (middle cerebral infarct)

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4
Q

Excessive, intense, or prolonged grief, as well as grief that is delayed, inhibited or denied

A

Pathologic grief

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5
Q

Small, gram-positive with tumbling motility

A

Listeria Monocytogenes

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6
Q

Albuminocytologic dissociation

A

Elevated CSF levels of protein with normal cell count

Seen in Guillian-Barre

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7
Q

Drug used to treat Chagas disease caused by Trypanosoma Cruzi

A

Nifurtimox

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8
Q

Factor XI (hemophilia C) AR common in

A

Ashkenazi Jews

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9
Q

Fat, elongated uvula, daytime sleepiness, inability to concentrate, and hypertension

A

OSA (obstructive sleep apnea)

Recurrent asphyxiarespiratory acidosis (if chronic)compensated by retention of renal HCO3 (metabolic alkalosis)

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10
Q

Chemical antagonist-binds directly to an agonistprevents agonist binding to target
Binds toxic metal such as copper (Wilson disease)

A

D-Penicillamine

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11
Q

Coltivirus

A

Double-stranded RNA virus in Reovirus family

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12
Q

Primary somatosensory cortex (ex: for right side)

A

Left postcentral gyrus

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13
Q

First 15 degrees of abduction of the arm

A

Supraspinatus
Most common rotator cuff injury
Pain anteriorly and superiorly to glenohumeral joint during abduction

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14
Q

Seborrheic keratosis

A

Benign, flat, pigmented squamous proliferation with keratin cysts

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15
Q

Dermatitis herpetiformis is associated with

A

Celiac disease (pruritic papules and vesicles)

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16
Q

VTNRs (variable numbers of tandem repeats) like CAG in Huntington’s are detected by:

A

DNA-DNA hybridization

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17
Q

HIV cancer associations

A

Kaposi and non-Hodgkin

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18
Q

Dipalmitoylphosphatidycholine

A

Surfactant

Give mother glucocorticoids to prevent

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19
Q

Serine protease inhibitor alpha-1 antitrypsin usually functions to inhibit

A

neutrophil elastase

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20
Q

Faggot cells

A

APL (M3 subtype of AML)

21
Q

Most common malignancy of children?

A

ALL

22
Q

At birth all oocytes are arrested in ___________________

A

Prophase of meiosis I

23
Q

Anti-Cardiolipin antibodies are detected in syphilis (non-specific marker)

A

Cardiolipin is a phospholipid found in the inner mitochondrial membrane

24
Q

The transplant killer

A

CMV-periventricular meningeal enhancement

25
Q

Tranylcypromine

A

Non-selective monoamine oxidase inhibitor (MOA)

26
Q

Follicular thyroid carcinoma

A
Hematogenous spread (breaks the rule)
Can go to bone
27
Q

A mold with septate hyphae that branch at a V-shaped 45-degree angle

A

Aspergillus fumigatus

28
Q

Cup-shaped cysts with intracystic bodies and thick cell wall

A

Pneumocystis jiroveci

29
Q

Heavily encapsulated non-dimorphic yeast that is found in soil and pigeon droppings

A

Cryptococcus neoformans

30
Q

Inheritance of G6PD

A

X-linked recessive

31
Q

The use of positive and negative consequences (reinforcement or punishment) to modify a certain behavior

A

Operant conditioning

32
Q

Low blood solubility (ex: Nitrous oxide) will rapidly induce anesthesia and patients will recover…

A

QUICKER

In contrast, high solubility (halothane) will have a longer time to induction and a slower time to recovery

33
Q

Minimum alveolar concentration

A

Potency of inhaled anesthetics
Concentration of gas that is needed to eliminate movement in 50% of patients
Small MAC= POWERFUL AF

34
Q

Pre-renal azotemia causes (reduced GFR)

A

Heart failure
Sepsis
Renal artery stenosis
=Elevated BUN:Cr ratio and FeNa is less than 2% (greater would be intrinsic)

35
Q

permeability barrier in the nervous system

A

Perineurium

36
Q

Systemic retinoic acid is

A
CATEGORY X (3-5 weeks and woman don’t even know she Prego) 
Missing ears or spontaneous abortions
37
Q

Use of Disulfiram is an example of what type of conditioning

A

Aversive conditioning (a part of classical conditioning)

38
Q

Fetal hydantoin syndrome is due to

A

Maternal use of antiepileptic drugs such as Phenytoin

39
Q

Antineoplastic agent that is an MAO inhibitor. Patients must avoid dat cheese/tyramine to prevent HTN crisis

A

Procarbazine

40
Q

Remember you count up the reflexes:

A

Achilles reflex: S1 S2
Knee Jerk: L3 L4
Biceps: C5 C6
Triceps: C7 C8

41
Q

Long-term exercise has been shown to increase cell surface

A

GLUT-4

42
Q

IgG anti-RhD antibody that binds to and destroys RhD-positive fetal cells in the maternal circulation

A

Rhogam

43
Q

Niacin deficiency (Vitamin B3) = 3D’s

A

Diarrhea
Dermatitis
Dementia

44
Q

ADPKD

A

Polycystin 1 gene = Chromosome 16
Polycystin 2 gene = Chromosome 4
Symptoms: abdominal pain, hematuria, polyuria and nocturia
Berry aneurysms and MVP

45
Q

DNA is transferred from one bacterium to another (direct cell to cell contact)

A

Conjugation

46
Q

Nonsmokers and woman lung cancer

A

Adenocarcinoma

47
Q

What ADR do busulfan, amiodarone, methotrexate, Nitrofurantoin, and radiation chest therapy

A

Pulmonary fibrosis

48
Q

What two viruses are NK cells most important in fighting

A

EBV
Herpesviruses
NK cells recognize their lesser amount of MHC I expression

49
Q

Horizontal nystagmus on lateral gaze at therapeutic levels. Vertical nystagmus, double vision, sedation, and cerebellar ataxia and tremor at supratherapeutic level

A

Phenytoin