3/24/16 Flashcards
Aldesleukin (IL-2)
Renal cell carcinoma
Metastatic melanoma
Infected T-cell cell demonstrates multilobulated nucleus described as cloverleaf of flower cells
HTLV-1Adult T-cell Leukemia
Contralateral face and arm weakness of the upper motor neuron type, with gaze preference towards the side of the lesion and variable unilateral neglect
MCA (middle cerebral infarct)
Excessive, intense, or prolonged grief, as well as grief that is delayed, inhibited or denied
Pathologic grief
Small, gram-positive with tumbling motility
Listeria Monocytogenes
Albuminocytologic dissociation
Elevated CSF levels of protein with normal cell count
Seen in Guillian-Barre
Drug used to treat Chagas disease caused by Trypanosoma Cruzi
Nifurtimox
Factor XI (hemophilia C) AR common in
Ashkenazi Jews
Fat, elongated uvula, daytime sleepiness, inability to concentrate, and hypertension
OSA (obstructive sleep apnea)
Recurrent asphyxiarespiratory acidosis (if chronic)compensated by retention of renal HCO3 (metabolic alkalosis)
Chemical antagonist-binds directly to an agonistprevents agonist binding to target
Binds toxic metal such as copper (Wilson disease)
D-Penicillamine
Coltivirus
Double-stranded RNA virus in Reovirus family
Primary somatosensory cortex (ex: for right side)
Left postcentral gyrus
First 15 degrees of abduction of the arm
Supraspinatus
Most common rotator cuff injury
Pain anteriorly and superiorly to glenohumeral joint during abduction
Seborrheic keratosis
Benign, flat, pigmented squamous proliferation with keratin cysts
Dermatitis herpetiformis is associated with
Celiac disease (pruritic papules and vesicles)
VTNRs (variable numbers of tandem repeats) like CAG in Huntington’s are detected by:
DNA-DNA hybridization
HIV cancer associations
Kaposi and non-Hodgkin
Dipalmitoylphosphatidycholine
Surfactant
Give mother glucocorticoids to prevent
Serine protease inhibitor alpha-1 antitrypsin usually functions to inhibit
neutrophil elastase
Faggot cells
APL (M3 subtype of AML)
Most common malignancy of children?
ALL
At birth all oocytes are arrested in ___________________
Prophase of meiosis I
Anti-Cardiolipin antibodies are detected in syphilis (non-specific marker)
Cardiolipin is a phospholipid found in the inner mitochondrial membrane
The transplant killer
CMV-periventricular meningeal enhancement
Tranylcypromine
Non-selective monoamine oxidase inhibitor (MOA)
Follicular thyroid carcinoma
Hematogenous spread (breaks the rule) Can go to bone
A mold with septate hyphae that branch at a V-shaped 45-degree angle
Aspergillus fumigatus
Cup-shaped cysts with intracystic bodies and thick cell wall
Pneumocystis jiroveci
Heavily encapsulated non-dimorphic yeast that is found in soil and pigeon droppings
Cryptococcus neoformans
Inheritance of G6PD
X-linked recessive
The use of positive and negative consequences (reinforcement or punishment) to modify a certain behavior
Operant conditioning
Low blood solubility (ex: Nitrous oxide) will rapidly induce anesthesia and patients will recover…
QUICKER
In contrast, high solubility (halothane) will have a longer time to induction and a slower time to recovery
Minimum alveolar concentration
Potency of inhaled anesthetics
Concentration of gas that is needed to eliminate movement in 50% of patients
Small MAC= POWERFUL AF
Pre-renal azotemia causes (reduced GFR)
Heart failure
Sepsis
Renal artery stenosis
=Elevated BUN:Cr ratio and FeNa is less than 2% (greater would be intrinsic)
permeability barrier in the nervous system
Perineurium
Systemic retinoic acid is
CATEGORY X (3-5 weeks and woman don’t even know she Prego) Missing ears or spontaneous abortions
Use of Disulfiram is an example of what type of conditioning
Aversive conditioning (a part of classical conditioning)
Fetal hydantoin syndrome is due to
Maternal use of antiepileptic drugs such as Phenytoin
Antineoplastic agent that is an MAO inhibitor. Patients must avoid dat cheese/tyramine to prevent HTN crisis
Procarbazine
Remember you count up the reflexes:
Achilles reflex: S1 S2
Knee Jerk: L3 L4
Biceps: C5 C6
Triceps: C7 C8
Long-term exercise has been shown to increase cell surface
GLUT-4
IgG anti-RhD antibody that binds to and destroys RhD-positive fetal cells in the maternal circulation
Rhogam
Niacin deficiency (Vitamin B3) = 3D’s
Diarrhea
Dermatitis
Dementia
ADPKD
Polycystin 1 gene = Chromosome 16
Polycystin 2 gene = Chromosome 4
Symptoms: abdominal pain, hematuria, polyuria and nocturia
Berry aneurysms and MVP
DNA is transferred from one bacterium to another (direct cell to cell contact)
Conjugation
Nonsmokers and woman lung cancer
Adenocarcinoma
What ADR do busulfan, amiodarone, methotrexate, Nitrofurantoin, and radiation chest therapy
Pulmonary fibrosis
What two viruses are NK cells most important in fighting
EBV
Herpesviruses
NK cells recognize their lesser amount of MHC I expression
Horizontal nystagmus on lateral gaze at therapeutic levels. Vertical nystagmus, double vision, sedation, and cerebellar ataxia and tremor at supratherapeutic level
Phenytoin
