29 Medication Flashcards
2 drug classifications
1 pharmaceutical class 2 therapeutic class
pharmaceutical class
refers to:
1 mechanism of action [MOA]
2 physiologic effect [PE]
3 chemical structure [CS]
therapeutic class
refers to clinical indication of drug or therapeutic action
ex) analgesic, antibiotic, antihypertensive
pharmacoKINETICS
effects of body on drugs
types of pharmacokinetics
1 absorption
2 distribution
3 metabolism
4 excretion
pharmacoDYNAMICS
effects of drugs on body
- drugs turn on, turn off, promote, or block responses
- can also alter cell structure/environment
types of adverse effects
- allergic rxn
- drug tolerance
- toxic effect
- idiosyncratic effect
- drug interactions: antagonist/synergist
factors affecting drug action
- dvlptl consideration
- weight
- gender
- genetic/cultural
- psychological
- pathology
- environment
- timing of administration
therapeutic range
concentration of drug in the blood serum that produces the desired effect wo toxicity
through level
point when the drug is at its lowest concentration
-indicates rate of elimination
half life
amount of time it takes for 50% of blood concentration of drug to be eliminated fr body
you need a needle for……
parenteral (outside the intestines)
NonParenteral Medications
1 Oral 2 Topical 3 Suppositories 4 Ophthalmic 5 Otic 6 Nasal 7 Inhalation
score pills
pill w grooves to indicate pill may be split
enteric coated
barrier prevents gastric acids in stomach fr dissolving/degrading drugs
DO NOT CUT
extended release, sustained release, time-release, controlled release
coated to dissolve more slowly
capsules
easier to swallow
-CANNOT OPEN TO ADMINISTER
sublingual vs buccal
sublingual goes under tongue
buccal goes bw cheek + gums
DO NOT PROVIDE WATER
elixer vs suspension vs syrup
elixir: alcohol + syrup + water + med
syrup: syrup + water + med
suspension: med + suspension (must shake)
ophthalmic
lean back, block duct, pull undereye, drop into under eye
Liniment
liquid or semi-liquid thats applied to skin w friction + rubbing
Lotion
- meant for external application w/o friction
- less viscous than liniments
- works best w less grease on skin
Oil
contains oil base
Intradermal
administered into dermis right below the epidermis
- 5-15 degrees
- used for sensitivity test + localized anesthesia
which has the longest absorption time out of all parenteral routes?
intradermal injection
how much is the usual intradermal dosage?
0.5mL
usually a small amount
ng tube reasons
1 for suction
2 feeding
Interference
one drug interferes w METABOLISM of another
-leads to build-up of meds and maybe toxicity