29. Adverse Effects of Drugs Flashcards
1
Q
What is pharmacological toxicity?
A
Predictable
Excessive/alternative pharmacological action
2
Q
What is non-pharmacological toxicity?
A
Unpredictable
Due to actions of other drugs
3
Q
What is idiosyncratic toxicity?
A
Dose-independent
Genetic polymorphisms, immunological
Difficult to identify
4
Q
What does API stand for?
A
Active Pharmaceutical Ingredient
5
Q
What should be compared to figure out if a drug is bioequivalent?
A
Area under the curve
Cmax
Confidence interval 0.8
6
Q
What does SmPC stand for?
A
Summary of Product Characteristics
Used to reduce prescribing errors
