32. TCA Cycle Flashcards
1
Q
Step 1 of TCA Cycle
A
Acetyl CoA and oxaloacetate
Release CoA group
Form citrate
2
Q
Step 2 of TCA Cycle
A
Citrate to isocitrate
By removal and addition of a water molecule
3
Q
Step 3 of TCA Cycle
A
Isocitrate is oxidised CO2 is released a-ketoglutarate is left behind NAD+ reduced to NADH Isocitrate dehydrogenase enzyme regulates
4
Q
Step 4 of TCA Cycle
A
a-ketoglutarate oxidised NAD+ reduced to NADH CO2 released CoA added= succinyl CoA regulated by a-ketoglutarate dehydrogenase
5
Q
Step 5 of TCA Cycle
A
CoA of succinyl CoA is swapped for a phosphate group
ADP to ATP
Succinate produced
6
Q
Step 6 of TCA Cycle
A
Succinate oxidised to fumarate
2H+ + FAD = FADH2
7
Q
Step 7 of TCA Cycle
A
Fumarate + H2O = malate
8
Q
Step 8 of TCA Cycle
A
Malate oxidised to oxaloacetate
NAD+ reduced to NADH
9
Q
What activates the TCA Cycle?
A
ADP
Ca++
10
Q
What inhibits the TCA Cycle?
A
ATP, GTP, NADH, Succinyl-CoA
11
Q
What is the maximum number of ATP produced from anaerobic respiration?
A
38
12
Q
Where are the enzymes involved in the TCA Cycle found?
A
Embedded in the inner membrane of the mitochondrion
