20. Agonists Flashcards
1
Q
What is a ligand?
A
Chemical that specifically binds to a receptor
2
Q
What is an agonist?
A
Ligand that binds and causes a biological response
3
Q
What is the dose-response relationship?
A
Tissue response is generally directly proportional to the ratio of receptors occupied with the agonist
4
Q
What is potency?
A
Measure of drug activity
5
Q
What is a partial agonist?
A
One that never produces the max response
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6
Q
What does it mean to have spare receptors?
A
The maximum response has been reached but not all receptors used
7
Q
Name two ways of studying drug interactions
A
- Functional studies
2. Binding studies