25 - sepsis Flashcards
1
Q
def. of SIRS
A
more than 2 of
1. >38 or 90
3. RR>20
WBC>12
2
Q
def. sepsis
A
SIRS due to infection
3
Q
def. severe sepsis
A
sepsis with organ dysfunciton
4
Q
def. septic shock
A
severe sepsis and hypotension
5
Q
common sites of infection in sepsis
A
- lung
- abdo
- urinary
- skin and tissue
6
Q
what to look for on investigations
A
- high WBC
- thrombocytopenia
- lyte abnormalities
- high Hb
- trops
- high lactate
7
Q
other investigations
A
- CXR
- urines
- cultures
8
Q
6 steps to Tx
A
- ABC and monitors
- early, aggressive fluids
- crystalloid through large bore IV - vasopressors
- norepi is best choice - early and approprite ABx
- broad spectrum if not known - pip-tazo with vanco - app. surg
- goal directed therapy
- MAP >65 and urine >0.5mg/kg/hr
9
Q
3 other interventions to think about
A
- ionotropes
- RBC transfusions
- steroids
