21 - diabetic emergencies Flashcards

1
Q

what is triad of DKA

A
  1. hyperglycemia
  2. ketosis
  3. acidosis
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2
Q

what type of DM is DKA primarily in

A

1

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3
Q

2 main patho concepts in DKA

A
  1. relative insulin def.
  2. counter regulatory hormone excess due to failure of normal mechanisms
    - glucagon, catecholamine, cortisol, GH
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4
Q

10 causes of DKA

A
  1. lack of insulin
  2. infection
  3. MI
  4. PE
  5. stroke
  6. pnacreatitis
  7. substance abuse
  8. meds
  9. trauma
  10. surg.
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5
Q

DKA signs and Sx

A

DKA
Diuresis, delirium/dizzy, dehydration
Kussmaul breathing, keto breath
Abdo pain

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6
Q

3 main goals of DKA Tx

A
  1. restore volume
  2. correct lyte imbalance
  3. replensh insulin
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7
Q

what is fluid replacement

A

give half amount lost in first 8 hours

  • 1-2L NS in first hour
  • once glucose falls below 16, change to D5W
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8
Q

when to start giving insulin

A

once K levels reach >3.3 and BP restored

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9
Q

how to dose Kcl

A

based on the levels of K found in the serum

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10
Q

role for bicarb in therapy

A

not one unless pH is

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11
Q

big 3 of DKA Tx

A
  1. fluid resus
  2. glucose control with insulin
  3. correct K
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12
Q

what is dreaded outcome in DKA

A

cerebral edema

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13
Q

what defines hyperosmolar hyperglycemic state (HHS)

A

glucose >33
ph>7.3
bicarb>15
AG320

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14
Q

what is key feature to diff DKA and HHS

A

ketones

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15
Q

how are DKA and HHS diff. in presentation

A

HHS over days to weeks

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16
Q

Tx for HHS

A

same as DKA but no role for bicarb

17
Q

what is whipple’s triad in hypoglycemia

A
  1. low plasma glucose
  2. Sx suggestive of hypoglycemia
  3. prompt resolution when given glucose
18
Q

main causes of hypoglycemia

A
#1 excessive insulin
- alc., sepsis, liver disease
19
Q

2 classes of Sx in hypo

A
  1. autonomin
    - diaphoresis, nausea, hunger, tachy
  2. neuroglycopenic
    - HA, confusion, seiure, coma
20
Q

Tx of hypo

A

prehost- glucose fods

in ER - D50 IV