21 - diabetic emergencies Flashcards
what is triad of DKA
- hyperglycemia
- ketosis
- acidosis
what type of DM is DKA primarily in
1
2 main patho concepts in DKA
- relative insulin def.
- counter regulatory hormone excess due to failure of normal mechanisms
- glucagon, catecholamine, cortisol, GH
10 causes of DKA
- lack of insulin
- infection
- MI
- PE
- stroke
- pnacreatitis
- substance abuse
- meds
- trauma
- surg.
DKA signs and Sx
DKA
Diuresis, delirium/dizzy, dehydration
Kussmaul breathing, keto breath
Abdo pain
3 main goals of DKA Tx
- restore volume
- correct lyte imbalance
- replensh insulin
what is fluid replacement
give half amount lost in first 8 hours
- 1-2L NS in first hour
- once glucose falls below 16, change to D5W
when to start giving insulin
once K levels reach >3.3 and BP restored
how to dose Kcl
based on the levels of K found in the serum
role for bicarb in therapy
not one unless pH is
big 3 of DKA Tx
- fluid resus
- glucose control with insulin
- correct K
what is dreaded outcome in DKA
cerebral edema
what defines hyperosmolar hyperglycemic state (HHS)
glucose >33
ph>7.3
bicarb>15
AG320
what is key feature to diff DKA and HHS
ketones
how are DKA and HHS diff. in presentation
HHS over days to weeks