25 - B) OSTEARTHRITIS DRUGS Flashcards
ANALGESIC AND ANTI-INFLAMMATORY
They have a rapid symptomatic action:
- Paracetamol
- Topical agent: NSAID, capsaicin
- NSAID po, ibuprofen, coxibs
- Opioids: Tramadol
- GLucocorticoids (ia)
SYSADOA
Intraarticular SYSADOA; Hyaluronic acid
SYMPTOMATIC SLOW- ACTING DRUGS FOR OSTEOARTHRITIS
It is an articular lubricant with viscoelastic properties and an anti-inflammatory. The posology is an ia injectiononce a week during 3-5 weeks. The effect last fot 6-12 months.
SYSADOA
Oral SYSADOA: Glucosamine sulphate/ chloride and Chrondroitin sulfate
SYMPTOMATIC SLOW- ACTING DRUGS FOR OSTEOARTHRITIS
It has anti-inflammatory effects to protect the cartilage.Adverse reactions include digestive ones and hypersensitivity.
Glucosamine; diziness, somnoence, descompensation of type II diabetes.
Chondroitin sulfate; coronary edema, renal failure.