10 - B) ANTIMANIAC AND MOOD STABILIZER DRUGS (BIPOLAR D)

Question 1

PROPHYLACTIC TREATMENT

Answer 1

We try to stabilize mood and prevent crisis, often combining drugs. Normally, it was used Lithium, but due to its narrow therapeutic window, there is a recent tendency to substitute it by : Carbamazepine, Valproate, Lamotrigine and Gabapentin.

Question 2

LITHIUM CARBONATE

Answer 2

Prophylactic treatment.

It was used, but due to its narrow therapeutic window, there is a recent tendency to substitute it by : Carbamazepine, Valproate, Lamotrigine and Gabapentin.

PK; BA 100% (oral route), don’t bind plasma proteins, renal excretion (due to the lack of Na+).

Several symtoms are associated: nausea, thirst, hypotension, fine tremor, weight gain, gouy, hypothuroidism. Dehytration at the renal level.

Question 3

CARBAMAZEPINE

Answer 3

Prophylactic treatment.

Question 4

VALPROATE

Answer 4

Prophylactic treatment.

Question 5

LAMOTRIGINE

Answer 5

Prophylactic treatment.

Question 6

GABAPENTIN

Answer 6

Prophylactic treatment.

Question 7

MANIAC CRISIS TREATMENT

Answer 7

OLANZAPINE, RISPERIDONE, QUETIAPINE,
ARIPIPRAZOLE, HALOPERIDOL
Benzodiazepines

Question 8

OLANZAPINE

Answer 8

MANIAC CRISIS TREATMENT

Question 9

RISPERIDONE

Answer 9

MANIAC CRISIS TREATMENT

Question 10

QUETIAPINE

Answer 10

MANIAC CRISIS TREATMENT

Question 11

ARIPIPRAZOLE

Answer 11

MANIAC CRISIS TREATMENT

Question 12

HALOPERIDOL

Answer 12

MANIAC CRISIS TREATMENT

Question 13

Benzodiazepines

Answer 13

MANIAC CRISIS TREATMENT

Question 14

DEPRESSIVE PHASE TRAEATMENT

Answer 14

Typical SRRIs