16 - GENERAL ANAESTHETICS Flashcards
1
Q
GA DRUGS
A
Thre are two tyepes, the administered Iv and those which are administered inhaled.
2
Q
Intravenous anaesthetics
A
They have a very raid action (20s- few minuts). They are used to induce or to mantain anaest hesia (“total iv anaesthesia”- TIVA).
3
Q
`Propofol
A
Its combined with muscle relaxants or analgesic drugs. This is an example of Iv anaesthetic.
4
Q
OPIODS
A
- Opioids. Frequently used in cardiac surgery (stable cardiovascular function or
bradycardia).
Problem: insufficient capacity to depress neuroendocrine function, “stress response”
characterized by an increase in somatotropin, catecholamines, antidiuretic hormone
and cortisol leading to hypertension and effects on the myocardium.
Fentanyl (shorter action compared to morphine, high liposolubility, elimination due to
hepatic metabolism, half-life: 3.5h)
Alfentanyl (half-life : 1.5-2h)
Sufentanyl (half-life: 3h)
Remifentanyl (last generation, ultrarapid action, elimination independent of hepatic
metabolism, half-life: 10min)
15
Use: severe nervous insomnia, certain types of epilepsy, certain psicological
disorders, seizures, anaesthesia - Barbiturates
BDZ increase
5
Q
BARBITURATES
A
Iv anaesthetics- GA
6
Q
Fentanyl
A
a
7
Q
Afentanyl
A
b
8
Q
Sufentanyl
A
c
9
Q
Remifentanyl
A
d
10
Q
Thiopental
A
e
11
Q
Benzodiazepines
A
f
12
Q
Ketamine
A
g
13
Q
Etomidate (corticosteroid)
A
h
14
Q
Droperidol (dehidrobenzioperidol, neuroleptics)
A
i
15
Q
Inhalational anaesthetics- names
A
Nitrous oxide Halothane Enflurane Isoflurane Desflurane Sevoflurane
