15 - LOCAL ANAESTHETICS

Question 1

CNS TOXICITY

Answer 1

I’ts produced after an IV administration by mistake or when the abosoption is too fast at the action site. The problem appears because they cross BBB.
They are going to produce high plasma concentration and depression and excitation secondary due to the inhibition of inhibitory pathways, leading to nausea, vomiting, confusion and convulsions.

Question 2

LA WHICH CAN PRODUCE CNS TOXICITY

Answer 2

PROCAINE > LIDOCAINE= PRILOCINE > LEVOBUPICAINE

Question 3

SYNPTOMS OF CNS TOXICITY BY LA

Answer 3

MOUTH AND TONGUE NUMBESS, ANXIETY, VERBOREA, NYSTAGMMUS AND CONVULSIONS. At T HIGHEST CONCENTRATIONIT LEADS TO RESPIRATORY DEPRESSION THAT CAN PRODUCE DEATH

Question 4

TREATMENT WHEN THERE IS CNS TOXICITY

Answer 4

A

Question 5

CARDIOVASCULAR TOXICITY

Answer 5

A

Question 6

TREATMENT WHEN THERE IS CARDIOVASCULAR TOXICITY

Answer 6

A

Question 7

PROCAINE

Answer 7

A

Question 8

LIDOCAINE

Answer 8

B

Question 9

PRILOCAINE

Answer 9

C

Question 10

LEVOBUPIVACAINE

Answer 10

D

Question 11

ETIDOCAINE

Answer 11

E

Question 12

TETRACAINE

Answer 12

F