2.3 Platelet ultrastructure

Question 1

A bilayer composed of proteins and lipids

Answer 1

Plasma membrane / GLycocalyx

Question 2

Part of plasma membrane where it support platelet activation by supplying arachidonic acid and is converted into TXA2

Answer 2

Phospholipid

Question 3

Part of plasma membrane where it support essential plasma surface-oriented glycosylated receptors

Answer 3

GLycoproteins

Question 4

What is the ligand for:

GP Ia/IIa

a. Collagen
b. vWF
c. Fibrinogen

Answer 4

a

Question 5

What is the ligand for:

GP Ib/IX/V

a. Collagen
b. vWF
c. Fibrinogen

Answer 5

b

Question 6

What is the ligand for:

GP VI

a. Collagen
b. vWF
c. Fibrinogen

Answer 6

a

Question 7

What is the ligand for:

GP IIb/IIIa

a. Collagen
b. vWF
c. Fibrinogen

Answer 7

c

Question 8

A microfilaments and microtubules which maintains cytoskeleton of platelet

Answer 8

Sol-gel zone

Question 9

Sol-gel zone supports the _____ shape of platelets which provides contractile force after activation

Answer 9

Discoid

Question 10

A dense tubular system which sequester Ca2+ for activating platelets

Answer 10

Membranous system

Question 11

Part of Membranous system which is for secretion of alpha granule contents upon platelet activation

Answer 11

Surface connected canalicular system (SCCS)

Question 12

Consitute the mahor portion of platelet cytoplasm

Answer 12

Organelles zone