2.3 Eukaryotic Cell Cycle + Division Flashcards

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1
Q

describe the difference between DNA normally and DNA during cell division

A

normally, DNA is all tangled

during cell divison, DNA condenses and appears as visible chromosomes

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2
Q

describe the process of DNA forming a visible chromosome

A
  1. DNA is a double helix
  2. DNA wraps around histone proteins to form a nucleosome
  3. nucleosome attaches into chromatin
  4. chromatin coils and supercoils and condenses into a visible chromosome
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3
Q

describe, in order, the events of the cell cycle

A
during interphase:
G1- cell assimilates molcules
    - cell grows
S-phase- semi-conservative DNA replication
             -replication of DNA
G2- cell synthesis of more organelles
during mitosis:
prophase
metaphase
anaphase
telophase
cytokinesis
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4
Q

give 4 key points of mitosis

A
  • 2 new daughter cells made
  • genetically identical to parent cells
  • used for growth + replacement
  • asexual reproduction
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5
Q

what happens during interphase in mitosis

A

cellular organelles double in number, the DNA replicates, and protein synthesis occurs. the chromosomes are not visible and the DNA appears as uncoiled chromatin

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6
Q

what happens during prophase in mitosis

A
  • nuclear membrane and nucleolus break down
  • centrioles migrate to opposite poles
  • chromatin condenses to form visible chromosomes
  • spindle fibres start to form
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7
Q

what happens during metaphase in mitosis

A
  • chromosomes attach singly to the equator by centromere

- centromere attaches them on to the spindle fibres

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8
Q

what happens during anaphase in mitosis

A
  • centromeres replicate

- sister chromatids split and move to opposite poles

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9
Q

what happens during telophase in mitosis

A
  • nuclear membrane and nucleolus reform
  • centrioles move away from poles
  • chromatins reform (chromosomes decondense)
  • spindle fibres break down
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10
Q

give 3 ways that growth can be defined as

A

a permanent increase in number of cells
a permanent increase in the mass of an organism
a permanent increase in the size of an organism

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11
Q

what are the three aspects of growth

A

cell division
assimilation
cell expansion

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12
Q

how are worn out or damaged cells replaced

A

by mitosis

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13
Q

describe asexual reproduction

A

involves one parent
no gametes involved
quicker than sexual reproduction
clones are genetically identical to parent
useful for extreme environments or solitary organisms
lots of different methods

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14
Q

describe sexual reproduction

A
requires two parents 
fusion of gametes occurs
gametes are produced by meiosis
more complex organisms
offspring show genetic variation
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15
Q

describe binary fission as a process of asexual reproduction

A

involves mitosis and cytokinesis to make 2 offspring

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16
Q

describe spores as a process of asexual reproduction

A

involves mitosis and production of asexual spores- each spore grows into a new individual

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17
Q

describe regeneration as a process of asexual reproduction

A

some organisms can replace body parts when lost

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18
Q

describe bud production as a process of asexual reproduction

A

outgrowth from parent organism- a smaller, genetically identical organism is produced that then detaches and becomes independent

19
Q

describe new plant structures as a process of asexual reproduction

A

vegetative propagation occurs in flowering plants. a new plant is propagated from the parent

20
Q

is a gamete haploid or diploid

A

haploid

21
Q

define homologous

A

same genes in the same places

22
Q

what are the male gamete and site of production in animals

A

sperm cells in testes

23
Q

what are the male gamete and site of production in plants

A

pollen in anther

24
Q

what are the female gamete and site of production in animals

A

ovum in ovaries

25
Q

what are the female gamete and site of production in plants

A

ovum in ovaries

26
Q

give a summary of the two stages of meiosis

A

MEIOSIS I
normal interphase
different PMAT to mitosis

MEIOSIS II
no S-phase in interphase
no semi-conservative DNA replication
PMAT is the same as mitosis

27
Q

what are the end products of meiosis

A

four genetically identical haploid gametes

28
Q

describe interphase of meiosis I

A

same as mitosis

G1 , s-phase and G2 occur

29
Q

describe prophase of meiosis I

A

nuclear membrane and nucleolus break down
centrioles migrate to opposite poles
chromatin condenses to form visible chromosomes
homologous chromosomes form bivalents
crossing over occurs; where nits of maternal and paternal chromosomes are cut and joined at random points called chiasma

30
Q

describe metaphase of meiosis I

A

independent assortment occurs; either of a pair of homologous chromosomes, maternal or paternal, can move to either pole

31
Q

describe anaphase of meiosis I

A

whole chromosomes move to opposite poles

32
Q

describe telophase of meiosis I

A

centrioles move away from poles
nuclear membrane and nucleolus reform
chromatin reforms
spindle fibres break down

33
Q

describe interphase of meiosis II

A

there is G1 and G2 but no s-phase so no semi-conservative DNA replication occurs

34
Q

describe prophase of meiosis II

A

nuclear membrane and nucleolus break down
centrioles migrate to opposite poles
chromatin condenses to form chromosomes
spindle fibres start to form

35
Q

describe metaphase of meiosis II

A

chromosomes attach singly to the equator by centromere

centromere attaches them on to the spindle fibres

36
Q

describe anaphase of meiosis II

A

centromeres replicate

sister chromatids split and move to opposite poles

37
Q

describe telophase of meiosis II

A

centrioles move away from poles
nuclear membrane and nucleolus reform
chromatin reforms
spindle fibres break down

38
Q

what is a chromosomal mutation

A

a change in the large scale structure of a chromosome

39
Q

describe the effect of a non-disjunction mutation on meiosis

A

during anaphase of meiosis II, the sister chromatids should split and move to opposite poles
in non-disjunction mutations, there is a failure of chromosomes splitting so both chromatids go to one poke

40
Q

what effect does a non-disjunction mutation have on the gametes

A

one gamete will have two copies of a chromosome whereas another gamete will have none.

41
Q

define aneuploidy

A

too little or too many chromosomes

42
Q

give two examples of aneuploidy

A

trisomy

monosomy

43
Q

what are the consequences of a non-disjunction mutation

A

it can be fatal

can cause Down’s syndrome, which is trisomy @ 21st chromosome pair