22 skin (integumentary system) Flashcards
General st5ructure
epidermis
dermis
hypodermis (subcutaneous)
Hypodermis
white adipose and connective tissue
vary in thickness. thick on palms of hands
Hypodermis function
shock absorber
storage
makes hormones
insulator
hypodermis when ageing
causes the wrinkles, more susceptible to hypothermia
Dermis
middle layer
has three layers: papillary and reticular and dermal papillae
dermis function
contains hairs and sweat glands
has sensory structures
gives structures
epidermis
outer most layer 4 or 5 layers depending on thickness held together by adheren junctions has some nerve endings no blood vessels
epidermis frunction
prevents waterloss
deters infection
synthesis of keratin
prevents tissue loss by abrasion
epidermis layers:
top: stratum corneum (horny layer) dead keratinocytes
stratum lucidium: ONLY ON HANDS AND FEET
stratum granulosim: striated squamous epithelium
stratum spinosim: cuboidal epithelium. held together by desmosomes. first time you see golgis appear. keratin production here.
stratum basale: tall columnar cells. constantly renew keratinocytes. produce melanin. produce keratin filaments.
keratin synthesis
from basal layer start tp differentiate to lamianr bodies the granular cells then theres a water barrier then cells start to die by apoptosis and form keratin.
epidermis keratin transit time from basal layer
normal: 28-40 days
psoriasis: 2-3 days
hyperkeratosis: laid down too much keratin
other cells in epidermis (there’s 3)
melaocytes: occur at intervals 1 in 8. produce melanin
langerhans cells:antigen presentation and what not
merkal cells: associated with sensory nerve endings 10% of cells in the epidermis.
four types of skin:
hairy
non hairy
thick
thin
types of hair (there’s 3)
lanugo: covers the developing fetus
vellus: short thin light colour not connected to sebaceous gland
terminal: head, eyebrows, genitalia, armpits. produced by action of testosterone.
mechanoreceptors
number of different ones that register pain, temperature, vibrationa, touch, texture