2016 34 Postmenopausal Ovarian Cysts Flashcards
- What is important in the history of postmenopausal ovarian cysts? *
- Risk factors
- Symptoms suggestive of malignancy
- Family history of ovarian, bowel or breast cancer
- IBS symptoms within last 12 months
- What should examination include for postmenopausal ovarian cysts? *
- BMI
- Abdo for ascites & features of palpable mass
- VE
- What is the role of Ca-125 in postmenopausal ovarian cysts? *
- Only serum tumour marker
- Don’t use in isolation, normal value does not exclude cancer
- Not enough evidence for other tumour markers
- What imaging should be used to characterise postmenopausal ovarian cysts? *
- TVUS
- TAUS supplementary if too large for TVUS
- Clearly document morphological findings & subjective assessment
- What imaging should not be used to characterise postmenopausal ovarian cysts? *
- Colour flow Doppler
- Spectral & pulse Doppler indices
- 3D ultrasound
- CT (until diagnosis indicated)
- MRI (2nd line if US inconclusive)
- PET-CT
- Which postmenopausal cysts can be managed conservatively? *
Must meet all conditions:
1. RMI < 200
2. Asymptomatic
3. Simple cyst
4. < 5cm
5. Unilocular
6. Unilateral
- What does conservative management of postmenopausal ovarian cysts involve? *
- Repeat Ax in 4-6 months
- Discharge if resolved
- Repeat again if unchanged
- Consider discharge at 1 year
- Consider intervention if features change
- In which postmenopausal ovarian cysts is BSO considered? *
- RMI < 200
ANY of the following features: - Symptomatic
- Non-simple features
- > 5cm
- Multilocular
- Bilateral
- How are postmenopausal ovarian cysts with an RMI > 200 managed? *
- CTAP
- Referral to gynae-onc MDT
- How are postmenopausal ovarian cysts with an RMI > 200 managed? *
- CTAP
- Referral to gynae-onc MDT
- How are postmenopausal cysts with high suspicion of malignancy following MDT managed? *
- Laparotomy
- Full staging procedure
- By gynae-oncologist
- How are postmenopausal ovarian cysts with a low suspicion of malignancy following MDT managed? *
- Laparotomy
- Pelvic clearance: TAH + BSO + omentectomy + peritoneal cytology
- By a gynaecologist
- How is RMI-I calculated? *
- U x M x Ca-125
- U scored 0 (no features) 1 (1) or 3 (2-5)
- M scores 1 for premenopausal, 3 for postmenopausal
- What are the ultrasound features that score on RMI-I? *
- Multilocular
- Solid areas
- Metastases
- Ascites
- Bilateral lesions
- What are the ultrasound features that score on RMI-I? *
- Multilocular
- Solid areas
- Metastases
- Ascites
- Bilateral lesions
What is the incidence of ovarian cysts in postmenopausal women?
5-17%
What is the incidence of ovarian cysts in postmenopausal women?
5-17%
What postmenopausal ovarian cysts are insignificant & don’t need following up?
<1cm
What examination findings of a postmenopausal custard associated with malignancy?
- Irregularity
- Solid consistency
- Fixed, immobile
- Nodularity
- Bilaterality
- Ascites
What non-malignant conditions can increase Ca-125 level?
- PID
- Fibroids
- Acute benign cyst accidents
- Endometriosis
- Non-gynae causes of peritoneal irritation
What are the ultrasound features of a simple cyst?
- round or oval shape
- thin or imperceptible wall
- posterior acoustic enhancement
- anechoic fluid
- absence of septations or nodules
What are the ultrasound features of a complex ovarian cyst?
- Complete separation/multilocular
- Solid nodules
- Papillary projections
What are the sensitivity & specificity of RMI-I score > 200?
Sensitivity: 78%
Specificity: 87%
What are the IOTA B-rules for ovarian cysts?
- Unilocular
- Solid components, largest <7mm
- Acoustic shadowing
- Smooth multilocular with largest diameter < 100mm
- No blood flow on colour Doppler
What are the M-rules for ovarian cysts?
- Irregular solid tumour
- Ascites
- At least 4 papillary structures
- Irregular multilocular with largest diameter > 100mm
- Prominent blood flow on colour Doppler
Why is aspiration of cysts not recommended in postmenopausal women?
- Poor at distinguishing benign vs malignant
- Often not therapeutic
- May índice spillage & seeding