20 - Cellular organization (DLA) Flashcards
What are the main components of the membrane?
Lipids and proteins
Lipids are Am…
Amphipathic
- Hydrophilic
- Hydrophobic
3 major classes of lipids?
Phospholipids
Cholesterol
Glycolipids
2 major classes of proteins?
Integral - embedded in or pass through the lipid bilayer
Peripheral - associate with integral membrane proteins
What is the most abundant membrane lipid?
Phospholipid
What affects the membrane fluidity?
Cholesterol
Glycolipids account for what % of the lipid molecules?
5%
6 categories of integral membrane proteins?
Pumps, Receptors, Channels, Linkers, Enzymes, Structural proteins
What is a carbohydrate rich zone and helps establish the microenvironment at the cell surface?
Glycocalyx
What does the Glycocalyx do for cell to cell interaction?
Lectins - carb binding proteins
What is the fluid mosaic model?
lipids and proteins have the ability to move on the plane
What stabilizes the membrane?
Cholesterol by reducing membrane fluidity
What is permeable through the membrane?
hydrophobic, non-polar, uncharged (02 and CO2)
What is not permeable through the membrane?
Polar and charged,
Exocytosis
Substance exits the cells by a vesicle