2. STRUCTURE & FUNCTIONS IN LIVING ORGANISMS Flashcards

2.1 - 2.59B

2
Q

2.1 cells contain a number of o_________

A

organelles

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3
Q

2.1 organelles are

A

structures that carry out specific processes the cell needs to survive

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4
Q

2.1 tissues are

A

groups of similar cells

that work together to carry out the same function

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5
Q

2.1 an example of tissue in humans is

A

muscle tissue

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6
Q

2.1 organs are made up of

A

several different tissues

working together to carry out a more complex function

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7
Q

2.1 an example of an organ in a human is

A

the heart

(muscle is one of the tissues making up the heart)

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8
Q

2.1 organ systems are made up of

A

several different organs working together to carry out a complex function essential to life

e.g. circulating blood around the body

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9
Q

2.1 organelle ->

A

cell

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10
Q

2.1 cell ->

A

tissue

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11
Q

2.1 tissue ->

A

organ

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12
Q

2.1 organ ->

A

organ system

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13
Q

2.1 organ system ->

A

organism

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14
Q

2.1 organelle ->

c , t , o , o & o

A

cell, tissue, organ, organ system & organism

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15
Q

2.2 cells are separated from their surrounding environment by

A

a cell membrane

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16
Q

2.2 within the cell membrane is the

A

cytoplasm

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17
Q

2.2 eukaryotic cells have … contained within their cytoplasm

A

organelles

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18
Q

2.2 organelles are

A

where specific processes take place within the cell

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19
Q

2.2 what is in the cytoplasm of a eukaryotic cell

A

nucleus, mitochondria & ribosomes

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20
Q

2.2 plant cells contain the following additional structures

A

cell wall, chloroplasts & a vacuole

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21
Q

2.3 function of the nucleus

A

contains genetic material in chromosomes
controls cell division

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22
Q

2.3 function of the cytoplasm

A

supports cell structure
site of many chemical reactions
contains water and many solutes
jelly-like substance

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23
Q

2.3 function of the cell membrane

A

holds the cell together
controls substances entering and leaving the cell

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24
Q

2.3 function of the cell wall

A

gives the cell extra support and defines its shape

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25
Q

2.3 function of the mitochondria

A

site of aerobic respiration providing energy for the cell

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26
2.3 function of the chloroplasts
site of photosynthesis - provides food for plants chlorophyll pigment absorbs light energy
27
2.3 function of the ribosomes
the site of protein synthesis
28
2.3 function of the vacuole
contains cell sap used for storage helps support the shape of the cell
29
2.4 how many structures does a plant cell have
8
30
2.4 how many structures does an animal cell have
5
31
2.4 in addition to the structures an animal cell has, a plant cell also has
chloroplasts, a (cellulose) cell wall and a vacuole
32
2.4 what does an animal cell have
a nucleus, cell membrane, mitochondria, ribosomes and a cytoplasm
33
2.4 what does a plant cell have
a nucleus, cell membrane, mitochondria, ribosomes, cytoplasm, chloroplasts, cell wall and a vacuole
34
2.5B what is cell differentiation
the process by which a cell changes to become specialised
35
2.5B what happens when a cell differentiates
the cells develop the structure & characteristics needed to carry out their functions
36
2.5B when does cell differentiation occur
as an organism develops
37
2.5B give examples of cell differentiation to form specialised cells
nerve cells, red blood cells, root hair cells & palisade mesophyll cells
38
2.6B advantages of stem cells in medicine
- can treat a wide variety of diseases - organs develop from a patient's own stem cells which reduces risk of organ rejection & wait from a donor - stem cell technology can repair damaged organs by growing new tissue from stem cells
39
2.6B disadvantages of stem cells in medicine
- stem cells cultured in a lab could be infected with a virus that could transmit to a patient - risk of cultured stem cells accumulating mutations that can lead to cancer developing - a low number of stem cell donors
40
2.7 the chemical elements present in carbohydrates
carbon, hydrogen and oxygen (C,H,O)
41
2.7 the chemical elements present in proteins
carbon, hydrogen, oxygen and nitrogen (C,H,O,N)
42
2.7 the chemical elements present in lipids (fats&oils)
carbon, hydrogen and oxygen (C,H,O)
43
2.8 starch and glycogen is from
simple sugars
44
2.8 protein is from
amino acids
45
2.8 lipids are from
fatty acids and glycerol
46
2.8 a monosaccharide is a ...
simple sugar like glucose
47
2.8 a disaccharide is made when
two monosaccharides join together e.g. maltose = glucose & glucose sucrose = glucose & fructose
48
2.8 a polysaccharide is formed when
lots of monosaccharides join together
49
2.8 polysaccharides starch, glycogen or cellulose are all formed when
lots of glucose molecules join together
50
2.8 most fats (lipids) in the body are made up of
triglycerides
51
2.8 lipids basic unit is
one glycerol molecule chemically bonded to three fatty acid chains
52
2.8 proteins are formed from
long chains of amino acids
53
2.8 when amino acids are joined together
a protein is formed
54
2.9 what is the test for starch?
iodine solution
55
2.9 explain the test for starch
1. place food sample on a spotting tile 2. add a few drops of iodine solution to the sample 3. blue - black colour indicates starch
56
2.9 what is the test for glucose / reducing sugars?
benedicts solution
57
2.9 explain the test for glucose / reducing sugars?
1. place food sample in a boiling tube 2. add benedict’s solution to the sample of food in solution 3. place in a water bath at 80*c for 5 minutes 4. a change from blue to brick red if present (if green, yellow or orange means less sugar present)
58
2.9 what is the test for protein?
biuret test
59
2.9 explain the test for protein
1. place food sample in a boiling tube 2. add enough biuret solution for colour to be pale blue 3. if protein is present colour will change to mauve / purple
60
2.9 what is the test for lipids?
emulsion test
61
2.9 explain the test for lipids?
1. place food sample in a test tube 2. add small amount of ethanol and shake to dissolve any lipid in the alcohol. 3. add equal volume of water 4. cloudy white colour (emulsion will form) indication presence of lipid
62
2.9 benedicts solution is used to test for
reducing sugars (glucose)
63
2.9 benedicts solution colour change
blue to brick red
64
2.9 how do I remember benedicts solution
christmas sugar
65
2.9 iodine is used to test for
starch
66
2.9 iodine solution colour change
orange to blue-black
67
2.9 how do I remember iodine
bumblebee
68
2.9 biuret is used to test for
protein
69
2.9 biuret solution colour change
(light)blue to pale purple
70
2.9 how do I remember biuret
snowflakes (et) proTEin biurET
71
2.9 emulsion is used to test for
lipids
72
2.9 emulsion colour change
colourless to a cloudy white emulsion
73
2.9 how do I remember emulsion
snowing
74
2.10 enzymes are biological
catalysts
75
2.10 a catalyst is a ........
chemical which increases the rate of a reaction without being used up itself in the reaction
76
2.10 the theory for understanding how enzymes work is the
lock and key theory
77
2.10 what is the lock and key theory
the substrate and enzyme collide, the substrate binds to the active site of the enzyme, (the reaction occurs by an alternative pathway with a lower activation energy) once the reaction occurs, the products don't fit - so they are released, the enzyme is free to catalyse the next reaction
78
2.10 the active site has a particular shape which is ... to the shape of the substrates
complementary
79
2.10 because the shape of the active site is complementary to that of the substrates, this means
each enzyme can only catalyse one reaction
80
2.11 as temperature increases the enzyme & substrate have more
kinetic energy so they move faster and there are more successful collisions
81
2.11 high temperatures and changes of pH cause the shape
to change
82
2.11 when the shape changes we say this is
the protein being denatured
83
2.11 when the active site changes shape it is no longer
complementary to the substrate
84
2.12 practical for investigating effect of temperature on enzymes
place spots of iodine into each dip of a spotting tile add 5cm^3 of starch suspension into a boiling tube w/ a syringe with a different syringe add 5cm^3 of amylase solution into another tube fill a beaker w/ water at 20*C & place both boiling tubes inside for 5 minutes pour amylase solution into the starch suspension leaving it in the water bath take a sample w/ pipette & add a drop to the iodine solution in the spotting tile record colour change of the solution in the tile repeat every 30 seconds for 10 minutes until the iodine solution remains orange indicating the starch is used up repeat the experiment with the water bath at diff temps between 20*C & 60*C
85
2.13 what is the optimum pH for most enzymes
7
86
2.13 which enzymes have a lower pH than 7
those produced in acidic conditions e.g. the stomach - pH 2
87
2.13 which enzymes have a higher pH than 7
those produced in alkaline conditions e.g. the duodenum - pH 8/9
88
2.13 what happens if the pH is too high or too low
the bonds that hold the amino acid chain together can be disrupted / destroyed this changes the shape of the active site so the substrate can no longer fit into it this reduces the rate of activity moving too far away from the pH - the enzyme will denature
89
2.14B practical investigating how enzyme activity can be affected by changes in pH
add a drop of iodine to each well of a spotting tile use a syringe to place 2cm^3 of amylase into a test tube add 1cm^3 of buffer solution (at pH2) to the same test tube using a syringe in another test tube add 2cm^3 of starch solution pour the starch solution into the amylase and buffer solution start a stopwatch whilst mixing the solution using a pipette every 10 seconds transfer a droplet of the solution to a new well of iodine solution which should turn blue black repeat every 10 seconds until the iodine solution stops turning blue-black meaning the amylase has broken down all the starch record the time taken for reaction to be completed repeat the investigation with buffers at different pH values from pH3 - pH7
90
2.14B practical amylase is an enzyme that breaks down
starch into maltose
91
2.14B practical what does it mean when the iodine solution remains orange - brown
that all the starch has broken down
92
2.14B practical what will this investigation show
at the optimum pH the iodine stopped turning blue-black within the shortest amount of time
93
2.14B practical why does the iodine remain orange in the shortest amount of time
because the enzyme is working at its fastest / optimum rate and has digested all of the starch
94
2.14B practical what will happen at a higher or lower pH
the iodine will take longer to stop turning blue-black
95
2.14B practical what is a control variable
the starch and amylase solutions should be placed in a water bath at the optimum temperature before being used
96
2.14B practical name one tool that can be used to measure the progress of the reaction more accurately
using a colorimeter
97
2.14B practical CORMS
C - changing the pH of the environment O - not relevant - no organism R - repeat several times to ensure reliability M - measure time taken for iodine to stop turning blue-black S - control the concentration & volume of the amylase, iodine and starch solution
98
2.15 definition of diffusion
the random movement of particles from an area of higher concentration to an area of lower concentration
99
2.15 definition of osmosis
the net diffusion of free water molecules from an area of high water concentration to an area of low water concentration across a partially permeable membrane
100
2.15 osmosis in cell: what is: solution outside cell has same water potential as inside cell - no net movement
isotonic solution (animal = normal) (plant = flaccid)
101
2.15 osmosis in cell: what is: solution outside cell has higher water potential then inside cell - net movement of free water molecules into cell
hypotonic solution (animal = lysed) (plant = turgid)
102
2.15 osmosis in cell: what is: solution outside cell has lower water potential then inside cell - net movement of free water molecules out of cell
hypertonic solution (animal = shrivelled) (plant = plasmolysed)
103
2.15 definition of active transport
movement of molecules from an area of low concentration to an area of high concentration using ATP
104
2.16 the four main factors that affect the rate of movement
surface area to volume ratio, distance, temperature and concentration gradient
105
2.16 why is a larger surface area a good thing
it quickens the rate at which substances can move across its surface
106
2.16 example of large surface area
highly folded surface of the small intestine increases its surface area
107
2.16 why is a shorter distance a good thing
the smaller the distance molecules have to travel, the faster the transport will occur
108
2.16 example of short diffusion distance
alveoli walls are one cell thick - rate of diffusion across them is as fast as possible
109
2.16 why is higher temperature a good thing
the higher the temperature, the faster molecules move as they have more energy
110
2.16 how is higher temp a good thing
because there are more collisions against the cell membrane and therefore a faster rate of movement across them
111
2.16 why is a greater difference in a concentration gradient a good thing
the greater the difference in concentration on either side of the membrane, the faster movement across it will occur
112
2.16 how is a greater difference in a concentration gradient a good thing
because the on the side with the higher concentration, more random collisions against the membrane will occur
113
2.17 practical: investigating diffusion
coloured agar is made from indicators coloured agar is cut into required dimensions calculate the surface area, SA:V R and volume and record it cubes placed in boiling tubes of different solutions (same volume of it) ^^^ e.g. dilute hydrochloric acid measurements taken of time for cube to completely change colour of indicator can draw a graph of rate of diffusion (rate of colour change) changes with surface area : volume ratio of agar cubes
114
2.17 practical: investigating osmosis
prepare a range of sucrose (sugar) solutions ranging from 0 Mol/dm3 (distilled water) to 1 mol/dm3 set up 6 labelled test tubes with 10cm3 of each of the sucrose solutions using the knife, cork borer and ruler, cut 6 equally-sized cylinders of potato blot each one with a paper towel and weigh on the balance put 1 piece into each concentration of sucrose solution after 4 hours, remove them, blot with paper towels and reweigh them
115
2.18 process of photosynthesis
energy from sunlight is absorbed by chlorophyll, a green pigment found inside chloroplasts green plants use this energy to make the carbohydrate glucose from the raw materials carbon dioxide and water at the same time, oxygen is made and released as a waste product
116
2.19 word and balanced chemical equations for photosynthesis
carbon dioxide + water -> glucose + oxygen 6CO2 + 6H2O -> C6H12O6 + 6O2
117
2.20 how does varying temperature affect the rate of photosynthesis
it affects how much kinetic energy the particles have so affects the speed at which carbon dioxide and water move more successful collisions (too high temp can denature enzymes that control the process of photosynthesis)
118
2.20 how does varying light intensity affect the rate of photosynthesis
the intensity of the light available to the plant will affect the amount of energy that it has to carry out photosynthesis the more light a plant receives, the faster the rate of photosynthesis
119
2.20 how does varying carbon dioxide concentration affect the rate of photosynthesis
carbon dioxide is one of the raw materials required for photosynthesis this means the more carbon dioxide that is present, the faster the reaction can occur
120
2.21 structure of waxy cuticle
protective layer on top of the leaf prevents water from evaporating
121
2.21 structure of upper epidermis
thin and transparent to allow light to enter palisade mesophyll layer underneath
122
2.21 structure of palisade mesophyll
column shaped cells tightly packed with chloroplasts to absorb more light maximising photosynthesis
123
2.21 structure of spongy mesophyll
internal air spaces which increase surface area to volume ratio for the diffusion of gases (mainly carbon dioxide)
124
2.21 structure of lower epidermis
contains guard cells and stomata
125
2.21 structure of guard cell
absorbs and loses water to open and close stomata to allow carbon dioxide to diffuse in oxygen to diffuse out
126
2.21 structure of stomata
where gas exchange takes place opens during day closes during night evaporation of water takes place here found in much greater concentration on underside of leaf to reduce water loss (in most plants)
127
2.21 structure of vascular bundle
contains xylem and phloem to transport substances to and from the leaf
128
2.21 structure of xylem
transports water into leaf for mesophyll cells to use in photosynthesis and for transpiration from stomata
129
2.21 structure of phloem
transports sucrose and amino acids around the plant
130
2.21 what are all the 10 leaf structures
waxy cuticle, upper epidermis, palisade mesophyll, spongy mesophyll, lower epidermis, guard cell, stomata, vascular bundle, xylem and phloem
131
2.21 adaptation of large surface area (leaf)
increases surface area for the diffusion of carbon dioxide and absorption of light for photosynthesis
132
2.21 adaptation of being thin
allows carbon dioxide to diffuse to palisade mesophyll cells quickly
133
2.21 adaptation of chlorophyll
absorbs light energy so that photosynthesis can take place
134
2.21 adaptation of network of veins
allows the transport of water to the cells of the leaf and carbohydrates from the leaf for photosynthesis (water for photosynthesis) (carbohydrates - product of photosynthesis)
135
2.21 adaptation of stomata
allows carbon dioxide to diffuse into the leaf and oxygen to diffuse out
136
2.21 adaptation of epidermis being thin and transparent
allows more light to reach the palisade cells
137
2.21 adaptation of thin cuticle made of wax
to protect the leaf without blocking sunlight
138
2.21 adaptation of palisade cell layer at top of leaf
maximises the absorption of light as it will hit chloroplasts in the cells directly
139
2.21 adaptation of spongy layer
air spaces allow carbon dioxide to diffuse through the leaf increasing surface area
140
2.21 adaptation of vascular bundles
thick cell walls of the tissue in the bundles help to support the stem and leaf
141
2.21 specialised leaf for photosynthesis: large surface area and thin
to maximise absorption of sunlight and increases number of stomata so carbon dioxide can diffuse faster
142
2.21 specialised leaf for photosynthesis: upper epidermis
transparent allowing light to penetrate to the mesophyll
143
2.21 specialised leaf for photosynthesis: palisade cells
long thin and tightly packed w large numbers of chloroplasts main site of photosynthesis
144
2.21 specialised leaf for photosynthesis: stomata
allows gases to diffuse into air spaces of the leaf - short diffusion distance for carbon dioxide
145
2.21 specialised leaf for photosynthesis: xylem transporting water
water that's absorbed in the roots into the leaves so short distance for water to diffuse into cells
146
2.21 specialised leaf for photosynthesis: phloem vessels
phloem vessels transport sugars made in photosynthesis to other parts of plant
147
2.22 plants requires what for growth
mineral ions
148
2.22 chlorophyll requires what to be made
magnesium ions
149
2.22 amino acids require what to be made (so proteins & nucleic acids - DNA & RNA)
nitrate ions
150
2.23 practical: investigate photosynthesis
take a bundle of shoots of a water plant submerge them in a beaker of water underneath an upturned funnel fill a boiling tube with water and place it over the end of the funnel as oxygen is produced, the bubbles of gas will collect in the boiling tube and displace the water show that the gas collected is oxygen by relighting a glowing splint
151
2.23 practical: investigating production of starch & photosynthesis&light
de-starch the plant by placing it in a dark cupboard for 24 hours (this ensures that any starch already present in the leaves will be used up) partially cover a leaf of the plant with aluminium foil and place the plant in sunlight for a day remove the covered leaf and test for starch using iodine: drop the leaf in boiling water (kills the tissue and breaks down the cell walls) transfer the leaf into hot ethanol in a boiling tube for 5-10 minutes (removes the chlorophyll so colour changes from iodine are more clear) rinse the leaf in cold water to soften the leaf tissue spread the leaf out on a white tile and cover it with iodine solution the entire leaf will turn blue-black as photosynthesis is occurring in all areas of the leaf proving light is necessary for photosynthesis and production of starch
152
2.23 practical: CORMS evaluation on light & photosynthesis
C - We are changing whether there is light or no light O - The leaves will be taken from the same plant or same species, age and size of the plant R - We will repeat the investigation several times to ensure our results are reliable M1 - We will observe the colour change of the leaf when iodine is applied M2 - ...after 1 day S - We will control the temperature of the room
153
2.23 practical: carbon dioxide & photosynthesis
de-starch the plant by placing it in a dark cupboard for 24 hours following destarching, enclose 1 leaf with a conical flask containing potassium hydroxide potassium hydroxide will absorb carbon dioxide from the surrounding air enclose another leaf with a conical flask containing no potassium hydroxide (control experiment) place the plant in bright light for several hours test both leaves for starch using iodine solution drop the leaf in boiling water transfer the leaf into hot ethanol in a boiling tube for 5-10 minutes rinse the leaf in cold water spread the leaf out on a white tile and cover it with iodine solution the leaf from the conical flask containing potassium hydroxide will remain orange-brown - couldn't photosynthesise due to lack of carbon dioxide the leaf from the conical flask not containing potassium hydroxide should turn blue-black as it had all necessary requirements for photosynthesis
154
2.23 practical: CORMS evaluation carbondioxide & photosynthesis
C - We are changing whether there is carbon dioxide or no carbon dioxide O - The leaves will be taken from the same plant or same species, age and size of plant R - We will repeat the investigation several times to ensure our results are reliable M1 - We will observe the colour change of the leaf when iodine is applied M2 - ...after 1 day S - We will control the temperature of the room and the light intensity
155
2.23 practical: investigating chlorophyll & photosynthesis
drop the leaf in boiling water This kills the tissue and breaks down the cell walls transfer the leaf into hot ethanol in a boiling tube for 5-10 minutes this removes the chlorophyll so colour changes from iodine can be seen more clearly rinse the leaf in cold water this is done to soften the leaf tissue after being in ethanol spread the leaf out on a white tile and cover it with iodine solution the white areas of the leaf contain no chlorophyll and when the leaf is tested only the areas that contain chlorophyll stain blue-black the areas that had no chlorophyll remain orange-brown as no photosynthesis is occurring here and so no starch is stored
156
2.23 practical: CORMS evaluation for chlorophyll and photosynthesis
C - We are changing whether there is chlorophyll or no chlorophyll O - The leaves will be taken from the same plant or same species, age and size of the plant R - We will repeat the investigation several times to ensure our results are reliable M1 - We will observe the colour change of the leaf when iodine is applied M2 - ...after 1 day S - We will control the temperature of the room and the light intensity
157
2.24 what are the key food groups are for a balanced diet
carbohydrates proteins lipids dietary fibre vitamins minerals (mineral ions) water
158
2.25 carbohydrates what food source what function
bread, potatoes, rice, cereals & fruit fuel for respiration source of energy
159
2.25 proteins what food source what function
meat, eggs, fish, quinoa & quorn growth and repair of cells and tissues fuel for respiration
160
2.25 lipids (fats) what food source what function
butter, oil, nuts, cream & avocados store of energy thermal (and electrical) insulation fuel for respiration
161
2.25 dietary fibre what food source what function
vegetables, whole grains provides bulk for the intestine to push food through it
162
2.25 vitamins what food source what function
fruits and vegetables needed in small quantities to maintain health
163
2.25 minerals what food source what function
fruits and vegetables, meats, dairy products needed in small quantities to maintain health
164
2.25 water what food source what function
water, juice, milk, fruits & vegetables needed for chemical reactions to take place in cells
165
2.25 calcium what food source what function
milk, cheese, eggs for strong teeth and bones (involved in the clotting of blood) deficiency leads to osteoporosis later in life
166
2.25 vitamin D what food source what function
oily fish, dairy products (also made naturally by body in sunlight) helps body to absorb calcium & required for strong bones and teeth
167
2.25 vitamin C what food source what function
citrus fruits, strawberries, green vegetables forms an essential part of collagen protein - makes up skin, hair, gums & bones deficiency causes scurvy
168
2.25 vitamin A what food source what function
meat, liver, dairy, leafygreen vegetables (spinach), eggs needed to make the pigment in the retina for vision
169
2.25 iron what food source what function
red meat, liver, leafygreen vegetables (spinach) needed to make haemoglobin ^ pigment in redbloodcells that transports oxygen
170
2.26 energy requirements for age
the amount needed in young people increases towards adulthood - energy is needed for growth children need a higher proportion of protein than adults for growth energy for adults decrease as they age
171
2.26 energy requirements for activity levels
the more active, the more energy required for movement as muscles are contracting more and respiring faster
172
2.26 energy requirements for pregnancy
requirements increase as energy is needed to support the growth of the developing foetus extra calcium & iron are needed to help build the bones, teeth and blood of the foetus
173
2.27 function of the mouth
where mechanical digestion takes place teeth chew food - smaller pieces amylase enzymes in saliva digest starch into maltose shaped into bolus so it can be swallowed
174
2.27 function of the oesophagus
connects mouth to the stomach contractions take place to push bolus down
175
2.27 function of the stomach
food's mechanically digested by churning protease enzymes chemically digest proteins hydrochloric acid kills bacteria & optimum pH for protease enzymes to work
176
2.27 function of the small intestine (duodenum)
food coming out stomach finishes being ^ - digested by enzymes produced here & also secreted from the pancreas ! slightly alkaline pH 8-9
177
2.27 function of the small intestine (ileum)
where absorption of digested food - molecules takes place long & lined with villi - increasing surface - area where absorption can take place ! slightly alkaline pH 8-9
178
2.27 function of the large intestine (colon & rectum)
water is absorbed from remaining material in the COLON to produce faeces faeces is stored in the rectum and removed through the anus
179
2.27 function of the pancreas
produces amylase, protease & lipase secretes enzymes is an alkaline fluid into the duodenum(LARGEint) to raise pH of fluid coming out of the stomach
180
2.27 what are the 6 structures in the alimentary canal
mouth, oesophagus, stomach, small intestine, large intestine & pancreas
181
2.27 the stages of food breakdown
ingestion - taking in substances, mechanical digestion - breaking food into smaller pieces chemical digestion - large, insoluble molecules broken down into small, soluble molecules absorption - movement of small food molecules and ions through the wall of the intestine into the blood assimilation - movement of digested food molecules into body where they are used, becoming part of the cells egestion - passing out undigested or unabsorbed food (as faeces) through the anus
182
2.28 how is food moved through the gut by peristalsis
muscles in the walls of the oesophagus create waves of contractions - forcing the bolus along once the bolus has reached the stomach, it turns into chyme - continues on to the small intestine peristalsis is controlled by circular & longitudinal muscles mucus is produced to continually lubricate the food mass and reduce friction dietary fibre provides the roughage required for the muscles to push against during peristalsis
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2.28 what mechanism pushes food through the gut
peristalsis
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2.29 protein ——>
protein —(pepsin)—> [peptides] —(trypsin)—> amino acids
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2.29 (carbohydrates?) starch ——>
(carbohydrates?) starch —(amylase)—> [maltose] —(maltase)—> glucose
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2.29 lipids ——>
lipids —(lipase)—> glycerol & fatty acids
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2.29 what enzyme breaks down protein into peptides what enzyme breaks down peptides amino acids
protease: pepsin pepsin is made in the stomach protease: trypsin trypsin is made in the pancreas & small intestine
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2.29 what enzyme breaks down carbohydrates into maltose what enzyme breaks down maltose into glucose
carbohydrase: amylase amylase is made in pancreas and salivary glands carbohydrase: maltase maltase is made in pancreas
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2.29 what enzyme breaks down lipids into fatty acids and glycerol
lipase: lipase enzymes lipase enzymes are produced in the pancreas
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2.30 where is bile produced
in the liver
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2.30 where is bile stored
in the gall bladder
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2.31 what does bile do to stomach acid
it neutralises the hydrochloric stomach acid
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2.31 what does bile do to lipids
it emulsifying lipids
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2.31 how does bile neutralise stomach acid
the alkaline properties in it allow it to neutralise the hydrochloric acid the neutralisation is essential as enzymes in small intestine have higher optimum pH
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2.31 how does bile emulsify lipids
it breaks apart large drops of fat into smaller ones (increasing their surface area)
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2.32 how is the small intestine adapted for absorption
it is very long and has a highly folded surface with millions of villi which increase the surface area allowing absorption to take place faster and more efficiently peristalsis helps by mixing food and enzymes and keeping things moving
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2.32 how is the structure of a villus adapted for absorption
a large surface area: microvilli on the surface short diffusion distance: one cell thick walls steep concentration gradient: - surrounded by a network of blood capillaries - transport glucose&amino acids away - a lacteal to transport fatty acids and glycerol away
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2.33B practical: energy content of a food sample practical:
measure 25cm3 of water pour into boiling tube record starting temp food is lit over bunsen burner hold food under boiling tube to heat it (if food stops burning relight it) relight until food no longer burns measure finishing temp of water calculate the temp change
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2.34 how does the process of respiration produce ATP
energy is released from glucose either in the presence of oxygen (aerobic) or no oxygen (anaerobic) resulting in the production of carbon dioxide and water as waste products energy is transferred in the form of ATP
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2.35 what does ATP provide for cells
ATP provides energy for cells (muscle contractions & keeping warm - painting a constant temperature)
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2.36 differences between aerobic & anaerobic respiration with oxygen
aerobic needs oxygen anaerobic doesn't need oxygen
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2.36 differences between aerobic & anaerobic respiration with the breakdown of glucose
breakdown is complete in aerobic breakdown is incomplete in anaerobic
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2.36 differences between aerobic & anaerobic respiration with the products
aerobic = carbon dioxide & water anaerobic = anima cells: lactic acid yeast: carbon dioxide & ethanol
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2.36 differences between aerobic & anaerobic respiration with the energy released
aerobic releases a lot of energy anaerobic releases a little
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2.37 word equation for aerobic respiration
glucose + oxygen → carbon dioxide + water
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2.37 the balanced chemical symbol equation for aerobic respiration
C6H12O6 + 6O2 → 6CO2 + 6H20
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2.38 the word equation for anaerobic respiration in animals
glucose ---> lactic acid
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2.38 the word equation for anaerobic respiration in plants
glucose ---> ethanol + carbon dioxide
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2.39 practical: evolution of carbon dioxide from respiring seeds
measure out 10 cm3 of hydrogencarbonate indicator into 3 boiling tubes put in a layer of cotton wool place 10 germinating seeds in tube A place 10 boiled/dead seeds in tube B place 10 glass beads in tubeC seal each tube with a rubber bung after 3 hours, observe the colour of the indicator high CO2 = yellow atmospheric CO2 = orange low CO2 = purple
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2.39 practical: demonstrating the production of heat from respiring seeds
flask A with the dead seeds flask B with the germinating seeds make sure the cotton wool is plugging the top of each flask hold the thermometer in place with the cotton wool invert the flask record the initial temperature after 4 days, record the final temperature
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2.39 practical: analysis
the thermometer in the flask with the germinating seeds (Flask B) should show an increase in temperature - the seeds in flask B are respiring and producing heat energy in the process flask A should remain at room temperature the seeds in flask A are not respiring because they are dead, so the temperature remains the same this shows that respiration is an exothermic reaction
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2.39 practical: CORMS evaluation evolution of carbon dioxide
change - we will change the content of the boiling tube (germinating seeds, dead seeds or glass beads) organisms - the seeds used should all be of the same age, size and species repeat - we will repeat the investigation several times to ensure our results are reliable measurement 1 - we will observe the change in the hydrogen carbonate indicator measurement 2 - ...after 3 hours same - we will control the volume of hydrogen carbonate indicator, the number of seeds/beads, the temperature of the environment
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2.39 practical: CORMS evaluation evolution of heat
change - we will change the content of the flasks (germinating seeds or dead seeds) organisms - the seeds used should all be of the same age, size and species repeat - repeat the investigation several times to ensure our results are reliable measurement 1 - change in the temperature on the thermometer measurement 2 - ...after 4 days same - control the number of seeds, the starting temperature of the flasks, the material and size of the flasks
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2.40B what is diffusion
diffusion is the movement of molecules from an area of higher concentration to an area of lower concentration
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2.40B what happens in diffusion
molecules move down a concentration gradient as a result of their random movement
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2.40B what does diffusion do in regards to gas exchange
diffusion drives the process of gas exchange
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2.40B what organisms can exchange gases by simple diffusion through the cell membrane
single-celled organisms such as amoeba
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2.40B what can single-celled organisms (amoeba) do through the cell membrane
they can exchange gases sufficiently by simple diffusion through the cell membrane
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2.40B what organisms have exchange surfaces and organ systems that maximise the exchange of materials
multicellular organisms
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2.40B what do multicellular organisms have that maximise the exchange of materials
exchange surfaces and organ systems
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2.40B name examples of gas exchange organs in organisms
gills in fish, lungs in humans & leaves / roots in plants
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2.40B how do gas exchange organs increase the efficiency of exchange
they have a large surface area to increase the rate of transport they have a short diffusion distance for substances to move across (animals have gas exchange surfaces that are well-ventilated to maintain steep concentration gradients)
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2.41B what do the processes of respiration and photosynthesis both rely on
the exchange of oxygen and carbon dioxide
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2.41B what do all living cells do in gas exchange during respiration
all living cells respire
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2.41B what does the process of gas exchange during respiration require
the uptake of oxygen and the release of carbon dioxide
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2.41B how does oxygen diffuse in gas exchange during respiration
oxygen diffuses down the concentration gradient from a high concentration (outside the leaf) to a low concentration (inside the leaf)
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2.41B what do the cells use in respiration so the concentration is low
the cells use oxygen in respiration so the concentration is always low inside the respiring cells
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2.41B how does carbon dioxide diffuse in gas exchange during respiration
the carbon dioxide diffuses down the concentration gradient from a high concentration (inside the leaf) to a low concentration (outside the leaf)
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2.41B when do plant cells photosynthesise during gas exchange during photosynthesis
when there is enough sunlight
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2.41B what does the process of gas exchange during photosynthesis require
it requires the uptake of carbon dioxide and the release of oxygen
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2.41B how does carbon dioxide diffuse in gas exchange during photosynthesis
carbon dioxide diffuses down the concentration gradient from an area of high concentration (outside the leaf) to an area of low concentration (inside the leaf)
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2.41B what do the cells use in photosynthesis so the concentration is low
the cells use carbon dioxide in photosynthesis so the concentration is always low inside the photosynthesizing cells
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2.41B how does oxygen diffuse in gas exchange during photosynthesis
oxygen diffuses down the concentration gradient from a high concentration (inside the leaf) to a low concentration (outside the leaf)
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2.41B in photosynthesis where do carbon dioxide and oxygen diffuse
carbon dioxide diffuses into the leaf oxygen diffuses out of the leaf
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2.41B in photosynthesis what diffuses into the leaf and out of the leaf
carbon dioxide diffuses into the leaf oxygen diffuses out of the leaf
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2.42B the structure of a leaf is adapted for what
both photosynthesis and gas exchange
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2.42B name some things found inside a leaf
cuticle upper epidermis (bricks) palisade mesophyll (longer rectangles) xylem & phloem spongy mesophyll (air bubbles) lower epidermis (smaller bricks w/ hole) guard cell (hole in lower epidermis) cuticle
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2.41B in respiration what diffuses out of the leaf and what diffuses in
carbon dioxide diffuses out of the leaf and oxygen diffuses into the leaf
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2.41B in respiration where do carbon dioxide and oxygen diffuse
carbon dioxide diffuses out of the leaf and oxygen diffuses into the leaf
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2.41B how does gas exchange occur in a single-celled organism
in a single celled organism (like an amoeba) gas exchange occurs through diffusion
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2.42B what is the leaf specifically adapted to do
to maximise gas exchange
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2.42B what are the 3 key gases to consider in gas exchange in a leaf
carbon dioxide - released in respiration but used in photosynthesis oxygen - released in photosynthesis but used in respiration water vapour - released in respiration and transpiration
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2.42B where will gases always diffuse in a leaf
they will always diffuse down a concentration gradient (where there is a high concentration to where there is a low concentration)
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2.42B what is the pathway of carbon dioxide from the atmosphere to chloroplasts by diffusion
atmosphere -> through the open stoma -> air spaces around spongy mesophyll -> diffuses through cell wall & membrane of mesophyll cells -> dissolves in cytoplasm -> diffuses into chloroplast
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2.42B what are some adaptations of the whole leaf for gas exchange
thin which gives a short diffusion distance flat which provides a large surface area to volume ratio they have many stomata which allow movement of gases in and out of the air spaces by diffusion
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2.42B what are some adaptations of the internal leaf structures / tissues for gas exchange
air spaces to allow gas movement around the loosely packed mesophyll cells many stomata in the lower epidermis open in sunlight to allow gas movement in and out of the leaf thin cell walls allow gases to move into the cells easily moist air which gases can dissolve into for easier movement into and out of cells close contact between the cells and the air spaces allows efficient gas exchange for photosynthesis and respiration
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2.43B where are the stomata
they are found between two guard cells predominantly on the lower epidermis of the leaf
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2.43B what are the guard cells responsible for
for the opening and closing of the stomatal pore which controls gas exchange and water loss
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2.43B what does the stomatal pore do
it controls the gas exchange and water loss
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2.43B how does water move in regards to the stomata
the stomata opens when water moves by osmosis into the guard cells
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2.43B when water moves into the guard cells this makes them
turgid
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2.43B when guard cells are turgid this allows
gases to diffuse in and out of the leaf through the stomatal pore
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2.43B when do stomata tend to open
stomata tend to open when there is plenty of water and sunlight
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2.43B when do the stomata close
they close when the guard cells lose water by osmosis
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2.43B where does the water move to when the stomata close
it moves to the neighbouring epidermal cells and they become flaccid
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2.43B what do the epidermal cells become when water enters them
flaccid
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2.43B what does flaccid prevent
it prevents any diffusion in or out of leaf
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2.43B when do stomata tend to close
they tend to close due to low water availability or low sunlight
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2.43B what do the guard cells do
the guard cells control the opening and closing of the stomata
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2.44B when do plants photosynthesise
they photosynthesise when they have access to light however cells respire all the time
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2.44B what does this mean for gas exchange during a 24 hour period
gas exchange in plants varies throughout a 24 hour period
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2.44B what happens during the daytime with plants
during the daytime they both respire and photosynthesise
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2.44B in the day which rate is higher photosynthesis or respiration
photosynthesis tend to be higher - unless there is a low light intensity
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2.44B in the daytime what does this mean for carbon dioxide and oxygen in the plant
there is a net diffusion of carbon dioxide into the plant and a net diffusion of oxygen out of the plant during the day
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2.44B during the night time what do plants do
they only respire
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2.44B in the nighttime what does this mean for carbon dioxide and oxygen in the plant
this means that there is a net movement of oxygen into the plant and a net diffusion of carbon dioxide out of the plant during the nighttime
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2.44B what happens at low light intensities
the rate of photosynthesis is equal to the rate of respiration
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2.44B at low light intensities what does this mean for carbon dioxide and oxygen
this means that there is no net movement of oxygen or carbon dioxide in either direction
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2.44B what do plants do in the day and night
plants photosynthesise and respire during the day but only respire at night time
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2.45B practical: what apparatus do you need for the effect of light on gas exchange in plants
Boiling tubes Cotton wool Aluminium foil Gauze Rubber bungs Hydrogencarbonate indicator Leaves
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2.45B practical: method for the effect of light on gas exchange in plants
measure out 20cm3 of hydrogencarbonate indicator into 4 boiling tubes place cotton wool in the tubes label the boiling tubes A-D tube a - no leaf (control tube) tube b - place a leaf in tube and leave in the light tube c - place a leaf in the tube and wrap it in aluminium foil to block out the light tube d - place a leaf in then tube and wrap it in gauze place a bung on the top of each tube leave all 4 tubes in the light for 30 mins
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2.45B practical: what can hydrogencarbonate indicator be used for
it can be used to study gas exchange in different light conditions
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2.45B practical: results for the effect of light on gas exchange in plants
after 30 mins tube a - control tube should remain an orange / red colour as it is at atmospheric levels no net movement tube b - the leaf is photosynthesising and respiring because the rate of photosynthesis is greater than the rate of respiration the indicator will turn purple as there is less carbon dioxide than atmospheric levels tube c - no sunlight reached the leaf no light - leaf not photosynthesise but will respire producing carbon dioxide indicator turns yellow as carbon dioxide levels increase above atmospheric levels tube d - gauze allowed partial light rate of photosynthesis equals the rate of respiration so there was no net change in carbon dioxide levels indicator remains orange / red
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2.45B practical: what does hydrogencarbonate indicator change
it will change from orange / red to yellow with increasing carbon dioxide or purple with decreasing carbon dioxide
275
2.45B practical: CORMS practical
- change - we will change the availability of light for each boiling tube (not wrapped, wrapped in foil, wrapped in gauze) - organisms - The leaves should be from the same species/age of the plant, they should be approximately the same size - repeat - We will repeat the investigation several times to ensure our results are reliable - measurement 1 - we will observe the change in the hydrogen carbonate indicator - measurement 2 - after 30 minutes - same - control the volume of hydrogen carbonate indicator, the number of leaves, the temperature of the environment
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2.46 what is the thorax
the human chest cavity
278
2.46 what does the thorax consist of
the ribs, intercostal muscles, diaphragm, trachea, bronchi, bronchioles, alveoli and pleural membranes
279
2.46 in the thorax describe the structure of the ribs
bone structure that protects internal organs such as the lungs
280
2.46 in the thorax describe the structure of the intercostal muscles
muscles between the ribs which control their movement causing inhalation & exhalation
281
2.46 in the thorax describe the structure of the diaphragm
sheet of connective tissue and muscle at the bottom of the thorax that helps change the volume of the thorax to allow inhalation & exhalation
282
2.46 in the thorax describe the structure of the trachea
windpipe that connects the mouth and nose to the lungs
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2.46 in the thorax describe the structure of the larynx
also known as the voice box, when air passes across here we are able to make sounds
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2.46 in the thorax describe the structure of the bronchi (plural)
large tubes branching off the trachea with one bronchus (singular) for each lung
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2.46 in the thorax describe the structure of the bronchioles
bronchi split to form smaller tubes called bronchioles in the lungs connected to alveoli
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2.46 in the thorax describe the structure of the alveoli
tiny air sacs where gas exchange take place
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2.46 in the thorax describe the structure of the pleural cavity
the fluid filled space between the pleural membranes which reduces friction and allows the lungs to move freely
288
2.46 the lungs are the ... surface in humans
gas exchange
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2.46 what features do all gas exchange surfaces have in common
large surface area for faster diffusion of gases across the surface thin walls to ensure diffusion distances remain short good ventilation with air so diffusion gradients can be maintained good blood supply to maintain a high concentration gradient so diffusion occurs faster
290
2.47 muscles are only able to pull on bones not push them meaning
there must be two sets of intercostal muscles to work antagonistically to facilitate breathing
291
2.47 what do the external intercostal muscles do
pull the ribcage up
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2.47 what do the internal intercostal muscles do
pull the ribcage down
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2.47 which intercostal muscles pull the ribcage up
the external intercostal muscles
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2.47 which intercostal muscles pull the ribcage down
the internal intercostal muscles
295
2.47 what is the diaphragm
a thin sheet of muscle that separates the chest cavity from the abdomen
296
2.47 during inhalation describe the diaphragm & intercostal muscles
external intercostal muscles contract ribcage moves up and out diaphragm contracts & flattens volume of thorax increases pressure inside thorax decreases - relative to the outside body - air is drawn in
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2.47 during exhalation describe the diaphragm & intercostal muscles
external intercostal muscles relax ribcage moves down and in diaphragm relaxes & becomes dome-shaped volume of thorax decreases pressure inside thorax increases - relative to the outside body - air is forced out
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2.48 how are alveoli highly adapted for gas exchange
large surface area to volume ratio: there are many rounded alveolar sacs minimise / short diffusion distance: alveoli have thin, single layers of cells steep concentration gradient: ventilation maintains high levels of oxygen & low levels of carbon dioxide good bloody supply & maintains concentration gradients: ensures a constant supply of blood high in carbon dioxide & low in oxygen a layer of moisture on the surface of the alveoli helps diffusion as gases dissolve
299
2.49 smoking cigarettes has been linked to
disease in the lungs and is a risk factor in coronary heart disease
300
2.49 what does nicotine in cigarettes do
narrows blood vessels and increases heart rate, leading to increased blood pressure causes high blood pressure that leads to blood clots forming in the arteries potentially resulting in heart attack or stroke
301
2.49 what does carbon monoxide in cigarettes do
binds irreversibly to haemoglobin reducing the capacity of blood to carry oxygen breathing frequency & depth need to increase putting more strain on the breathing system circulatory system needs to pump blood faster - raising blood pressure & increasing risk of coronary heart disease & stroke
302
2.49 what does tar in cigarettes do
it's a carcinogen linked to increased chances of cancerous cells developing in the lungs contributes to COPD which occurs when chronic bronchitis and emphysema occur together
303
2.49 what happens in chronic bronchitis
tar stimulates goblet cells & mucus glands to enlarge and produce more mucus mucus builds up blocking the smallest bronchioles leading to infections build up of mucus can result in damage to the cilia preventing them from beating & removing the mucus a smokers cough is the attempt to move the mucus
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2.49 what happens in emphysema
phagocytes that enter the lungs release elastase an enzyme that breaks down the elastic fibres in the alveoli alveoli become less elastic & cannot stretch so many burst the breakdown of alveoli reduces the surface area for gas exchange patients become breathless & wheezy
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2.49 smoking can cause ... and several types of cancer including ...
coronary heart disease and lung cancer
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2.49 what does nicotine do
it narrows blood vessels - increased blood pressure increased heart rate
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2.49 what does carbon monoxide do
binds irreversibly to haemoglobin breathing frequency has to increase increases risk of coronary heart disease & strokes
308
2.49 emphysema does what
makes the alveoli less elastic & cannot stretch the breakdown of alveoli reduces the surface area for gas exchange
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2.49 smoking increases the risk of cancer which is
the rapid uncontrolled cell growth
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2.49 tobacco smoke contains ______ ________ which permanently binds to the haemoglobin forming __________________ reducing the amount of oxygen being transported by the blood
carbon monoxide carboxyhaemoglobin
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2.49 in healthy lungs the linings of the trachea and bronchi are
specialised to prevent dirt and bacteria entering the lungs
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2.49 the cilia of the lining cells move transporting the mucus
up the airways where it is then swallowed
313
2.49 chemicals in tobacco smoke destroy _____ reducing their number, at the same time mucus production will increase. the mucus cannot be moved out of the airways quickly so it ______ __ causing _______ _____ and increases the risk of infection
cilia builds up smokers cough
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2.49 __________ is a disease resulting from the build up of in refuted mucus in the bronchi and bronchioles
bronchitis
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2.49 smoke can also reach the alveoli damaging them: the alveoli walls break down in places and fuse together forming larger irregular air spaces this ___ the surface area for gas exchange so ____ oxygen diffuses into the blood, this disease is called _________ and kills around 20k people in Britain per year
decreases less emphysema
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2.49 chemicals in cigarettes include:
tar - a carcinogen (a substance that causes cancer) nicotine - an addictive substance which also narrows blood vessels carbon monoxide - reduces the oxygen-carrying capacity of the blood
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2.50 practical: the effect of excerise on breathing method
work out student A's breathing rate at rest count their number breaths for 15 seconds and multiply by 4 repeat to calculate an average student A should then exercise for a set time (at least 4 minutes) count the breaths taken in 15 seconds and multiply by 4 to obtain the breathing rate per minute compare the result to the breathing rate at rest in order to work out the change in breathing rate as a result of exercise repeat this last step every minute after exercise for 5 minutes repeat the process for student B finally, repeat the whole investigation for each student after a period of rest
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2.50 practical: the effect of exercise on breathing results
frequency of breathing increases when exercising this is because muscles are working harder and aerobically respiring more and they need more oxygen to be delivered to them (and carbon dioxide removed) to keep up with the energy demand if they cannot meet the energy demand they will also respire anaerobically, producing lactic acid
319
2.50 practical: the effect of exercise on breathing analysis
after exercise has finished, the breathing rate remained elevated for a period of time this is because the lactic acid that has built up in muscles needs to be removed as it lowers the pH of cells and can denature enzymes catalysing cell reactions it can only be removed by combining it with oxygen - this is known as ‘repaying the oxygen debt’ this can be tested by seeing how long it takes after exercise for the breathing rate to return to normal the longer it takes, the more lactic acid produced during exercise and the greater the oxygen debt that needs to be repaid
320
2.50 practical: what might an unfit individual have
higher breathing rate while resting more rapid increase in breathing rate during exercise longer recovery period for their breathing rate to return back to a normal resting rate
321
2.50 practical: how do you control all variables
ensure students are similar size, general fitness, age, gender and provide each with the same meal before exercise
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2.50 practical: CORMS evaluation
change - We will change whether the student has exercised or not organisms - The students should be of the same age, gender, size and general fitness repeat - We will repeat the investigation several times to ensure our results are reliable measurement 1 - We will measure the change in breathing rate measurement 2 - ...immediately after exercise and each minute for the subsequent 5 minutes same - We will control the type of exercise carried out, the temperature of the environment, the food intake of the students prior to the investigation
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2.50 practical: exercise causes the frequency
exercise causes the frequency of breathing to increase in order to provide more oxygen for respiration and to pay off any subsequent oxygen debt
324
2.50 practical: apparatus needed for the effect of exercise
a stop watch 2 students
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2.56B the loss of water vapour from the leaves is called
transpiration
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2.56B examiners definition of transpiration
the evaporation of water from the surface of a plant
327
2.57B how does temperature affect the rate of transpiration
water will evaporate quickly as the water molecules have more kinetic energy
328
2.57B how does humidity affect the rate of transpiration
humid air - water vapour = smaller conc gradient so transpiration slows down
329
2.57B how does wind speed affect the rate of transpiration
moving air - water vapour blown away from leaf - speeds up transpiration
330
2.57B transpiration .. as wind speed ..
transpiration increases as wind speed increases
331
2.57B transpiration .. as humidity ..
transpiration increases as humidity decreases
332
2.57B transpiration .. as temperature ..
transpiration increase as temp increases
333
2.57B light intensity does NOT affect
evaporation
334
2.57B how does light intensity affect the rate of transpiration
in daylight stomata leaves are open to supply CO2 for photosynthesis allows more water to diffuse out leaves into atmosphere
335
2.58B practical: how to set up a potometer
set up underwater cut the stem shoot stem in bung grease joint w jelly (no air entry/water loss) bung in potometer tap closed full of water lift potometer out of water leave end of capillary tube out of water until air bubble forms & then put in beaker of water measure rate as distance bubble travelled in 5 mins
336
2.58B practical: a potometer is to measure
measure the rate of water uptake from a leafy shoot
337
2.58B practical: we can use potometer to collect readings in normal air or windy conditions by
using a hairdryer on cold
338
2.58B practical: we can use potometer to collect readings in temperature
increases and decreases
339
2.58B practical: we can use potometer to collect readings in increased humidity by
using a clear plastic bag
340
2.58B practical: we can use potometer to collect readings by changing the l & d
lightness and darkness
341
2.58B practical: changing the environmental factors stimulates
all the different conditions which affect the rate of transpiration
342
2.67 what are the factors that may increase the risk of developing coronary heart disease?
1. obesity 2. high blood pressure 3. high cholestrol 4. smoking
343
2.67 how can obesity increase risk of developing coronary heart disease?
carrying extra weight puts a strain on the heart. increased weight can lead to type 2 diabetes which further damages the blood vessels.
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2.67 how can high blood pressure increase risk of developing coronary heart disease?
high blood pressure increases the force of the blood against the artery walls and consequently leads to damage of the vessels.
345
2.67 how can high cholestrol increase risk of developing coronary heart disease?
high cholestrol speeds up the build up of fatty plaques in the arteries which leads to blockages.
346
2.67 how can smoking increase risk of developing coronary heart disease?
chemicals in smoke cause an increase in plaque build up and and increase in blood pressure. carbon monoxide also reduces the oxygen carrying capacity of the red blood cells.
347
2.68 how many types of blood vessel are there? and name them
arteries, veins, capillaries. each vessel is specifically adapted to carry out its particular function efficiently.
348
2.68 what are the smaller vessels that branch off from the arteries called?
arterioles (small arteries)
349
2.68 what are the smaller vessels that branch into veins called ?
venules (small veins)
350
2.68 what are the key features of arteries?
carry blood at high pressure away from the heart carry oxygenated blood (except pulmonary artery) have thick muscular walls containing elastic fibres have a narrow lumen blood flows through at a fast speed.
351
2.68 how is the structure of an artery adapted to its function?
thick muscular walls containing elastic fibres withstand the high pressure of blood and maintain the blood pressure as it recoils after the blood has passed through a narrow lumen also helps to maintain high pressure.
352
2.68 what are the key features of veins?
carry blood at low pressure towards the heart carry deoxygenated blood (other than the pulmonary vein) have thin walls have a large lumen contain valves blood flows through a slow speed
353
2.68 how is the structure of a vein adapted to its function?
a large lumen reduces resistance to blood flow under low pressure. valves prevent the backflow of blood as it is under low pressure
354
2.68 what are the key features of capillaries?
carry blood at low pressure within tissues carry both oxygenated and deoxygenated blood have walls that are one cell thick have 'leaky' walls speed of blood flow is slow
355
2.68 how is the structure of a capillary adapted to its function?
capillaries have walls that are one cell thick (short diffusion distance) so substances can easily diffuse in and out of them. The 'leaky' walls allow blood plasma to leak out and form tissue fluid surrounding cells.
356
2.51 organisms must exchange what substances to function properly
food molecules and waste
357
2.51 the exchange of food molecules and waste in organisms happens via
diffusion, osmosis and active transport across the cell membrane
358
2.51 give an example of a unicellular organism
amoebas
359
2.51 unicellular organisms like amoebas have what
large surface areas relative to their volume meaning the distance from the surface to the centre is small
360
2.51 unicellular organisms like amoebas do not need
specialised exchange surfaces / transport systems
361
2.51 what are the specialised exchange surfaces / transport systems that unicellular organisms do not need
transport systems such as diffusion, osmosis and active transport through the cell membrane
362
2.51 in an amoeba what does the oxygen do
oxygen diffuses in for respiration
363
2.51 in an amoeba what does the waste products - including CO2
waste products - including CO2 - diffuses out
364
2.51 in an amoeba what does the water do
water moves in / out by osmosis
365
2.51 what do unicellular organisms not require
unicellular organisms such as amoeba do not require transport systems due to their large surface area to volume ratio
366
2.52 an example of a multicellular organism
humans - they are composed of many cells
367
2.52 why are humans multicellular organisms
bodies are composed of many cells
368
2.52 what do multicellular organisms have
they have multiple cell layers
369
2.52 what do the multiple cell layers in organisms mean for the distance
the distance from the surface to the centre too long for diffusion alone
370
2.52 larger multicellular organisms require what
transport systems
371
2.52 why do larger organisms require transport systems
diffusion to all cells would be too slow to meet the organisms needs
372
2.52 in animals what carries essential substances in the blood
circulatory system
373
2.52 what is the transport system in animals
the circulatory system
374
2.52 in plants what transports substances
vascular system
375
2.52 what is the transport system in plants
vascular system
376
2.52 what substances does the vascular system transport in plants
the xylem moves water and minerals from roots to shoots the phloem distributes sugars and amino acids throughout the plant
377
2.52 what does the xylem do regarding transport systems in multicellular organisms
water and mineral ions from roots to shoots
378
2.52 what does the phloem do regarding transport systems in multicellular organisms
sugars and amino acids from source to sink
379
2.52 what does the circulatory system do regarding transport systems in multicellular organisms
blood carries oxygen, glucose, carbon dioxide, water & waste around the body
380
2.52 what do multicellular systems have
transport systems
381
2.53 what is the role of the phloem
it transports sucrose and amino acids from where they are produced / stored to where they are needed
382
2.53 where are sucrose and amino acids produced
in the leaves while plants photosynthesise so they are transported from the leaves to the other parts of the plant
383
2.53 what is the phloem formed by
it is formed from living cells forming a tube with small holes through which substances can move
384
2.53 & 2.54 what do the xylem and phloem make up
the transport system of vascular plants
385
2.53 & 2.54 what makes up the transport system of vascular plants
the xylem and phloem
386
2.54 what is the role of the xylem
to transport water and mineral ions from the roots to other parts of the plant
387
2.54 what is the xylem formed from
formed from a hollow tube of dead cells reinforced by lignin which provides a route for the column of water to move through the plant by transpiration
388
2.54 what cell content does the xylem have
no cell contents just a continuous column of water
389
2.54 what happens to the original cell wall in the xylem
original cell wall between cells has broken down
390
2.54 what happens to the walls in the xylem
the walls are thickened with lignin
391
2.54 what are the walls thickened with in the xylem
lignin
392
2.54 what does the structure of the xylem allow
it allows it to function as a vessel for the transport of water through the plant
393
2.55B what are root hairs
single-celled extensions of epidermis cells in the root
394
2.55B where do root hairs grow
they grow between soil particles and absorb water and minerals from the soil
395
2.55B how are root hair cells adapted for the efficient uptake of water - by osmosis - ad mineral ions - by active transport
they contain mitochondria which release energy for active transport root hairs increase the surface are of plant roots increasing the rate at which water and minerals can be taken up
396
2.55B what are root hair cells adapted for
the efficient uptake of water by osmosis & mineral ions by active transport
397
2.55B what does mitochondria do in root hair cells
they release energy for active transport
398
2.55B what do root hairs do in regard to the surface area
they increase the surface area of plant roots, increasing the rate at which water and minerals can be taken up
399
2.55B what do root hair cells take up
mineral ions and water from the soil
400
2.55B which is taken up by active transport with root hair cells
mineral ions from the soil
401
2.55B which is taken up by osmosis with root hair cells
water
402
2.55B root hair cells take up mineral ions from the soil by
active transport
403
2.55B water moves into the root hair cell by
osmosis
404
2.55B the water concentration of the cell cytoplasm is
reduced due to the presence of mineral ions
405
2.55B why is the water concentration of the cell cytoplasm is reduced
due to the presence of mineral ions
406
2.55B what does the structure of a root specifically allow it to do
it allows it to maximise absorption of water by osmosis and mineral ions by active transport
407
2.55B how does water move in the root hair cells
by osmosis into the root hair cells
408
2.55B what does water move through in the root hair cells
the root cortex and into the xylem vessels
409
2.55B when the water gets into the xylem what does it do
it is carried up the leaves where it enters mesophyll cells
410
2.55B what is the pathway for the root of water through the root hair cell
root hair cell -> root cortex cells -> xylem -> leaf mesophyll cells
411
2.59 what does the blood consist of
red blood cells, white blood cells, platelets & plasma
412
2.59 how much of the blood is made up of plasma
over half
413
2.59 statistics - percentage of what is in blood
55% plasma 45% red blood cells <1% white blood cells & platelets
414
2.59 structure of red blood cells
biconcave discs containing no nucleus to maximise the available capacity to carry the protein haemoglobin
415
2.59 structure of white blood cells
large cells containing a large nucleus - different types have slightly different structures and functions
416
2.59 structure of platelets
fragments of cells
417
2.59 structure of plasma
clear, straw -coloured aqueous solution
418
2.60 what is plasma
a straw-coloured liquid which the other components of blood are suspended with
419
2.60 what does plasma transport
carbon dioxide digested food and mineral ions urea hormones heat energy
420
2.60 what is plasma important for
the transport of many substances
421
2.60 plasma transports carbon dioxide explain more
carbon dioxide - waste product of respiration dissolved in plasma & transported from respiring cells to the lungs
422
2.60 plasma transports digested food & mineral ions explain more
dissolved particles absorbed from the small intestine and delivered to requiring cells around the body
423
2.60 plasma transports urea explain more
urea is a waste substance dissolved in the plasma and transported to the kidneys
424
2.60 plasma transports hormones explain more
chemical messengers released into the blood from the endocrine organs (glands) and delivered to target tissues/organs of the body
425
2.59 plasma transports heat energy explain more
heat energy (created in respiration) is transferred to cooler parts of the body or to the skin where heat can be lost
426
2.60 plasma transports what substances & explain them
carbon dioxide - the waste product of respiration, dissolved in the plasma and transported from respiring cells to the lungs digested food and mineral ions - dissolved particles absorbed from the small intestine and delivered to requiring cells around the body urea - urea is a waste substance dissolved in the plasma and transported to the kidneys hormones - chemical messengers released into the blood from the endocrine organs (glands) and delivered to target tissues/organs of the body heat energy - heat energy (created in respiration) is transferred to cooler parts of the body or to the skin where heat can be lost
427
2.61 what are red blood cells
they are specialised cells which carry oxygen to respiring cells
428
2.61 how are red blood cells adapted to carry oxygen to respiring cells
- they are full of haemoglobin - they have no nucleus which allows more space for haemoglobin to be packed in - shaped as a biconcave disc which gives them a large surface area to volume ratio to maximise diffusion of oxygen in and out
429
2.62 what are white blood cells a part of
the body's immune system
430
2.62 what are white blood cells
they are specialised cells that defend against pathogenic microorganisms
431
2.62 what are the two main types of white blood cell
phagocytes and lymphocytes
432
2.62 what do phagocytes carry out
phagocytosis by ingesting pathogens
433
2.62 how do phagocytes carry out phagocytosis
by ingesting pathogens
434
2.62 phagocytes have what type of cell surface
a sensitive cell surface membrane that can detect chemicals produced by pathogenic cells
435
2.62 phagocytes have a sensitive cell surface membrane which
can detect chemicals produced by pathogenic cells
436
2.62 when phagocytes encounter the pathogenic cell what do they do
they will engulf it and release digestive enzymes to digest it
437
2.62 what type of response is phagocytosis
a non-specific immune response
438
2.62 process of phagocytosis
bacterial pathogen is engulfed by the phagocyte (phagocytosis) digestive enzymes are released to destroy the bacteria
439
2.62 what do lymphocytes do
they produce antibodies
440
2.62 what are antibodies
they are proteins with a shape that is specific / complementary to the antigens on the surface of the pathogen
441
2.62 what do lymphocytes provide
a specific immune response
442
2.62 why do lymphocytes provide a specific immune response
as the antibodies produced will only fit one type of antigen on a pathogen
443
2.62 what do lymphocytes do
they produce antibodies that are specific to the antigen on the pathogen
444
2.62 what is the main component of the immune system
white blood cells
445
2.62 what is the role of the immune system
when a pathogen enters the body, the immune system should prevent the infectious organism from reproducing and to destroy it
446
2.62 when does an organism have immunity
when they have sufficient levels of antibodies to protect it from a particular disease
447
2.62 what are the stages of infection
the pathogen enters the blood stream and multiplies it releases toxins & infects body cells causing symptoms in the patient phagocytes recognise the invading pathogen and engulf & digest it (non-specific response) the pathogen encounters a lymphocyte which recognises its antigens the lymphocyte produces specific antibodies to fight it the lymphocyte also clones itself to produce lots of lymphocytes - producing the specific antibody required antibodies destroy pathogens phagocytes engulf and digest destroyed pathogens
448
2.62 stage 1 of the response to infection
the pathogen enters the blood stream and multiplies
449
2.62 stage 2 of the response to infection
a release of toxins (in the case of bacteria) and infection of body cells causes symptoms in the patient
450
2.62 stage 3 of the response to infection
phagocytes that encounter the pathogen recognise that it is an invading pathogen and engulf and digest (non-specific response)
451
2.62 stage 4 of the response to infection
the pathogen encounters a lymphocyte which recognises its antigens
452
2.62 stage 5 of the response to infection
the lymphocyte starts to produce specific antibodies to combat that particular pathogen
453
2.62 stage 6 of the response to infection
the lymphocyte also clones itself to produce lots of lymphocytes (all producing the specific antibody required)
454
2.62 stage 7 of the response to infection
antibodies destroy pathogens
455
2.62 stage 8 of the response to infection
phagocytes engulf and digest the destroyed pathogens
456
2.62 what is an antigen
is a molecule found on the surface of a cell
457
2.62 what is an antibody
a protein made by lymphocytes that is complementary to an antigen and, when attached, clumps them together and signals the cells they are on for destruction
458
2.63B what are vaccines used for
to induce immunity to infectious diseases
459
2.63B what have vaccines done
they have reduced the cases of certain diseases or even eradicated them
460
2.63B diseases vaccines have eradicated / reduced the case of
smallpox, measles, mumps and tetanus
461
2.63B what does a vaccine contain
harmless versions of a pathogen
462
2.63B what are the different methods scientists use to ensure the vaccines contain harmless pathogens
killing the pathogen (attenuated vaccine) which means making it unable to grow or divide using fragments of pathogens rather than whole cells
463
2.63B how may a vaccine be administered
orally, nasally or via an injection
464
2.63B how do vaccines work
when in the bloodstream the antigens in the vaccine trigger an immune response: lymphocytes recognise the antigens in the bloodstream the activated lymphocytes produce antibodies specific to the antigen encountered memory cells are produced from the lymphocytes memory cells and antibodies subsequently remain circulating in the blood stream
465
2.63B what is the immune response vaccines trigger
lymphocytes recognise the antigens in the bloodstream the activated lymphocytes produce antibodies specific to the antigen encountered memory cells are produced from the lymphocytes memory cells and antibodies subsequently remain circulating in the blood stream
466
2.63B how does long-term immunity work by vaccination
memory cells are produced when reacting & fighting the vaccine, so if the antigen is triggered again the antibodies are produced much faster
467
2.63B future infection from the same pathogen to someone who was vaccinated means
the response will be much faster and much larger compared to the initial response
468
2.63B why is an individual said to be immune after vaccinated
due to the rapid nature of the response, the pathogen is unable to cause disease
469
2.64B what are platelets
they are fragments of cells
470
2.64B what are platelets involved in
they are involved in blood clotting and forming scabs
471
2.64B what happens after the skin is broken involving platelets
platelets arrive to stop the bleeding
472
2.64B what is the series of reactions that occur within the blood plasma after the skin is broken
platelets release chemicals that cause soluble fibrinogen proteins to convert into insoluble fibrin this forms an insoluble mesh across the wound red blood cells become trapped, forming a clot the clot eventually dries and develops into a scab
473
2.64B stage 1 of the series of reactions after the skin has been cut
platelets release chemicals that cause soluble fibrinogen proteins to convert into insoluble fibrin
474
2.64B stage 2 of the series of reactions after the skin has been cut
there is an insoluble mesh formed across the wound
475
2.64B stage 3 of the series of reactions after the skin has been cut
red blood cells become trapped, forming a clot
476
2.64B stage 4 of the series of reactions after the skin has been cut
the clot eventually dries and develops into a scab
477
2.64B how does the reactions that occur after a cut help the individual
it helps to prevent excessive blood loss and protect the wound from bacteria entering until new skin has formed
478
2.65 what is the heart organ in terms of pumps
a double pump
479
2.65 what is pumped into the left side of the heart from the lungs
oxygenated blood
480
2.65 where does oxygenated blood from the lungs enter the heart
on the left side
481
2.65 what is done with the oxygenated blood from the lungs when it is pumped into the left side of the heart
it is pumped to the rest of the body - the systemic circuit -
482
2.65 which ventricle is thicker & why
the left has a thicker muscle wall as it has to pump blood at high pressure around the entire body
483
2.65 which ventricle pumps blood around the whoe body
the left ventricle therefore it has a thicker muscle wall
484
2.65 where does deoxygenated blood from the body enter the heart
on the right side
485
2.65 what is pumped into the right side of the heart from the body
deoxygenated blood
486
2.65 what is done with the deoxygenated blood from the body when it is pumped into the right side of the heart
it is pumped to the lungs - the pulmonary circuit -
487
2.65 which side of the heart uses the pulmonary circuit
the right side with deoxygenated blood
488
2.65 which side of the heart uses the systemic circuit
the left side with the oxygenated blood
489
2.65 what pressure is the right ventricle pumping blood at
a lower pressure to the lungs
490
2.65 what separates the two sides of the heart
the septum - muscle wall
491
2.65 what does the septum - muscle wall - do in the heart
it separates the two sides of the heart
492
2.65 where is blood pumped in veins
towards the heart
493
2.65 where is blood pumped in arteries
away from the heart
494
2.65 where is blood pumped towards the heart
in the veins
495
2.65 what do the coronary arteries do
they supply the cardiac muscle tissue of the heart with oxygenated blood
496
2.65 where is blood pumped away from the heart
in the arteries
497
2.65 as the heart is a muscle what constant supply does it need
it needs a constant supply of oxygen (and glucose) for aerobic respiration to release energy to allow continued muscle contraction
498
2.65 what do valves do
they prevent blood flowing backwards
499
2.65 what prevents blood flowing backwards
valves
500
2.65 why does the heart need a constant supply of oxygen (and glucose) for aerobic respiration to release energy to allow continued muscle contraction
because it is a muscle
501
2.65 describe the flow of oxygenated blood in the heart
on the left side in through the pulmonary vein into the left atrium through the bicuspid valve into the left ventricle through the semi-lunar valves out of the aorta
502
2.65 describe the flow of deoxygenated blood in the heart
on the right side in through the vena cava into the right atrium through the tricuspid valve into the right ventricle through the semi-lunar valves out of the pulmonary artery
503
2.65 how to remember veins go into the heart
veIN into the heart
504
2.65 how to remember arteries go away from the heart
Arteries are Away from the heart
505
2.65 what is the pathway of blood through the heart BOTH DEOXYGENATED & OXYGENATED
DEOXYGENATED blood coming from the body flows through the vena cava and into the right atrium the atrium contracts and the blood is forced through the tricuspid valve into the right ventricle the ventricle contracts and the blood is pushed through the semilunar valve into the pulmonary artery the blood travels to the lungs and moves through the capillaries past the alveoli where gas exchange takes place low pressure blood flow on this side of the heart prevents damage to the capillaries in the lungs OXYGENATED blood returns via the pulmonary vein to the left atrium the atrium contracts and forces the blood through the bicuspid valve into the left ventricle the ventricle contracts and the blood is forced through the semilunar valve and out through the aorta thicker muscle walls of the left ventricle produce a high enough pressure for the blood to travel around the whole body
506
2.65 what is the pathway of blood through the heart - just DEOXYGENATED
DEOXYGENATED blood coming from the body flows through the vena cava and into the right atrium the atrium contracts and the blood is forced through the tricuspid valve into the right ventricle the ventricle contracts and the blood is pushed through the semilunar valve into the pulmonary artery the blood travels to the lungs and moves through the capillaries past the alveoli where gas exchange takes place low pressure blood flow on this side of the heart prevents damage to the capillaries in the lungs
507
2.65 what is the pathway of blood through the heart - just OXYGENATED
OXYGENATED blood returns via the pulmonary vein to the left atrium the atrium contracts and forces the blood through the bicuspid valve into the left ventricle the ventricle contracts and the blood is forced through the semilunar valve and out through the aorta thicker muscle walls of the left ventricle produce a high enough pressure for the blood to travel around the whole body
508
2.66 how is the heart rate measured
by counting the number of times the heart beats in a minute - bpm
509
2.66 the natural resting heart rate is controlled by what
a group of cells located in the right atrium called the pacemaker
510
2.66 what is the role of the pacemaker
to coordinate the contraction of the heart muscle & regulate the heart rate
511
2.66 how does the pacemaker function
pacemaker cells send out electrical impulses which initiate a contraction in the cardiac muscle
512
2.66 why does the heart pumps blood to respiring cells
to supply oxygen and glucose and remove respiratory waste
513
2.66 during exercise what do muscle cells do
they respire faster to increase energy supply
514
2.66 when is respiration aerobic & anaerobic
aerobic during moderate exercise and anaerobic during intense exercise
515
2.66 what types of respiration occur during moderate & intense exercise
aerobic during moderate exercise and anaerobic during intense exercise
516
2.66 why do muscles respire faster during exercise
to increase energy supply
517
2.66 what do muscles do during exercise
they respire faster
518
2.66 how do muscle cells increase the energy supply during exercise
they respire faster
519
2.66 what does increased respiration raise the need for
oxygen, glucose and waste removal
520
2.66 how does the nervous system respond to an increased respiration rate
increasing heart rate to deliver oxygen and glucose more frequently & increasing the volume of blood pumped to supply larger amounts of oxygen and glucose
521
2.66 what happens to the heart rate at the end of exercise
it main remain high as oxygen is required in the muscles to break down the lactic acid from anaerobic respiration
522
2.66 why does heart rate remain high after exercise
it main remain high as oxygen is required in the muscles to break down the lactic acid from anaerobic respiration
523
2.66 production of the hormone adrenaline also does what
it also increases heart rate as part of a 'fight or flight' response
524
2.66 as part of the fight or flight response what hormone is released
adrenaline
525
2.66 what hormone increases the heart rate
adrenaline
526
2.67 what are the coronary arteries
the blood vessels which supply cardiac muscle with oxygen glucose
527
2.67 what happens in coronary heart disease
layers of fatty material (plaque) build up inside the coronary arteries
528
2.66 what are the fatty deposits in coronary heart disease made from
the fatty deposits are mainly formed from cholesterol
529
2.66 where are the two main sources of cholesterol in the body
dietary cholesterol - from animal products eaten cholesterol synthesised by the liver
530
2.66 what happens to the artery wall when plaque builds up
it becomes less elastic
531
2.66 what is plaque made from
cholesterol and white blood cells
532
2.66 what happens to the coronary artery when plaque builds up
coronary artery narrows restricting blood flow
533
2.66 what can lead to coronary heart disease
a diet too high in saturated fat and cholesterol
534
2.66 what does a buildup of plaque in the coronary arteries do
it narrows the lumen
535
2.66 what happens if coronary artery becomes partially or completely blocked by these fatty deposits
the flow of blood through the arteries is reduced, resulting in a lack of oxygen for the heart muscle
536
2.66 what does partial blockage do to the coronary arteries
it creates a restricted blood flow to the cardiac muscle cells and results in severe chest pains called angina
537
2.66 what does complete blockage do to the coronary arteries
means cells in that area of the heart will not be able to respire aerobically, leading to a heart attack
538
2.66 what is the effect of a narrowed lumen in a coronary artery
reduced blood flow to the heart
539
2.66 what does carrying extra weight mean for CHD
carrying extra weight puts a strain on the heart increased weight can lead to type 2 diabetes which further damages your blood vessels
540
2.66 what does a high blood pressure mean for CHD
this increases the force of the blood against the artery walls and consequently leads to damage of the vessels
541
2.66 what does high cholesterol mean for CHD
speeds up the build up of fatty plaques in the arteries leading to blockages
542
2.66 what does smoking mean for CHD
chemicals in smoke cause an increase in plaque build up and an increase in blood pressure carbon monoxide also reduces the oxygen carrying capacity of the red blood cells
543
2.68 what are the three main types of blood vessel
arteries, veins or capillaries
544
2.68 what are the smaller vessels that branch of arteries
arterioles (smaller arteries)
545
2.68 what are arterioles
smaller arteries that branch off arteries
546
2.68 what are the smaller vessels that branch of veins
venules (smaller veins)
547
2.68 what are venules
smaller veins that branch off veins
548
2.68 what do each blood vessel do
they have a particular function and are specifically adapted to carry out that function efficiently
549
2.68 what are the key features of arteries?
carry blood at high pressure away from the heart carry oxygenated blood (except pulmonary artery) have thick muscular walls containing elastic fibres have a narrow lumen blood flows through at a fast speed.
550
2.68 how is the structure of an artery adapted to its function?
thick muscular walls containing elastic fibres withstand the high pressure of blood and maintain the blood pressure as it recoils after the blood has passed through a narrow lumen also helps to maintain high pressure
551
2.68 what are the key features of veins?
carry blood at low pressure towards the heart carry deoxygenated blood (other than the pulmonary vein) have thin walls, have a large lumen, contain valves blood flows through a slow speed
552
2.68 how is the structure of a vein adapted to its function?
a large lumen reduces resistance to blood flow under low pressure. valves prevent the backflow of blood as it is under low pressure
553
2.68 what are the key features of capillaries?
carry blood at low pressure within tissues carry both oxygenated and deoxygenated blood have walls that are one cell thick have 'leaky' walls speed of blood flow is slow
554
2.68 how is the structure of a capillary adapted to its function?
capillaries have walls that are one cell thick (short diffusion distance) so substances can easily diffuse in and out of them the 'leaky' walls allow blood plasma to leak out and form tissue fluid surrounding cells
555
2.68 capillaries are the site of what
capillaries within body tissues where exchange of substances take place
556
2.68 why are arterial walls thicker than vein walls
to withstand higher blood pressure
557
2.69 the circulatory system consists of what
a closed network of blood vessels connected to the heart
558
2.69 where oxygenated blood carried
oxygenated blood is carried away from the heart and towards organs in arteries
559
2.69 the steps in network
oxygenated blood is carried away from the heart and towards organs in arteries these narrow to arterioles and then capillaries as they pass through the organ in the organs, respiring cells use up the oxygen from the blood the capillaries widen to venules and finally veins as they move away from the organs veins carry deoxygenated blood back towards the heart
560
2.69 a different network of lymphatic vessels collect what
all the excess tissue fluid that leaks out of the capillaries and delivers it back to the circulatory system
561
2.68 which network collects all the excess tissue fluid that leaks out of the capillaries and delivers it back to the circulatory system
lymphatic vessels
562
2.69 what moves towards the heart
vena cava & pulmonary vein
563
2.69 what moves away the heart
aorta & pulmonary artery
564
2.69 what moves towards the lung
pulmonary artery
565
2.69 what moves away the lung
pulmonary vein
566
2.69 what moves towards the kidney
renal artery
567
2.69 what moves away the kidney
renal vein
568
2.71 what are the excretory products of the lungs
carbon dioxide (via blood plasma)
569
2.71 what are the excretory products of the kidneys
urea
570
2.71 what are the excretory products of the skin
urea
571
2.71 water is lost from the body in the following ways:
via the lungs during exhalation (breathing out) lost from the skin as sweat (along side mineral ions and urea)
572
2.72B what does the kidney do
it filters the blood and removes any excess materials and passes them to the bladder to be excreted
573
2.72B the kidney contains millions of tiny structures called
nephrons
574
2.72B nephrons are structures which
filter the blood
575
2.72B what are the 3 main regions of the kidney
cortex, medulla and renal pelvis
576
2.74B what are the 3 stages that occur in the nephron
ultrafiltration, selective reabsorption and water reabsorption
577
2.74B the main sections in a nephron
bowman's capsule proximal convoluted tubule loop of henle distal convoluted tubule collecting duct
578
2.74B surrounding the tubule is a network of
capillaries with a knotted section which sits inside the bowman's capsule
579
2.74B where does the glomerulus sit
inside the bowmans capsule
580
2.74B what shape is the bowmans capsule
cup shaped
581
2.74B the glomerulus is a knot of
capillaries
582
2.74B where is glucose reabsorbed
in the proximal first convoluted tubule
583
2.74B the gates that facilitate the active transport of glucose are
only found in the proximal convoluted tubule
584
2.74B the cells lining in the PCT have many mitochondria to
provide ATP (energy) for active transport
585
2.74B the cells lining in the PCT have a folded membrane
to increase surface area
586
2.74B where is water reabsorbed
loop of henle and collecting duct
587
2.74B where are salts reabsorbed
loop of henle
588
2.75B step1. the diameter of the efferent arteriole at the exit of the glomerulus is
smaller than the diameter of the afferent arteriole at the entrance causing a build up of pressure
589
2.75B step1. the build up of pressure in the capillaries forms the
glomerulus
590
2.75B step2. the pressure causes the smaller molecules being carried in the blood to be forced out of the capillaries and into
the bowman’s capsule where they form the glomerular filtrate
591
2.75B step2. small molecules like urea, glucose, amino acids, water and salts are forced
out the glomerulus into the bowmans capsule
592
2.75B step3. larger molecules like proteins or red blood cells are
too big to fit across the capillary wall so they stay in the blood
593
2.75B where is water reabsorbed
loop of henle & collecting duct
594
2.75B where are salts reabsorbed
loop of henle
595
2.75B where is glucose reabsorbed
proximal first convoluted
596
2.75B where is urea reabsorbed
it is NOT reabsorbed
597
2.75B what small molecules are pushed through
urea, glucose, amino acids, water and salts
598
2.75B what large molecules are too big to go through so stay in the blood
proteins and red blood cells
599
2.75B what makes up the glomerular filtrate
urea, glucose, amino acids, water and salts
600
2.77B after the glomerular filtrate enters the bowman’s capsule what's the first thing to be reabsorbed
glucose is the first substance to be reabsorbed at the proximal (first) convoluted tubule
601
2.77B selective reabsorption takes place by
active transport
602
2.77B the cells lining in the PCT have a folded membrane for
an increased surface area
603
2.77B the cells lining in the PCT have many mitochondria to
provide ATP (energy) for active transport
604
2.77B reabsorption of glucose cannot take place anywhere else in the nephron as
the gates that facilitate the active transport of glucose are only found in the proximal convoluted tubule
605
2.79B urine contains
water, urea and ions
606
2.79B if someone is diabetic their urine may contain
glucose
607
2.79B urine produced by the kidneys contains a mixture of
urea excess mineral ions excess water
608
2.79B small quantities of urine are usually darker yellow / orange in colour because
it contains little water and so the urea is more concentrated
609
2.79B large quantities of urine are usually pale yellow in colour
because it contains a lot of water and so the urea is less concentrated
610
2.77B where does selective reabsorption of glucose occur
in the proximal convoluted tubule
611
2.79B what produces urine
the kidneys
612
2.77B what's special about the reabsorption of glucose
its selectively reabsorped
613
2.70 within plant cells there are a range of ... reactions taking place producing ... products
metabolic reactions producing waste products
614
2.70 some waste products in plants are used up but others must exit the plant via
the leaf organ
615
2.70 waste products / substances in excess inside the plant are
oxygen, carbon dioxide, water / water vapour, other unwanted chemical substances
616
2.70 oxygen and carbon dioxide are both what in plants
reactants and waste products
617
2.70 what are both reactants and waste products in plants
oxygen and carbon dioxide
618
2.70 what affects the waste products within plants
the intensity of light
619
2.70 during the day when there is sufficient light what happens inside the plant
the rate of photosynthesis is higher than the rate of respiration more oxygen is released than used in respiration less carbon dioxide is released than used in photosynthesis net effect - oxygen is in excess & a waste products
620
2.70 during the night when there is insufficient light what happens inside the plant
there is no photosynthesis, only respiration oxygen is used in respiration and carbon dioxide is produced no photosynthesis means that no carbon dioxide is used net effect - carbon dioxide is in excess and a waste product
621
2.70 what happens to the gas in excess
it diffuses out of the plant via the leaf organ the gases exit through the stomata
622
2.70 where do the gases in excess diffuse out of the plant
through the stomata
623
2.70 as the excretion of gases in plants occurs via diffusion it is technically
not an active process
624
2.70 the majority of water vapour lost from a plant is not
not a waste product of metabolism
625
2.70 what is the majority of water vapour lost from a plant
water that has been drawn up from the roots in the transpiration stream
626
2.70 excretion in plants in the night:
carbon dioxide is excreted at night when the rate of respiration exceeds the rate of photosynthesis water vapour is excreted through transpiration
627
2.70 excretion in plants in the day:
oxygen is excreted in the day when the rate of photosynthesis exceeds the rate of respiration water vapour is excreted through transpiration
628
2.70 plant cells can do what to molecules
break them down
629
2.70 plant cells can break down molecules into
chemical substances no longer required by the plant
630
2.70 some of the substances in the plant cannot
be converted into another useful compound and so must be removed from the plant
631
2.70 some of the substances in the plant must be removed from the plant because
they cannot be converted into another useful compound
632
2.70 chemical waste materials in the plant are stored where
in the dying tissues of a plant
633
2.70 when the dying tissues of a plant filled with chemical waste materials falls off
the substances are removed (in autumn leaves fall as different colors)
634
2.73B two functions of the urinary system are
to filter waste products from the blood and expel it from the body as urine to control the water levels of the body (osmoregulation)
635
2.73B the urinary system consists of
two kidneys joined to the bladder by two tubes called the ureters
636
2.73B in another tube the urethra does what
the carries urine from the bladder to outside the body
637
2.73B each kidney is connected to what
the renal artery which comes from the aorta and delivers oxygenated blood to the kidney the renal vein which delivers the deoxygenated blood from the kidney to the vena cava
638
2.73B what are the structures in the urinary system
kidney ureter bladder urethra
639
2.73B explain the kidney
two beam-shaped organs that filter the blood
640
2.73B explain the ureter
tube connecting the kidney to the bladder
641
2.73B explain the bladder
organ that stores urine as it is produced by the kidney
642
2.79B what is urine
excess water, salts and urea
643
2.73B explain the urethra
tube that connects the bladder to the exterior - where urine is released
644
2.79B what does water contain
water, urea and salts
645
2.76B what is reabsorbed when the filtrate drips through the loop of henle
necessary salts
646
2.76B where are necessary salts reabsorbed
in the loop of henle
647
2.76B how necessary salts reabsorbed
by diffusion and active transport
648
2.76B as salts are reabsorbed in the loop of henle, what follows
water by osmosis
649
2.76B how does water get reabsorbed into the blood
by osmosis
650
2.76B water follows what as it is absorbed back in the blood
water follows salts being reabsorbed
651
2.76B where is water reabsorbed
some in the loop of henle but most in the collecting duct
652
2.76B water is reabsorbed in the collecting duct in different amounts why
depending on how much water the body needs at that time
653
2.76B when ADH is released what happens in relation to water reabsorption
the permeability increases when permeability increases more water is absorbed
654
2.76B where does water reabsorption occur
along the nephron tubules in the kidney
655
2.76B why is water reabsorption important
its important for osmoregulation
656
2.76B the control of water reabsorption by the tubules is an example of
negative feedback (when the feedback causes the corrective measures to be turned off so returns the system to its original / normal level)
657
2.76B water is reabsorbed back into the blood stream by what process
renal tubular reabsorption
658
2.76B where does renal tubular reabsorption take place
in the renal tubules which are small tube-like structures in the kidneys
659
2.76B what are renal tubules
small tube-like structures in the kidneys
660
2.76B what does diuresis mean
flow of urine from the body
661
2.76B what does antidiuresis mean
producing less urine
662
7.76B what happens when the loss of is detected
it is detected by receptor cells in the hypothalamus situated above the pituitary gland the cells are sensitive to the concentration of the blood so the pituitary gland releases more ADH the ADH travels in the blood to the kidneys at the kidney tubules the collecting ducts become more permeable to water so more water is reabsorbed
663
2.76B any change in water level of the blood is detected by what
the hypothalamus
664
2.76B what is negative feedback
change in conditions of the body is detected process is started to return body to normal when body is normal corrective process is switched off
665
2.76B what does the hypothalamus do when it detects a change to the water level
it sends a signal to the pituitary gland in the brain
666
2.76B what does the pituitary gland release
a hormone called ADH
667
2.78B what does the pituitary gland release
a hormone called ADH
668
2.76B how much ADH is released depends on
how much the kidneys need to reabsorb from the filtrate
669
7.68B ADH affects what
the permeability of the tubules to water
670
2.78B what is the role of ADH
it affects the permeability of the kidney tubules / the collecting duct of the kidney nephron more water reabsorbed - less water excreted
671
2.76B if the water content is too high
the pituitary gland in the brain releases less ADH which leads to less water being reabsorbed in the collecting ducts of the kidney by osmosis (the collecting ducts become less permeable to water) as a result, the kidneys produce a large volume of dilute urine
672
2.76B if the water content is too low
the pituitary gland releases more ADH which leads to more water being reabsorbed in the collecting ducts of the kidney by osmosis (the collecting ducts become more permeable to water) as a result, the kidneys produce a small volume of concentrated urine
673
2.80 animals and plants respond to what
changes in their environment
674
2.80 why do animals and plants need to be able to respond to changes
to coordinate the activities of their different organs
675
2.80 what are examples of internal / external environment changes
changes in temperature or pH
676
2.80 in order to function properly and efficiently organisms have
different control and communication systems that ensure their internal conditions are kept relatively constant
677
2.81 physiological control systems maintain what
the internal environment with restricted limits through a process known as homeostasis
678
2.81 what is homeostasis
the maintenance of a constant internal environment
679
2.81 two examples of homeostasis
body water content and body temperature
680
2.81 why is homeostasis critically important
it ensures the maintenance of optimal conditions for enzyme action and cell function
681
2.81 examples of physiological factors that are controlled by homeostasis in mammals include
core body temperature metabolic waste (e.g. carbon dioxide and urea) blood pH the concentration of glucose in the blood the water potential of the blood the concentration of respiratory gases (carbon dioxide and oxygen) in the blood
682
2.81 homeostatic mechanisms in mammals require
information to be transferred between different parts of the body
683
2.81 what are the two communication systems in mammals that require information to be transferred to different parts of the body
the nervous system the endocrine system
684
2.81 homeostasis is what
the control or regulation of the internal conditions of a cell or organisms
685
2.81 examples of homeostasis of internal conditions
water content (of an individual cell or of the body fluids of an organism) temperature pH blood pressure blood glucose concentration
686
2.81 why is it important for an organism to keep internal conditions within set limits
to ensure they stay healthy and maintain optimum conditions to allow the organism to function in response to internal and external changes
687
2.81 if the internal conditions of homeostasis exceed the set limits
the organism may die
688
2.81 homeostasis maintains optimal conditions for what
enzyme action and all cell functions
689
2.81 homeostasis ensures
hat reactions in body cells can function and therefore the organism as a whole can live
690
2.81 the core body temp of humans is kept close to
37 degrees celsius
691
2.81 why core body temp of humans kept close to 37
a temperature change would stop essential enzymes from functioning optimally
692
2.81 to keep the body temp at 37 the human body must be able to
make a coordinated response to any rise or fall in body temperature
693
2.81 body temperature is monitored and controlled by what
the thermoregulatory centre in base of the brain as blood passes through it
694
2.81 the thermoregulatory centre contains what
receptors that are sensitive to the temperature of the blood
695
2.81 the skin also contains temperature receptors and
sends nervous impulses to the thermoregulatory centre the brain then coordinates a cooling or heating response depending on what is required
696
2.81 water loss via the lungs - during breathing - or skin - during sweating - cannot
be controlled
697
2.81 the volume of water lost in the production of urine
can be controlled by the kidneys
698
2.81 water can be reabsorbed from the filtrate as it passes along the collecting ducts
if the water content of the blood is too high then less water is reabsorbed, if it is too low then more water is reabsorbed this causes either a large amount of dilute urine to be produced, or a small amount of concentrated urine a hormone called ADH controls this process
699
2.82 a co-ordinated response requires
a stimulus, a receptor and an effector
700
2.82 homeostasis is under what type of control
involuntary / automatic
701
2.82 what does involuntary / automatic control mean
the brain stem (or non-conscious part of the brain) and the spinal cord are involved in maintaining homeostasis – you don’t consciously maintain your body temperature or blood glucose level
702
2.82 automatic control systems involve
nervous responses or chemical responses e.g. hormones
703
2.82 all control systems that carry out a coordinated response require what
a stimulus a receptor a coordination centre an effector
704
2.82 what is the stimulus
a change in the environment e.g. a change in glucose levels in the blood, a change in body temperature etc
705
2.82 what is the receptor
receptor cells that detect stimuli
706
2.82 what is the coordination centre
the brain, spinal cord and pancreas, which receives and processes information from receptors
707
2.82 what is an effector
a muscle or gland, which brings about responses to restore optimum levels
708
2.82 a coordinated response such as what
stuff required when there is not enough water in the blood
709
2.83 plants respond to what
stimuli
710
2.83 plants need to be able to grow in response to certain
stimuli
711
2.83 plants need to be able to grow in response to what
light
712
2.83 plants need to be able to grow in response to
light or gravity
713
2.83 why do plants grow in response to light
to ensure their leaves can absorb light for photosynthesis
714
2.83 why do plants grow in response to gravity
to ensure that shoots grow upwards and roots grow downwards
715
2.83 what are the directional growth responses made by plants - in response to light / gravity - known as
tropisms
716
2.83 what are tropisms
the directional growth responses made by plants in response to light and gravity
717
2.83 if growth is towards the stimulus in plants the tropism is
positive
718
2.83 if growth is away from the stimulus in plants the tropism is
negative
719
2.83 what does it mean if the tropism is positive
the growth is towards the stimulus
720
2.83 what does it mean if the tropism is negative
the growth is away from the stimulus
721
2.84 a response to light in a plant is
phototropism
722
2.84 a response to gravity in a plant is
geotropism (or gravitropism)
723
2.84 as the shoot grows upwards, away from gravity & towards light shoots show
a positive phototropic response and a negative geotropic response
724
2.84 give an example of a positive phototropic response and a negative geotropic response
when a shoot grows upwards, away from gravity and towards the light - so leaves are able to absorb sunlight
725
2.84 as roots grow downwards into the soil away from light and towards gravity shoots show
a negative phototropic response and a positive geotropic response
726
2.84 give an example of a negative phototropic response and a positive geotropic response
when a shoot grows downwards, away from the light and into the soil, towards gravity - in order to anchor the plant and absorb water and minerals from the soil
727
2.84 stimulus of light give the name of response positive response negative response
phototropism growth towards the light source - shoots growth away from the light source - roots
728
2.84 stimulus of gravity give the name of response positive response negative response
geotropism growth towards source of gravity - roots growth away from source of gravity - shoots
729
2.84 definition of phototropism
growth towards or away from the direction of the light source
730
2.84 definition of geotropism
growth towards or away from the source of gravity
731
2.85 plants produce what ? for growth responses
plant growth regulators (similar to hormones in animals)
732
2.85 what are plant growth regulators called
auxins
733
2.85 why do plants produce auxin
to coordinate and control directional growth responses such as phototropisms and geotropisms
734
2.85 what is a plant growth regulator
auxin
735
2.85 why do plants produce plant growth regulators
to coordinate and control directional growth responses such as phototropisms and geotropisms
736
2.85 what is auxin
a plant growth regulator
737
2.85 what coordinates & controls directional growth responses such as phototropisms and geotropisms
auxin
738
2.85 auxin coordinates & controls directional growth response such as
phototropisms and geotropisms
739
2.85 auxin is mostly made where
in the tips of growing shoots and then diffuses down into the region where cell division occurs
740
2.85 why is the region behind the tip of a shoot important
it is the only region that is able to contribute to growth by cell division and cell elongation
741
2.85 auxin stimulates the region behind the tip of the shoot to
elongate
742
2.85 the more auxin there is
the faster the cells will elongate and grow
743
2.85 if light shines around the tip of a shoot, auxin is distributed
evenly throughout
744
2.85 if light shines around the tip of a shoot, auxin means the cells in the shoot grow
at the same rate
745
2.85 if light shines predominantly on one side of a shoot, auxin is distributed
and concentrates on the shaded side
746
2.85 if light shines predominantly on one side of a shoot, auxin means the cells in the shoot grow
and elongate on the shaded side, and grow faster than the cells on the sunny side
747
2.85 unequal growth on either side of the shoot causes
the shoot to bend and grow in the direction of the light
748
2.85 positive phototropism in plants shoots is a result of
auxin accumulating on the shaded side of a shoot
749
2.85 what is better to write in relation to phototropism / geotropism instead of 'grows towards the light'
cell elongation
750
2.86 there are two different control systems in humans that work together to do what
respond to stimuli
751
2.86 what are the two different control systems that respond to stimuli
the nervous system the hormonal system - also known as the endocrine system
752
2.86 changes in our external environment or in the internal environment of our bodies act as
stimuli
753
2.86 the nervous and hormonal systems do what to stimuli
coordinate a suitable response to stimuli
754
2.86 what allows us to coordinate and regulate body functions
our systems coordinating to make a suitable response to stimuli - external / internal environment
755
2.86 the nervous system & endocrine / hormonal system allow us to do what
to coordinate and regulate body functions by making a suitable response to stimuli - external / internal environment
756
2.86 information is sent through the nervous system as what
electrical impulses
757
2.86 what are electrical impulss
electrical signals that pass along nerve cells known as neurones
758
2.86 what are nerve cells known as in the nervous system
neurones
759
2.86 impulses that travel along neurones travel at
very high speeds up to 100 metres per second
760
2.86 what allows rapid responses to stimuli in the nervous system
the impulses travelling at very high speeds along neurones
761
2.86 what is an example of a rapid response to stimuli
the withdrawal reflex which causes you to move your hand away fast when it touches a flame
762
2.86 the nervous system coordinates the activities of what receptors
sensory receptors
763
2.86 what are the three thing the nervous system coordinates activity for
sensory receptors, decision-making centres in the central nervous system and effectors such as muscles and glands
764
2.86 the nervous system coordinates the activities of decision-making centres in what
the central nervous system
765
2.86 the nervous system coordinates the activities of muscles and glands which are
effectors
766
2.86 the nervous system is used to
control functions that need instant or very rapid responses
767
2.86 information is sent through the endocrine system as
chemical substances known as hormones
768
2.86 hormones are carried by what
the blood and therefore can circulate around the whole body
769
2.86 hormones transmit information from one part of the organism to another and bring about what
a change - they provide a signal that triggers a response
770
2.86 hormones alter what
they alter the activity of one or more specific target organs
771
2.86 what are hormones used to control functions
that do not need instant responses
772
2.86 hormones are produced by what
endocrine glands
773
2.86 the endocrine glands that produce hormones in animals are collectively known as the
endocrine system
774
2.86 what is a gland
a group of cells that produces and releases one or more substances (a process known as secretion
775
2.86 comparison between nervous & endocrine system 1. made of 2. type of message 3. speed of action 4. duration of effect
1. N: nerves, brain & spinal cord E: glands 2. N: electrical E: chemical hormone 3. N: very fast E: slower 4. N: short - until the nerve impulses stops 4. E: long until the hormone is broken down in the body
776
2.86 comparison between nervous & endocrine system made up of
N: nerves, brain & spinal cord E: glands
777
2.86 comparison between nervous & endocrine system type of message
N: electrical E: chemical hormone
778
2.86 comparison between nervous & endocrine system speed of action
N: very fast E: slower
779
2.86 comparison between nervous & endocrine system duration of effect
N: short - until the nerve impulses stops E: long until the hormone is broken down in the body
780
2.86 what are nerves
bundles of neurones
781
2.87 what does the central nervous system consist of
the brain and spinal cord which is linked to the organs by nerves
782
2.87 the human nervous system consists of
CNS - the central nervous system, the brain an spinal cord PNS - the peripheral nervous system, all of the nerves in the body
783
2.87 information is sent through the nervous system as
electrical impulses - electrical signals that pass along nerve cells known as neurones
784
2.87 a bundle of neurones is known as what
a nerve
785
2.87 the nerves spread out from the central nervous system to
all other regions of the body and to all the sense organs
786
2.87 the CNS acts as
a central coordinating centre for the impulses that come in from or are sent out to any part of the body
787
2.88 stimulation of receptors in the sense organs send what
electrical impulses along nerves into and out of the central nervous system resulting in rapid responses
788
2.88 what results in rapid responses
stimulation of receptors in the sense organs send electrical impulses along nerves into and out of the central nervous system
789
2.88 a stimulation of receptors in the sense organs sends what
electrical impulses along nerves into and out of the central nervous system, resulting in rapid responses
790
2.88 what is the pathway through the nervous system
stimulus → sensory neurone → relay neurone → motor neurone → effector → response
791
2.88 what is a stimulus received by
a stimulus is received by a sensory (receptor) neurone
792
2.88 what are most receptors specialised to
most receptors are specialised to detect particular stimuli
793
2.88 what happens when a receptor is stimulated
it produces electrical impulses
794
2.88 where do the impulses travel to along the sensory neurone
to the central nervous system the coordinator is either the brain or the spinal cord
795
2.88 in the central nervous system the impulses are passed on to what
a relay neurone
796
2.88 the relay neurone links to what
a motor neurone
797
2.88 when the relay neurone links to a motor neurone the impulses travel along it until
they reach the effector
798
2.88 what is the effector
its what carries out the response
799
2.88 what may an effector be
a muscle or gland
800
2.88 describe the nerve pathway from stimulus to response
- stimulus - is detected by receptor - sensory neurone - relay neurone - CNS - motor neurone - impulses are sent along the sensory neurone, then the relay neurone and then the motor neurone - the impulses received by effector - response
801
2.89 neurones do not do what
they do not go into direct contact with eachother
802
2.89 what are dendrites
branched nerve fibres which receive nerve impulses and pass them towards a cell body
803
2.89 the dendrites of two neurones meet to make what
to make a connection between the neurones
804
2.89 when two dendrites meet what is formed
a junction known as a synapse
805
2.89 what is a synapse
where the axon of one neurone connects with the dendrite of another or an effector they help coordinate activities and are unidirectional
806
2.8 what is an axon
a single nerve fibre that carries nerve impulses away from a cell body
807
2.89 at a synapse there is what
a very small gap between the neurones
808
2.89 what is the gap between neurones called
the synaptic cleft or synaptic gap
809
2.89 electrical impulses cannot what
travel directly from one neurone to the next due to the synaptic gap
810
2.89 can electrical impulses travel directly from one neurone to the next
no due to the synaptic gap
811
2.89 electricity can/cannot do what with the synaptic gap
electricity cannot jump the gap
812
2.89 for electrical impulses to transfer
the electrical signal is briefly converted to a chemical signal that can cross the synaptic gap
813
2.89 what can pass in the synaptic gap
a chemical signal known as neurotransmitters
814
2.89 to pass the synaptic gap the electrical signal is converted to what
a chemical signal
815
2.89 what is the chemical signalling molecules called
neurotransmitters
816
2.89 what are neurotransmitters
chemical signalling molecules that are used to transfer the signal between neurones at a synapse that can cross the synaptic gap
817
2.89 what are the chemical signalling molecules used for
to transfer the signal between neurones at a synapse
818
2.89 when the neurotransmitters meet the neurone on the opposite side the signal is converted back
back into an electrical impulse which can then pass along the neurone
819
2.89 the electrical impulse travels along the
axon of the first neurone
820
2.89 what is the presynaptic neurone
the axon of the first neurone
821
2.89 when the electrical impulse travels along the axon of the first neurone / presynaptic neurone what does it trigger
it triggers the end of the presynaptic neurone to release chemicals called neurotransmitters from vesicles
822
2.89 what do vesicles fuse with
the presynaptic membrane, releasing their contents into the synaptic gap
823
2.89 the neurotransmitters diffuse across the synaptic gap and bind with what
bind with receptor molecules on the membrane of the second neurone known as the postsynaptic membrane
824
2.89 what is the postsynaptic membrane
the membrane on the second neurone
825
2.89 after the neurotransmitters diffuse across the synaptic gap and bind with receptor molecules on the postsynaptic membrane what is stimualted
it stimulates the second neurone to generate an electrical impulse which then travels down the second axon
826
2.89 the neurotransmitters are destroyed to prevent what
continued stimulation of the second neurone - otherwise the neurotransmitters would cause repeated impulses to be sent
827
2.89 to prevent continued stimulation of the impulses,w hat happens to the neurotransmitters
they are destroyed
828
2.89 synapses ensure impulses can what
only travel in one direction
829
2.89 pathway of how an impulse is passed on at a synapse
1. an impulse arrives at the end of the presynaptic neurone 2. vesicles move towards & fuse with the presynaptic membrane this releases neurotransmitters into the synaptic gap 3. the neurotransmitters diffuse across the synaptic gap - down a concentration gradient 4. neurotransmitters attach the to receptors on the postsynaptic membrane 5. this triggers an impulse which travels along the postsynaptic neurone 6. the neurotransmitters are recycled or destroyed once an impulse is sent
830
2.89 neurotransmitters move by what
diffusion which requires a concentration gradient & is a passive process
831
2.89 receptors that are complementary in shape to neurotransmitters are located where
on the postsynaptic neurone
832
2.89 drugs such as heroin, ecstasy & cocaine can bind to neurotransmitter receptors that what
triggers impulses in different regions of the brain
833
2.90 what is a reflex response also known as
an involuntary response
834
2.90 a reflex response does not involve what
the conscious part of the brain as the coordinator of the reaction
835
2.90 awareness of a response happens when
after the response has been carried out
836
2.90 responses are what
automatic and rapid
837
2.90 what helps minimise damage to the body and aids survival
responses are automatic and rapid
838
2.90 why are automatic and rapid responses helpful
they minimise danger to the body and aid survival
839
2.90 name examples of reflex responses that help us avoid serious injury
pain-withdrawal, blinking, and coughing
840
2.90 the reflex arc is what
the pathway of reflex response
841
2.90 reflex arc pathway
stimulus -> receptor -> sensory neurone -> intermediate relay neurone -> motor neurone -> effector -> response
842
2.90 what is the pathway taken by electrical impulses as they travel along neurones
stimulus -> receptor -> sensory neurone -> intermediate relay neurone -> motor neurone -> effector -> response
843
2.90 give the example of the reflex response when someone stands on a pin
- the pin (the stimulus) is detected by a - (pain/pressure/touch) receptor in the skin on the person's foot - a sensory neurone sends electrical impulses to the spinal cord (the coordinator) - an electrical impulse is passed to a relay neurone in the spinal cord (part of the CNS) - a relay neurone synapses with a motor neurone - a motor neurone carries an impulse to a muscle in the leg (the effector) - when stimulated by the motor neurone, the muscle will contract and pull the foot up and away from the sharp object (the response)
844
2.91 the eye is what
a highly specialised sense organ containing receptor cells that allow us to detect the stimulus of light
845
2.91 the retina of the eye contains what
two types of receptor cells
846
2.91 what are two types of receptor cells in the retina
rods and cones
847
2.91 which receptor cells in the eye are sensitive to light
the rods
848
2.91 which receptor cells can detect colour
the cones
849
2.91 the eye is a sense organ that contains what
light receptor cells
850
2.91 what type of organ is the eye
a sense organ
851
2.91 what are the structures in the eye
cornea iris lens retina optic nerve pupil conjunctiva ciliary muscle suspensory ligaments sclera fovea blind spot
852
2.91 describe the structure of the cornea
a transparent lens that refracts light as it enters the eye
853
2.91 describe the structure of the iris
controls how much light enters the pupil
854
2.91 describe the structure of the lens
transparent disc that can change shape to focus light onto the retina
855
2.91 describe the structure of the retina
contains light receptor cells – rods (detect light intensity) and cones (detect colour)
856
2.91 describe the structure of the optic nerve
sensory neuron that carries impulses between the eye and the brain
857
2.91 describe the structure of the pupil
hole that allows light to enter the eye
858
2.91 describe the structure of the conjunctiva
a clear membrane that covers the white of the eye and the inside of the eyelids; it lubricates the eye and provides protection from external irritants
859
2.91 describe the structure of the ciliary muscle
a ring of muscle that contracts and relaxes to change the shape of the lens
860
2.91 describe the structure of the suspensory ligaments
ligaments that connect the ciliary muscle to the lens
861
2.91 describe the structure of the sclera
the strong outer wall of the eyeball that helps to keep the eye in shape and provides a place of attachment for the muscles that move the eye
862
2.91 describe the structure of the fovea
a region of the retina with the highest density of cones (colour detecting cells) where the eye sees particularly good detail
863
2.91 describe the structure of the blind spot
the point at which the optic nerve leaves the eye, where there are no receptor cells
864
2.92 what is the function of the eye
focusing on near and distant objects
865
2.92 the way the lens brings about fine focusing is called what
accommodation
866
2.92 what is accommodation
the way the lens brings about fine focusing
867
2.92 what shape and texture is the lens
it is elastic and its shape can be changed
868
2.92 how can the lens shape be changed
the suspensory ligaments attached to it become tight or loose
869
2.92 how does the lens change shape
the changes are brought about by the contraction or relaxation of the ciliary muscles
870
2.92 what happens when the ciliary muscles contract or relax
the lens changes shape
871
2.92 what happens in the eye when an object is close up
the ciliary muscles contract (the ring of muscle decreases in diameter) this causes the suspensory ligaments to loosen this stops the suspensory ligaments from pulling on the lens, which allows the lens to become fatter light is refracted more
872
2.92 what is the result when an object is close to the eye
light is refracted more by lens to focus on near objects
873
2.92 what happens in the eye when an object is far away
the ciliary muscles relax (the ring of muscle increases in diameter) this causes the suspensory ligaments to tighten the suspensory ligaments pull on the lens, causing it to become thinner light is refracted less
874
2.92 what is the result when an object is far away from the eye
light is refracted less allowing the eye to focus on a distant object
875
2.92 what happens to the ciliary muscles, suspensory ligaments, lens and light refraction when the eye focuses on near objects
ciliary muscles: contracted suspensory ligaments: loose lens: fatter light refraction: more
876
2.92 what happens to the ciliary muscles, suspensory ligaments, lens and light refraction when the eye focuses on distant objects
ciliary muscles: relaxed suspensory ligaments: tight lens: thinner light refraction: less
877
2.92 the suspensory ligaments are not muscles so you cannot say they contract or relax, instead what do you say
tighten or loosen
878
2.92 the pupil reflex is what
a reflex action
879
2.92 why does the pupil reflex
to protect the retina from damage
880
2.92 to protect the retina from damage the pupil does what
the pupil has a reflex action called the pupil reflex
881
2.92 what happens to the pupil in dim light
the pupil dilates (widens) in order to allow as much light into the eye as possible to improve vision
882
2.92 what happens to the pupil in bright light
the pupil constricts (narrows) in order to prevent too much light from entering the eye and damaging the retina
883
2.92 in what type of light does the pupil dilate
dim light
884
2.92 in what type of light does the pupil constrict
bright light
885
2.92 what happens to the radial muscles of the iris, the circular muscles of the iris and the pupil in dim light
radial muscles of the iris: contracted circular muscles of the iris: relaxed pupil is: dilated - light enters eye
886
2.92 what happens to the radial muscles of the iris, the circular muscles of the iris and the pupil in bright light
radial muscles of the iris: relaxed circular muscles of the iris: contracted pupil is: constricted - less light enters eye
887
2.92 explain the eye in a dark environment
photoreceptors detect the change in environment to being dark radial muscles contract circular muscles relax pupil dilates more light enters the eye
888
explain the pupil reflex in regard to bright light
radial muscles: relaxed circular muscles: contracted pupil size: narrow light entering eye: less
889
2.92 explain the eye in a bright environment
photoreceptors detect the change in environment to being bright radial muscles relax circular muscles contract pupil constricts less light enters the eye
890
explain the pupil reflex in regard to dim light
radial muscles: contracted circular muscles: relaxed pupil size: wide light entering eye: more
891
2.93 the skin is what
our largest sense organ
892
2.93 what does the skin contain that lets us detect external stimuli
many different receptors
893
2.93 why does the skin contain many different receptors
it allows us to detect various external stimuli including touch, pressure, pain, heat and cold
894
2.93 give examples of external stimuli our skin can detect
touch, pressure, pain, heat and cold
895
2.93 structures in the skin also do what
they play an important role in regulating body temperature - an example of homeostasis
896
2.93 mention the structures in the skin that can increase or reduce heat loss to the surroundings
muscles fatty tissue arteriole sensory neurone sweat gland dermis capillaries muscle epidermis free nerve ending sweat pore hair check save my exams diagram - skin and temperature
897
2.93 what are the cooling mechanisms in humans - non detailed
vasodilation of skin capillaries sweating flattening of hairs
898
2.93 what are the cooling mechanisms in humans - detailed
vasodilation of skin capillaries heat exchange (both during warming and cooling) occurs at the body's surface as this is where the blood comes into closest proximity to the environment one way to increase heat loss is to supply the capillaries in the skin with a greater volume of blood, which then loses heat to the environment via radiation arterioles (small vessels that connect arteries to capillaries) have muscles in their walls that can relax or contract to allow more or less blood to flow through them during vasodilation, these muscles relax, causing the arterioles near the skin to dilate (get wider) and allowing more blood to flow through capillaries sweating sweat is secreted by sweat glands this cools the skin by evaporation which uses heat energy from the body to convert liquid water into water vapour flattening of hairs the hair erector muscles in the skin relax, causing hairs to lie flat this stops them from forming an insulating layer by trapping air and allows air to circulate over the skin and allows heat to leave by radiation
899
2.93 describe the vasodilation of skin capillaries for the cooling mechanism in humans
heat exchange occurs at the body's surface as this is where the blood is closest proximity to the environment one way to increase heat loss is to supply the capillaries in the skin with a greater volume of blood which then loses heat to the environment via radiation arterioles have muscles in their walls that can relax causing the arterioles near the skin to dilate and allows more blood to flow through capillaries
900
2.93 describe sweating for the cooling mechanism in humans
sweat is secreted by sweat glands this cools the skin by evaporation which uses heat energy from the body to convert liquid water into water vapour
901
2.93 describe the flattening of hairs for the cooling mechanism in humans
the hair erector muscles in the skin relax, causing hairs to lie flat this stops them from forming an insulating layer by trapping air and allows air to circulate over the skin and allows heat to leave by radiation
902
2.93 describe the responses in the skin when the body temperature is too high and needs to decrease
sweat glands excrete sweat which cools the skin as it evaporates hair erector muscles will relax vessels dilate to increase blood flow to the skin
903
2.93 what are the warming mechanisms in humans - non detailed
vasoconstriction of skin capillaries shivering erection of hairs
904
2.93 what are the heating mechanisms in humans - detailed
vasoconstriction of skin capillaries one way to decrease heat loss is to supply the capillaries in the skin with a smaller volume of blood, minimising the loss of heat to the environment via radiation during vasoconstriction, the muscles in the arteriole walls contract, causing the arterioles near the skin to constrict (get smaller) and allowing less blood to flow through capillaries vasoconstriction is not, strictly speaking, a 'warming' mechanism as it does not raise the temperature of the blood but instead reduces heat loss from the blood as it flows through the skin shivering this is a reflex action in response to a decrease in core body temperature muscles contract in a rapid and regular manner the exothermic metabolic reactions required to power this shivering generate sufficient heat to warm the blood and raise the core body temperature erection of hairs the hair erector muscles in the skin contract, causing hairs to stand on end this forms an insulating layer over the skin's surface by trapping air between the hairs and stops heat from being lost by radiation
905
2.93 describe the vasoconstriction of skin capillaries for the heating mechanism in humans
one way to decrease heat loss is to supply the capillaries in the skin with a smaller volume of blood - this minimises the heat loss to the environment via radiation
906
2.93 describe shivering for the heating mechanism in humans
this is a reflex action in response to a decrease in core body temperature muscles contract in a rapid & regular manner the exothermic metabolic reactions required to power this shivering generate sufficient heat to warm the blood and raise the core body temperature
907
2.93 describe the erection of hairs for the heating mechanism in humans
the hair erector muscles in the skin contract this causes the hairs to stand on end this forms an insulating layer over the skins surface by trapping air between the hairs and stops heat from being lose by radiation
908
2.93 describe the responses in the skin when the body temperature is too low and needs to increase
the hair stands upright trapping the air around the skin trapped air is an excellent insulator hair erector muscles will contract vessels constrict reducing blood flow to the skin remember - heat energy transfer always occurs from hotter regions to cooler regions radiation is heat energy transfer by electromagnetic radiation conduction and convection are the other two types
909
2.93 what is the core body temperature of humans kept close to
37 degrees celsius
910
2.93 why is the core body temperature of humans kept close to 37 degrees celcius
it is tightly controlled as a change in core body temperature of more than 2 degrees celsius can be fatal
911
2.93 to keep the body at a core body temperature the human body must be able to do what
make a coordinated response to any rise or fall in body temperature
912
2.93 temperature recepters are also known as what
thermoreceptors
913
2.93 what are thermoreceptors also known as
temperature receptors
914
2.93 where are the temperature receptors / thermoreceptors found
in the skin and hypothalamus
915
2.93 what can detect minute changes in body temperature
temperature receptors or thermoreceptors
916
2.93 what do the temperature receptors / thermoreceptors do
they detect minute changes in body temperature
917
2.93 the brain does what when there is a change in body temperature
the brain coordinates a cooling or heating response depending on what is required
918
2.93 temperature regulation is an example of what
homeostasis
919
2.93 what happens when there is an increase in body temperature
thermoreceptors in the hypothalamus and skin can detect change this leads to increased sweating, vasodilation & hairs lie flat against the skin this leads to a decrease in body temperature
920
2.93 what happens when there is an decrease in body temperature
thermoreceptors in the hypothalamus and skin detect change this leads to shivering, vasoconstriction & skin hairs erect this leads to an increase in body temperature
921
2.94 what is a hormone
it is a chemical substance produced by a gland and carried by the blood which alters the activity of one or more specific target organs
922
2.94 what do hormones do
they are chemicals that transmit information from one part of the organism to another and bring about a change
923
2.94 what are the important hormones
adrenaline insulin testosterone progesterone oestrogen
924
2.94 what is adrenaline known as
the fight or flight hormone as it is produced in situations where the body may be in danger
925
2.94 what does adrenaline cause
a range of different things to happen in the body, all designed to prepare it for movement
926
2.94 what does adrenaline do to the body - non-detailed
an increase in heart & breathing rate diverts blood flow towards muscles dilation of the blood vessels inside muscles breaks down stored glycogen into glucose
927
2.94 what does adrenaline do to the body - detailed
increase in heart rate and breathing rate - ensures glucose and oxygen can be delivered to muscle cells (and carbon dioxide can be taken away from muscles cells) at a faster rate diverting blood flow towards muscles and away from non-essential parts of the body such as the alimentary canal - ensures an increased supply of the reactants of respiration (glucose and oxygen) dilation of the blood vessels inside muscles - ensures more blood can circulate through them (again, supplying more glucose and oxygen) breaking down of stored glycogen to glucose in the liver and muscle cells, with glucose released by the liver being transported to active muscle cells - ensures a higher blood glucose concentration for increased respiration in muscle cells (providing greater energy for movement)
928
2.94 blood glucose concentration is an example of what
homeostasis
929
2.94 too high a level of glucose in the blood can lead to what
the cells of the body losing water by osmosis which can be dangerous
930
2.94 too low of glucose in the blood can lead to what
the brain receiving insufficient glucose for respiration potentially leading to a coma or even death
931
2.94 what works together to control blood glucose levels
the pancreas and liver
932
2.94 the pancreas and liver work together to do what
control blood glucose level
933
2.94 what happens if the blood glucose concentration gets too high
cells in the pancreas detect the increased blood glucose levels the pancreas produces the hormone insulin, secreting it into the blood insulin stimulates muscles and the liver to take up glucose from the bloodstream and store it as glycogen (a polymer of glucose) this reduces the concentration of glucose in the blood back to normal levels, at which point the pancreas stops secreting insulin
934
2.94 to maintain blood glucose levels the pancreas acts as what and does what
the pancreas acts as an endocrine gland (making and secreting hormones into the bloodstream)
935
2.94 explain the regulation of blood glucose levels
- blood glucose levels rise - pancreas releases insulin - insulin stimulates uptake of glucose into the liver - liver stores excess glucose as glycogen - blood glucose levels reduce
936
2.94 where is testosterone produced
in the male testes
937
2.94 what is testosterone responsible for
the development of secondary sexual characteristics in males
938
2.94 what is responsible for the development of secondary sexual characteristics in males
testosterone
939
2.94 where is progesterone produced
in the female ovaries
940
2.94 what is progesterone responsible for
maintaining the uterine lining during pregnancy
941
2.94 what is responsible for for maintaining the uterine lining during pregnancy
progesterone
942
2.94 where is oestrogen produced
in the female ovaries
943
2.94 what is oestrogen responsible for
for the development of secondary sexual characteristics in females and regulating the menstrual cycle
944
2.94 what is responsible for the development of secondary sexual characteristics in females and regulating the menstrual cycle
oestrogen
945
2.94 adrenaline source, role and effect
adrenal gland readies the body for a 'fight or flight' response increases heart and breathing rate
946
2.94 where is adrenaline produced
adrenal gland
947
2.94 insulin source, role and effect
pancreas lowers blood glucose levels causes excess glucose in the blood to be taken up by the muscles and liver and converted into glycogen for storage
948
2.94 testosterone source, role and effect
testes main sex hormone in males development of male reproductive organs and secondary characteristics
949
2.94 progesterone source, role and effect
ovaries maintains pregnancy maintains the uterus lining to cushion the fertilised egg and allow it to develop
950
2.94 oestrogen source, role and effect
ovaries main sex hormone in females development of female secondary sexual characteristics and regulation of the menstrual cycle
951
2.95B what are the three advanced hormones you need to know
ADH antidiuretic hormone FSH follicle-stimulating hormone LH luteinising hormone
952
2.95B what does ADH stand for
antidiuretic hormone
953
2.95B what does FSH stand for
follicle-stimulating hormone
954
2.95B what does LH stand for
luteinising hormone
955
2.95B ADH if the water content of the blood falls below a certain level
the blood is too concentrated receptors detect this and stimulate the pituitary gland to release more ADH this causes the collecting ducts of the nephrons to become more permeable to water this leads to more water being reabsorbed from the collecting ducts the kidneys produce a smaller volume of urine that is more concentrated (contains less water)
956
2.95B ADH if the water content of the blood rises above a certain level
the blood is too dilute receptors detect this and stimulate the pituitary gland to release less ADH this causes the collecting ducts of the nephrons to become less permeable to water this leads to less water being reabsorbed from the collecting ducts the kidneys produce a larger volume of urine that is less concentrated (contains more water)
957
2.95B ADH source, role and effect
pituitary gland controlling the water content of the blood increases the permeability of the collecting ducts in the kidneys to water, increasing the reabsorption of water back into the blood
958
2.95B FSH source, role and effect
pituitary gland causes ovary to develop a mature egg cell stimulates the development of egg cells in the ovary and the release of oestrogen
959
2.95B LH source, role and effect
pituitary gland causes ovary to release a mature egg cell stimulates the release of an egg cell from the ovary (ovulation) and the release of progesterone