Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

VPH 122 > 2. Coronavirus > Flashcards

2. Coronavirus Flashcards

1
Q

Major cause of coronavirus

A

travel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Coronavirus

  • enveloped / non-enveloped?
  • RNA / DNA virus?
  • singe/double stranded?
A

enveloped
RNA virus
single-stranded

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Coronavirus

Order:
Family:
Genera:

A

Order: Nidovirales

Family: Coronaviridae

Genera:
1) Alpha-CoV
2) Beta-CoV***
3) Delta-CoV
4) Gamma-CoV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Subgenus of SARS

A

Sarbecovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Subgenus of MERS

A

Merbecovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SARS-CoV

reported case: _____
deaths: _____
countries: _____

A

reported case: 8,096

deaths: 774 (~9.6% case fatality)

countries: 37

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where SARS-CoV originated

A

Guangdong Province, China

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Time span of SARS-CoV

A

November 2002 – July 2003

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Other term for SARS-CoV

A

“Infectious atypical pneumonia”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

New coronavirus not previously endemic in humans

A

SARS-CoV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cases of SARS-CoV had epidemiological links
to the ____-___ animal trade.

A

wild-game animal trade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Specimens are collected from
1)
2)

(also give scientific name)

A
  1. masked palm civet
    (Paguma larvata)
  2. raccoon dogs
    (Nyctereutes procyonoides)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SARS CoV like virus with more than ___% nucleotide homology to the human SARS CoV

A

99% nucleotide homology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Middle East Respiratory Syndrome coronavirus (MERS)

reported case: _____
deaths: _____
countries: _____

A

reported case: “2,604”

deaths: “936” (~36% case fatality)

countries: “27”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where MERS originated

A

Saudi Arabia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Time span of MERS

A

Sept 2012 - present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

98-100% of ____ are (+) for MERS-CoV antibodies

A

camels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Incidence of MERS-CoV in humans is 15x higher in _______

A

camel shepherd

19
Q

Incidence of MERS-CoV in humans is 23x higher in ____ __ than in general population.

A

slaughterhouse workers

20
Q

Where COVID-19 originated

A

Wuhan, Hubei Province, China

21
Q

Time span of COVID-19

A

Devember 2019 - present

22
Q

was found to be an epidemiological link of the 100 initial patients exposed (COVID-19)

A

Wuhan Huanan Seafood Wholesale (Wet Market)

23
Q

CoV attach to the host cell surface receptors via _____

A

spike protein (S)

24
Q

______ is believed to play a crucial role in overcoming species barriers and accomplishing interspecies transmission from animals to human

A

S protein

25
Q

Cellular receptor of SARS-CoV & COVID-19

A

ACE 2

angiotensin-converting enzyme 2

26
Q

Cellular receptor of MERS-CoV

A

DPP4

dipeptidyl peptidase 4

27
Q

Reservoir hosts of:

SARS-CoV: ______
MERS-CoV: ______
COVID-19: ______

A

Reservoir hosts

SARS-CoV: Horshoebat

MERS-CoV: Egyptian tomb bat

COVID-19: Bats

28
Q

Coronavirus infection in “humans” is commonly associated with (5)

A

1) mild to severe respiratory disease
2) high fever
3) severe inflammation
4) cough
5) internal organ dysfunction

29
Q

Coronavirus infection in “domestic animals” is commonly associated with (4)

A

1) respiratory
2) gastrointestinal
3) liver disease
4) neurologic disease

30
Q

INCUBATION PERIOD (IP)

SARS-CoV: _______
MERS-CoV: _______
COVID-19: _______

A

SARS-CoV: [ 2 - 10 days ]

MERS-CoV: [ 2 - 10 days ]
average: ( 5 - 6 days )
death: [~11.5 days ]

COVID-19: [ 4-7 days ]
average: ( 5 days )

31
Q

number 1 Clinico-pathological feature of coronavirus

A

fever

32
Q

Recommended diagnosis for coronavirus

A

RT-PCR / next generation sequencing

33
Q

For viral pneumonia (coronavirus)

A

Chest CT

34
Q

Viral RNA could be detected in (5) of covid infected persons

A
  1. respiratory tract (URT)
  2. lower respiratory tract
  3. stool
  4. blood
  5. urine
35
Q

Peak of coronavirus viral load in respiratory specimens

A

second (2nd) weeek after symptom onset

36
Q

Which respiratory tract has higher viral load of coronavirus?

A

LOWER respiratory tract

37
Q

Diagnostic classification for coronavirus

A

virological culture

38
Q

Where coronavirus test can be done

A

RITM

39
Q

Specimen required for coronavirus

A

respiratory discharges

40
Q

(3) best recommendation for clinical specimens for detection of SARS-CoV 2

A
  • bronchalveolar lavage fluid
  • sputum
  • nasal swabs
41
Q

Epidemiological tools for control of coronavirus (4)

[ ETPI ]

A
  1. Early warning system surveillance
  2. Tracking & mapping by GIS / geographical information system
  3. Prediction tools/models
  4. Immediate travel restrictions
42
Q

Category of SARS & MERS as notifiable disease (reported by PIDSR)

A

Category 1

43
Q

Control and Prevention of coronavirus

A
  1. Vaccination ***
  2. Immediate travel restrictions
  3. Ban on wildlife trade
  4. PPE
  5. Hand hygiene
  6. Improve measures in hospital

VPH 122 (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions