1st Exam. Part 10. ANTISEPTICS Flashcards
- Ideal : Minimal cytotoxicity
- Decrease bacterial counts
- May remove necrosis or debris
- For superficial wounds only (skin)
Antiseptics
it could delay wound healing for longer periods of time (7-10 days)
ideal: 5 days
Povidone iodine
0.5 % Sodium hydrogen chloride (1:9 bleach/detergent to sodium chloride ratio)
may kill neutrophils
Dakin’s solution
used in cases for spore forming bacteria like Clostridium and Bacillus
Hydrogen peroxide
Could be applied systematically, oral, topical
(superficial)
Antibiotics
effective in the control of bacterial growth in superficial wounds
Topical antibiotics
effective in deep wounds
Echoes therapeutic levels within 3 hours after administration
Systemic antibiotics
Use antibiotics ___ days , not immediately
1-3 days
Routes of injectable antibiotics (3)
IV
IM
SQ
- Nanotechnology/Nanofiber: mimic fibrin clot
- Vacuum technology
- Hydrogels
Novel Techniques
Signs of Wound dehiscence (5)
- Pain
- Swelling
- Tissue necrosis
- Discoloration
- Sero-sangilinous discharge
PRIMARY causes of wound dehiscence
- Necrosis
- Distention
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