19/06 Flashcards
upper vs lower GIB
ligament of Treitz
metastatic bone pain
analgesia
bisphosphonates
radiotherapy
BRCA2 assoc men
prostate cancer
ITP tx
prednisolone
iron deficiency anaemia
hypochromic microcytic anaemia
high TIBC
low ferritin and transferrin
anaemia of chronic disease
low TIBC
low transferrin
high ferritin
ITP invx
antiplatelet autoantibodies (usually IgG)
bone marrow aspiration to rule out leukaemia
decreased haptoglobin
intravascular haemolysis
abdo and neuro signs
blue lines on gums
lead poisoning
ovaries lymph drainage
para-aortic lymphatics via the gonadal vessels
uterine fundus lymph drainage
para-aortic nodes
inguinal nodes
body of uterus lymph drainage
iliac lymph nodes
cervix lymph drainage
external iliac nodes
presacral nodes
internal iliac nodes
methotrexate anaemia
macrocytic megaloblastic
‘chocolate’ cyanosis
Methaemoglobinaemia
myelodysplasia progression
acute myeloid leukaemia (AML)
unobtainable bone marrow biopsy - ‘dry tap’ therefore trephine biopsy needed
myelofibrosis
myeloma imaging
whole body MRI
monoclonal IgM paraproteinaemia
waldenstroms macroglobulinaemia
most common inherited bleeding disorder
vWF
tumour lysis syndrome electrolytes
high potassium
high phosphate
low calcium
clinical features of tumour lysis syndrome
increased serum creatinine
cardiac arrhythmia or sudden death
seizure
essential thrombocytosis mx
hydroxyurea (hydroxycarbamide) is widely used to reduce the platelet count
interferon-α is also used in younger patients
low-dose aspirin may be used to reduce the thrombotic risk
sideroblastic anaemia
deposits of iron in the mitochondria that form a ring around the nucleus called a ring sideroblast
basophilic stippling of red blood cells
ringed sideroblasts
sideroblastic anaemia
sickle cell diagnossi
haemoglobin electrophoresis
long term mx sickle cell
hydroxyurea
sickle cell crisis reduced reticulocyte count
aplastic crisis
sickle cell crisis increased reticulocyte count
sequestration crisis
post thrombotic syndrome tx
compression stockings
polycythaemia vera mx
aspirin
venesection
hydroxyurea
when to offer a platelet transfusion
count <30 if active bleeding
count <10 if no active bleeding or planned procedure
highest risk of bacterial contamination blood product
platelets
patients with acute, severe, symptomatic hyponatraemia (< 120 mmol/L)
hypertonic saline (3%)
stress incontinence
duloxetine
?angina invx
Contrast-enhanced CT coronary angiogram
when should abx be given in AOM
> 4 days or not improving
Systemically unwell but not requiring admission
Immunocompromised or high risk of complications
< 2 years old with bilateral otitis media
Otitis media with perforation and/or discharge in the canal
sinusitis symptoms >10 days
intranasal steroids
most common cause tonsilitis
strep pyogenes
what does everything need to be above for a normal audiogram
20dB line
+ve dixhallpike manouvre BPPPV
rotatory nystagmus
neck lump anterior and lateral to SCM muscle
branchial cyst
foul-smelling, non-resolving discharge
cholesteatoma
chronic sinusitis mx
avoid allergen
intranasal corticosteroids
nasal irrigation with saline solution
bilateral high-frequency hearing loss
presbycusis
‘flamingo tinge’ tympanic membrane
otosclerosis
ototoxic drugs
aminoglycosides eg gent
furosemide
aspirin
ear wax tx
ear syringing and ear drops
olive oil
sodium bicarbonate 5%
almond oil
mx of epistaxis
pinch soft part of nose and lean forward for 20 mins
naseptin (unless peanut soy or neomycin allergy)
cautery if bleed is visible
nasal packing
ligation of the sphenopalantine artery in theatre
gingival hyperplasia drug causes
phenytoin
ciclosporin
calcium channel blockers
gingivitis mx (before dentist)
oral metronidazole for 3 days
chlorhexidine or hydrogen peroxide mouth wash
simple analgesia
tx of glue ear
grommets
adenoidectomy
ludwigs angina
progressive cellulitis that invades the floor of the mouth and soft tissues of the neck
tx - IV abx and airway mx
malignant otitis externa biggest RF
diabetes