19/06 Flashcards
upper vs lower GIB
ligament of Treitz
metastatic bone pain
analgesia
bisphosphonates
radiotherapy
BRCA2 assoc men
prostate cancer
ITP tx
prednisolone
iron deficiency anaemia
hypochromic microcytic anaemia
high TIBC
low ferritin and transferrin
anaemia of chronic disease
low TIBC
low transferrin
high ferritin
ITP invx
antiplatelet autoantibodies (usually IgG)
bone marrow aspiration to rule out leukaemia
decreased haptoglobin
intravascular haemolysis
abdo and neuro signs
blue lines on gums
lead poisoning
ovaries lymph drainage
para-aortic lymphatics via the gonadal vessels
uterine fundus lymph drainage
para-aortic nodes
inguinal nodes
body of uterus lymph drainage
iliac lymph nodes
cervix lymph drainage
external iliac nodes
presacral nodes
internal iliac nodes
methotrexate anaemia
macrocytic megaloblastic
‘chocolate’ cyanosis
Methaemoglobinaemia
myelodysplasia progression
acute myeloid leukaemia (AML)
unobtainable bone marrow biopsy - ‘dry tap’ therefore trephine biopsy needed
myelofibrosis
myeloma imaging
whole body MRI
monoclonal IgM paraproteinaemia
waldenstroms macroglobulinaemia
most common inherited bleeding disorder
vWF
tumour lysis syndrome electrolytes
high potassium
high phosphate
low calcium
clinical features of tumour lysis syndrome
increased serum creatinine
cardiac arrhythmia or sudden death
seizure
essential thrombocytosis mx
hydroxyurea (hydroxycarbamide) is widely used to reduce the platelet count
interferon-α is also used in younger patients
low-dose aspirin may be used to reduce the thrombotic risk
sideroblastic anaemia
deposits of iron in the mitochondria that form a ring around the nucleus called a ring sideroblast
basophilic stippling of red blood cells
ringed sideroblasts
sideroblastic anaemia
sickle cell diagnossi
haemoglobin electrophoresis
long term mx sickle cell
hydroxyurea
sickle cell crisis reduced reticulocyte count
aplastic crisis
sickle cell crisis increased reticulocyte count
sequestration crisis
post thrombotic syndrome tx
compression stockings
polycythaemia vera mx
aspirin
venesection
hydroxyurea
when to offer a platelet transfusion
count <30 if active bleeding
count <10 if no active bleeding or planned procedure
highest risk of bacterial contamination blood product
platelets
patients with acute, severe, symptomatic hyponatraemia (< 120 mmol/L)
hypertonic saline (3%)
stress incontinence
duloxetine
?angina invx
Contrast-enhanced CT coronary angiogram
when should abx be given in AOM
> 4 days or not improving
Systemically unwell but not requiring admission
Immunocompromised or high risk of complications
< 2 years old with bilateral otitis media
Otitis media with perforation and/or discharge in the canal
sinusitis symptoms >10 days
intranasal steroids
most common cause tonsilitis
strep pyogenes
what does everything need to be above for a normal audiogram
20dB line
+ve dixhallpike manouvre BPPPV
rotatory nystagmus
neck lump anterior and lateral to SCM muscle
branchial cyst
foul-smelling, non-resolving discharge
cholesteatoma
chronic sinusitis mx
avoid allergen
intranasal corticosteroids
nasal irrigation with saline solution
bilateral high-frequency hearing loss
presbycusis
‘flamingo tinge’ tympanic membrane
otosclerosis
ototoxic drugs
aminoglycosides eg gent
furosemide
aspirin
ear wax tx
ear syringing and ear drops
olive oil
sodium bicarbonate 5%
almond oil
mx of epistaxis
pinch soft part of nose and lean forward for 20 mins
naseptin (unless peanut soy or neomycin allergy)
cautery if bleed is visible
nasal packing
ligation of the sphenopalantine artery in theatre
gingival hyperplasia drug causes
phenytoin
ciclosporin
calcium channel blockers
gingivitis mx (before dentist)
oral metronidazole for 3 days
chlorhexidine or hydrogen peroxide mouth wash
simple analgesia
tx of glue ear
grommets
adenoidectomy
ludwigs angina
progressive cellulitis that invades the floor of the mouth and soft tissues of the neck
tx - IV abx and airway mx
malignant otitis externa biggest RF
diabetes
malignant otitis externa cause
Pseudomonas aeruginosa
acute attacks menieres
buccal or intramuscular prochlorperazine
prevention menieres
betahistine and vestibular rehabilitation exercises
nasal polyps mx
refer to ENT
topical steroids can shrink size
Unilateral serous otitis media
?nasopharyngeal carcinoma
nasopharyngeal carcinoma mx
radiotherapy
otitis externa tx
topical antibiotic or a combined topical antibiotic with a steroid
pleomorphic adenoma tx
surgical excision
ramsay hunt syndrome tx
oral aciclovir and corticosteroids
horizontal nystagmus
vestibular neuronitis
vestibular neuronitis/vestibular neuronitis drug tx
prochlorperizene or an antihistamine
what meds should be stopped in c diff
opiods
raised AFP and HCG
non-seminomatous testicular cancer
murmur turners syndrome
bicupsid aortic valve - ejection systolic murmur
H pylori test post eradication
urea breath test
rectal tumours
anterior resection
complication of fluid resus in young pt DKA
cerebral oedema
where can a gallstone block that does NOT cause jaundice
cystic duct
medical mx of a miscarriage
vaginal misoprostol
symptoms of mania in primary care
URGENT referral to CMHT
symptoms of hypomania in primary care
ROUTINE referral to CMHT
bilous vomiting first day
intestinal atresia
medical abortion
mifepristone followed by prostaglandins
GBS prophylaxis
benzypenicillin
drug that can precipitate digoxin toxicity
thiazides eg indapamide
cushings biochem abnormality
hypokalaemic metabolic alkalosis
anaphylactoid reaction to Nacetylcysteine
stop infusion and consider at a slower rate
if at the time of diagnosis of GDM, the fasting glucose level is >= 7 mmol/l
insulin
long saphenous vein superficial thrombophlebitis
USS to exclude DVT
IM B12
IM hydroxocobalamin
oral codeine to morphine
divide by 10
symptom control in bronchiectasis
inspiratory muscle training + postural drainage
severe flare UC tx
IV steroids
AACG predisposing factors
hypermetropia (long-sightedness)
pupillary dilatation
lens growth associated with age
AACG invx
tonometry
gonioscopy
AACG definitive mx
laser peripheral iridotomy
DRY ARMD
drusen
wet ARMD
choroidal re-vascularisation
dry ARMD tx
zinc with anti-oxidant vitamins A,C and E
wet ARMD tx
anti-VEGF
HLAB27 aka ank spond
eye
anterior uveitis
cataracts old age
nuclear
cataracts steroid use
subscapular
proliferative diabetic retinopathy
pre-proliferative diabetic retinopathy
DIABETIC RETINOPATHY TX
panretinal laser photocoagulation
intravitreal VEGF injections
IBD, rheumatoid arthritis
eye
episcleritis
not painful red eye with mobile injected vessels
episcleritis
dendritic corneal ulcer
herpes simplex keratitis
herpes zoster ophthalmicus tx
oral antiviral treatment for 7-10 days
holmes adie pupil
dilated
Anhidrosis of the face, arm and trunk
Stroke
Syringomyelia
Multiple sclerosis
Tumour
Encephalitis
Anhidrosis of the face
Pancoast’s tumour
Thyroidectomy
Trauma
Cervical rib
No anhidrosis
Carotid artery dissection
Carotid aneurysm
Cavernous sinus thrombosis
Cluster headache
hypertensive retinopathy
bacterial conjuncitivitis
purulent discharge
viral conjunctivitis
serous discharge
keratitis contact lens user
Pseudomonas aeruginosa
persistent watery eye in a newborn
nasolacrimal duct obstruction - teach pts to massage duct
orbital cellulitis invx
CT with CONTRAST
sudden appearance of flashes and floaters
posterior vitreous detachment
primary open angle glaucoma tx
selective laser trabeculoplasty
prostaglanding eye drops
peripheral visual field loss
glaucoma
Dense shadow that starts peripherally progresses towards the central vision
retinal detachment
uncorrected squint leads to
amblyopia
painful red eye
scleritis
night blindness and tunnel vision
Retinitis pigmentosa
retinal detachment sight RF
myopia
small, fixed oval pupil, ciliary flush
anterior uveitis
Investigating suspected PE: if the CTPA is negative
consider a proximal leg vein ultrasound scan if DVT is suspected
cannot get above the swelling
inguinal hernia
can get above the swelling
hydrocele
LP finding guillan barre
elevated protein with normal white cell count
indapamine
thiazide
mild-moderate flare of distal ulcerative colitis
rectal aminosalicylates
secondary prevention post MI
ACEi
Beta Blocker
Cholesterol lowering agent (Statin)
Dual antiplatelet therapy
pyloric stenosis
Hypochloremic, hypokalaemic metabolic alkalosis
cytotoxic agent pulmonary fibrosis
bleomycin
lynch syndrome/HNPCC
development of bowel cancer (among other cancers) with little formation of adenomatous polyps
when would you thrombolyse in PE
hypotension
small bowel overgrowth syndrome
hydrogen breath test