17-3 Flashcards
What are the 5 types of WBC?
1 Neutrophils 2 Eosinophils 3 Basophils 4 Lymphocytes 5 Monocytes
What is included in a CBC?
1 WBC count (WBC) 2 RBC count (RBC) 3 Hemoglobin (Hgb) 4 Hematocrit (Hct) 5 Platelets (Plt)
RBC indices:
Mean corpuscular volume (MCV)
Mean corpuscular hemoglobin (MCH)
Mean corpuscular Hgb concentration (MCHC)
RBC distribution width (RDW)
What does WBC w/ differential give you?
total WBC count
& % by type
WBC w/ differential is used to determine what conditions
infection or leukemia
monitor bone marrow infection
Normal WBC Range:
4.5 - 11.0
Low WBC:
> 2,000
High WBC:
30,000
granular leukocytes
phils
agranular leukocytes
cytes
What is the most abundant type of phagocyte?
Neutrophils
Neutrophils make up what % of WBC?
50 -70%
Bands make up what % of WBC?
0-5%
immature neutrophils are also called
bands
Eosinophils make up what % of WBC?
1-5%
What type of WBC is important in defense against infectious disease?
Neutrophils
What type of WBC acts as an inflammatory response to allergic reactions, asthma, and certain myocardial diseases?
Eosinophils
Which is the least abundant type of WBC?
basophils
Basophils make up what % of WBC?
0-1%
Lymphocytes make up what % of WBC?
20-40%
What is the normal range of lymphocytes?
1.2 - 3.4
Monocytes make up what % of WBC?
1-6%
Which type of WBC is formed in the marrow, transforms into histiocytes or macrophages, and defends against mycobacteria, fungi, protozoa, and viruses?
Monocytes
Normal RBC range Males:
4.5 - 5.9
Normal RBC range Females:
4.5 - 5.1
RBC indices are useful in evaluation of what conditions?
Anemia, polycythemia, and nutritional disorders
What gives an estimate of the average volume size of RBCs?
Mean corpuscular volume
Increase in MCV could mean what?
Vit B12 deficiency or folate deficiency
Decrease in MCV could mean what?
abnormality in Hgb synthesis
MCV Normal range:
76-96
Increase in MCH could indicate?
Vit B12 deficiency or folate deficiency
Decrease in MCH could mean what?
iron deficiency
MCH normal range:
27-32
what gives the amount of hemoglobin per RBC?
MCH
what gives you the average concentration of hemoglobin in a given volume of packed RBCs?
MCHC
Hgb / Hct x 100 =
MCHC
What is the normal range of MCHC?
30-35
What is the main component of RBC?
hemoglobin
what protein transports oxygen and carbon dioxide?
hemoglobin
What provides a direct indication of the oxygen-transport capacity of the blood?
Hgb
Normal range Hgb Males:
14-17.5
Normal range Hgb Females:
12.3 - 15.3
Critically low Hgb:
> 8
What is the ratio of the volume of erythrocytes to whole blood?
Hct
What is low in patients with anemia?
Hgb and Hct
Normal Hct Male:
42-52%
Normal Hct Female:
37-47%
What test is used to determine bleeding disorders, bone marrow diseases, or leukemia?
Platelet count
Normal platelet range:
150k - 400k
Low Plt count:
> 20k
High Plt count:
< 1 million
Low WBC is also called?
Leukopenia
High WBC is also called?
leukocytosis
Low WBC may be due to:
bone marrow deficiency disease of the liver or spleen radiation therapy chemotherapy immune system disease
High WBC may be due to:
Anemia Infectious disease Bacterial disease inflammation leukemia
High neutrophils may indicate?
Bacterial infection
High lymphocytes may indicate?
Viral infection
Increase in neutrophils is also called
neutrophilia
Appearance of band cells in infection is called
Left shift
Atypical lymphocytes are frequently secondary to a viral disease like?
mononucleosis
An increase in eosinophils is also called
eosinophilia
What is typically increased in parasitic infections and allergic disorders?
eosinophils
Hct below normal range is what dx
Anemia
Hct above normal range is what dx
polycythemia
Decreased hemoglobin points to what?
hypochromasia
High platelet count is also called
thrombocytosis
Low platelet count is also called
Thrombocytopenia
What can be caused by stress, infection, splenectomy, trauma, anemia, or cirrhosis?
high platelets
What can be caused by TTP, DIC, leukemia, metastatic disorders?
Low platelets
What 9 things are included in CBC Results:
1 Hct 2 Hgb 3 MCHC 4 WBC 5 Granulocytes 6 % Granulocytes 7 Lymph/mono 8 % Lymph/mono 9 Platelets
Where is the power switch located on the QBC star
rear panel left side
When are you supposed to power off the QBC star?
at the end of the day’s testing
If you need to reprint results you must do so before _____
opening the door
Granulocytes appear what color?
orange-yellow
Lymphocytes/monocytes appear what color?
green
Platelets appear what color?
yellow-orange
The precision plastic float in the QBC star tube does what?
expands the buffy coat layer &
penetrates the red blood cell layer
What is directly measured from the cell layers?
hematocrit, WBC, platelets
You should invert the test tube how many times?
12 to 15 times
Fill the tube up to where?
between the first and second line
You should mix the QBC star tube at least how many times?
4
The tube must be inserted into the QBC star within how many minutes?
15 min
Where do you dispose of QBC star tubes?
biohazard sharps container
Electronic QC values are printed how often?
every 8 hours or when turned on
If you see only dashes on the display screen what does that mean?
values are significantly out of range