16-20 Flashcards
Carrier state
Host develops tolerance to pathogens
-results in commensalism since microbes goal is to not kill host
True or false: microbes goal is to kill host
False microbes goal is to not kill host it wants to survive
What are the 2 categories of vaccines
- Prophylactic
- Therapeutic
Prophylactic vaccine
Preventative
-administered before infection
Therapeutic vaccine
Treatment
-administered after infection
What is herd immunity
% of people that need to be vaccinated
What are the 5 types of vaccines
- DNA and RNA
- Live attenuated
- inactivated
- Subunit
- Viral vector
Which is the most effective vaccine and why?
Live attenuated
-closest to pathogen immune response
-causes most side effects
Which is the least effective vaccine
-subunit viral vector
-need booster shots
Which vaccines use the whole virus?
Live attenuated and inactivated
What is autoimmunity and what causes it?
Reaction to self molecules
-failure to differentiate between self and non self
What is an allergy and what causes it?
Reaction to innocuous molecules
-failure to differentiate between dangerous non self and innocuous non self
Type I immune response
-IgE
-soluble antigen
-Mast cell activation
-allergic rhinitis
Type II immune response
-IgG
-cell matrix
-complement, phagocytes, NK cells
-drug allergies
Type III immune response
-IgG
-soluble antigen
-complement phagocytes
-serum sickness
