14.4

Question 1

imidazoles

Answer 1

synthetic fungicides that disrupt ergosterol biosynthesis

Question 2

fluconazole

Answer 2

inhibit ergosterol biosynthesis.

Question 3

allylamines

Answer 3

structurally different class of synthetic anti fungal drugs inhibit an early step in ergosterol biosynthesis

Question 4

terbinafine

Answer 4

a type of allylamine

Question 5

polyenes

Answer 5

class of antifungal agents naturally produced

Question 6

amphotericin b

Answer 6

type of polyene

Question 7

artemisinin

Answer 7

water soluble than the natural version

Question 8

ivermectin

Answer 8

binds to glutamate-gated chlorine channels

Question 9

praziquantel

Answer 9

used for the treatment of parasitic tapeworms and liver flukes

Question 10

acyclovir

Answer 10

synthetic analog of the nucleoside guanosine

Question 11

pleconaril

Answer 11

synthetic antiviral under development

Question 12

reverse transcriptase inhibitors

Answer 12

block the early step of converting viral RNA genome into DNA

Question 13

protease inhibitors

Answer 13

block the processing viral proteins and prevent viral maturation

Question 14

integrase inhibitors

Answer 14

block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome

Question 15

fusion inhibitors

Answer 15

prevent the binding of HIV to the host cell coreceptor and the merging of the viral envelope with the host cell membrane