1.3. CHEMISTRY &SYNTHESIS OF DNA Flashcards
AMP
Adenosine monophosphate
ADP
Adenosine diphosphate
ATP
Adenosine triphosphate
Semi-conservative replication
New and old strand of DNA present in 2 molecules of DNA formed
Helicase
Unwinds dsDNA (breaks hydrogen bonds between two strands)
Single-stranded DNA binding proteins
Bonds single stranded DNA preventing unwound strands from joining
Topoisomerase
Prevents supercoiling of DNA as strands unwind
Primase
Synthesizes a short RNA primer required for DNA polymerization
DNA polymerase
Synthesizes daughter strands from parental strands (5’ to 3’ direction)
-> phosphodiester bond formation
DNA ligase
Joins (ligates) Okazaki fragments together to form the lagging strand
- phosphodiester bond formation