13 Flashcards
fixed flexion of DIP and hyperextension of PIP
swan neck deformity
unable to move a swollen index finger cause
tendon sheath infection
what can leflunomide cause
interstitial lung disease (need to be off for 2 years befor pregnancy)
what can sulfasalazine cause
reduced sperm, neutropenia
what can hydroxychoroquine cause
eye problems
what indicates active RA
DAS>5.1
what type of drug is allopurinol
xanthine oxidase inhibitor
what HLA is RA
HLA DR4
what are the 3 zones of the adrenal cortex
outermost-zona glomerulosa=mineralocorticoids eg aldosterone
then zona fasciculara=glucocorticoids
then zona reticularis=sex steroids and glucocorticoids
what is in the adrenal medulla
chromaffin cells which secrete catecholamines
low sodium, high potassium, palmer hyperpigmentation
addisons disease
what is bowens disease and where is it found
SCC in situ, red scaly patch on leg
describe typical features of BCC
pearly border, picket fence, slow growing, non healing ulcer, teleangectasia, these rarely metstasise
where are eccrine glands found
entire body surface except clitoris, labia minora, external ear canal, high density on soles and palms
where are apocrine glands found
in axillae, nipples, labia, glans penis
what is the angle in glaucoma
iridocorneal angle
which canal gets blocked in glaucoma
canal of schlemm
what are the features on fundoscopy for primary open angle glaucoma
optic disc cupping, cup to disc ratio >0.7, optic disc pallor, bayonetting of vessels, cup notching
mid diastolic murmur with tapping, undisplaced apex, best heard left lateral position using bell
mitral stenosis
ejection systolic murmur, radiating to neck
aortic stenosis
systolic murmur radiates to axilla
mitral regurg
best heard when patient sits up, lean forward and fully expires at left side of lower part of sternum
aortic regurgitation
what is tardive dyskinesia
repetitive involuntary purposeless movements, grimacing, sticking tongue out, lip smacking, pursing lips, blinking, may take years to develop
what is acute dystonic reaction
takes hours or days to develop-muscle spasms, treated with acetylcholine inhibitor