12. muscarinic receptors Flashcards
1
Q
Where are M1 found and what response occurs?
A
salivary glands, secretion of saliva
2
Q
Where are M2 found and what response occurs?
A
cardiac atria and conducting tissue.
cardiac slowing and decreased force of contraction
3
Q
Where are M3 found and what response?
A
smooth muscle of gut
increase in motility
4
Q
M1 g protein subtype and second messenger
A
Gq, PIP2
5
Q
M2 g protein subtype and second messenger
A
Gi, adenylate cyclase
6
Q
M3 g protein subtype and second messenger
A
Gq, PIP2
7
Q
3 muscarinic receptor agonists?
A
carbachol, pilocarpine, bethanechol
8
Q
3 different types of anti-cholinesterases
A
alcohols, carbamates, organophosphates
