106 biosci Flashcards
biochemistry is universal
at the molecular level, we would expect to see the same processes on other life forms
Big bang and origin of life
14 bya, primordial universe had H and He condensing to form first generation stars after the big bang. 7 bya fusion produced heavier elements inc C, N and O. Large unstable stars explode in supernovas and dispersed the elements. Second gen stars form solar systems (condensing) incorporating heavier elements.
Origins of both elements and biological molecules
originated from water and condensation of water on earth, simple gaseous molecules, reducing atmospheres and electrical discharges
biological molecules suggest an
evolutionary ancestry of all life on earth
why biopolymers are modular
scaffolding and to produce large unique complex macromolecules by efficiently prefabricate monomers (subunits) to make biopolymers.
H, C, N and O role in early life
favour bond formation/molecules and C is central to this and the formation of complex molecules and the most abundant in biology.
Reducing atmosphere role
Supports bond formation as bonds form more readily.
Na, Mg, K, Ca, P, S and Cl
secondly abundant and good catalysis elements in biology, maintaining fluid balance and muscle contractions.
Role of carbon
the central role of carbon provides versatility, scaffolding and diversity in chemical compounds. They form covalent bonds with other atoms.
Electrical discharge role in life formation
Provides energy for gas and water molecules enough energy to smash together form new bonds.
1953 Miller Urey primordial soup
Experiment to recreate the beginnings of life, with the four components needed which created new molecules and amino acids such as nucleotides (beta alanine, alanine, aspartic acid and glycine).
3/4 classes of macromolecules are biopolymers
they are carbohydrates, nucleic acids and proteins, lipids however dont polymerise but assemble.
All biopolymers link together (polymerise)
through condensation (dehydration).
The monomer and bond type for polysaccharides (sugars)
Monomer: saccharides, and have glycosidic bonds.