10.3 Regulation Of Contraction Flashcards
Majority thickness of heart wall
Myocardium
Lining inside of myocardium/lumen
Endocardium
Epicardium aka
Visceral layer of pericardium (outside layer)
Endocardium has a layer of
Epithelial tissue. Dense irregular connective tissue
Myocardium comprised of
Myocardiocytes
Intercalated discs
Bridges between the cells containing gap junctions (where calcium can pass from cell to cell)
Sino-Atrial node
Can depolarize spontaneously, sets pace 100-110 bpm (kept slower by parasympathetic signal vagal tone)
HR
70-80 beats/min at rest
Systole - contraction
Diastole - expansion
Other pacers of heart
AV node and purkinje fibers
Dense irregular tissue layer separates the atrium from ventricles preventing conduction
Pacemaker cells have what
A particular membrane protein (funny channels, HCN) allowing sodium to leak in constantly
Myocardiocytes have
Prolonged AP and contraction from Ca plateau
ECG
Measure voltage changes in heart,
- P wave = atrial depolarization
- QRS com = ventricular depolarization
- T wave = ventricular repolarization
- Atrial depolarization hidden in QRS