10. Pediatric Immunizations

Question 1

15th century intentional exposure

Answer 1

smallpox

Question 2

small materials from smallpox used to induced virilization

Answer 2

varioliation

Question 3

meningitis, epiglottitis, pneumonia, virtually none now, initial vaccine was polysaccharide

Answer 3

haemophilus influenza type B

Question 4

common childhood illness, chickenpox, complications varicella pneumonia, vaccine massively dropped hospitalizations and deaths

Answer 4

varicella

Question 5

needed to protect communities against disease

Answer 5

herd immunity

Question 6

work by provoking immune response creating immune memory that is stimulated by that antigen

Answer 6

vaccines

Question 7

shed vaccine virus, small risk of reversion, rotavirus, measles, mumps, rubella, varicella, nasal flu

Answer 7

live attenuated vaccine

Question 8

treated and killed, cannot make you sick, injectable influenza, hepatitis A vaccine

Answer 8

killed vaccines

Question 9

toxoids tetanus and diptheria, hepatitis B vaccine recombinant production of HBsAg, and human papillomavirus vaccine

Answer 9

component vaccines

Question 10

created from polypeptide and saccharides on the outsides of viruses/bacteria, pneumococcal, HiB, pertussis

Answer 10

cellular fraction vaccine

Question 11

antigens attached to proteins that stimulate a T cell response, PCV 12, HiB vaccines, meningococcal vaccines

Answer 11

conjugate vaccines

Question 12

mRNA is translated into target protein which stimulates an immune response

Answer 12

mRNA vaccines

Question 13

stimulate active immunity through creation of antibodies

Answer 13

in common to all vaccines

Question 14

what results from just giving antibodies, generally after exposure to infection, rabies, palivizumab for RSV

Answer 14

passive immunity

Question 15

optimized to provide excellent and individual and community

Answer 15

vaccine schedule

Question 16

prevents liver cancer

Answer 16

hepatitis B vaccine

Question 17

creators of the vaccine schedule

Answer 17

advisory committee on immunization practices, american academy of pediatrics committee

Question 18

modification of vaccine schedule is not evidence based and not recommended

Question 19

no such thing as an alternative vaccine schedule

Question 20

current or recent chemotherapy, immune deficiency, babies in the NICU, high dose steroids, history of anaphylaxis with prior doses, recent IVIG, and moderate to severe illness

Answer 20

indications to alter vaccine schedule

Question 21

redness at the site of injection, rash, lump at site, fever, fussiness, malaise, fatigue, syncope

Answer 21

common vaccine adverse effects

Question 22

anaphylaxis, febrile seizures, intussusception, inconsolable crying, Guillan-Barre syndrome

Answer 22

severe adverse effect, not common

Question 23

allows compensation for complications from adminstration

Answer 23

vaccine advere event reporting system VAERS

Question 24

associated with cervical cancer thus warrants vaccination at young age [11]

Answer 24

reasoning to vaccinate children with HPV

Question 25

all children 6 months or older, increased risk of severe influenza disease in children 24 months and under, or with chronic diseases including asthma, diabetes, cancer, given annually, many options including live attenuated nasal vaccines for ages 2+ only, contraindicated in prior allergic reaction to this vaccine, egg allergy is not a contraindication

Answer 25

influenza vaccine

Question 26

database of vaccine records for all Iowan children

Answer 26

immunization registry information system IRIS

Question 27

clean and dress wound, active vaccination 4 doses over 2 weeks, passive protection with antibodies dosed by weight infiltrated into the wound

Answer 27

rabies treatment regimen

Question 28

not present in vaccines anymore except in some flu vaccines

Answer 28

mecurcy and aluminum

Question 29

redacted paper and untrue

Answer 29

vaccines causing autism

Question 30

are a medication, thus risk/benefit conversations are appropriate

Answer 30

vaccine conversations

Question 31

educate, address concerns, document refusal, ongoing discussion, leave the door open

Answer 31

vaccine refusal procedure