10 airway diseases

Question 1

What are the 2 main readings we get from spirometry, what can we make wit the data?

Answer 1

FEV1 and FVC
(FEV1 to FVC ratio)
Flow-volume loop (inhalation bottom)

Question 2

What happens in an asthma attack?

Answer 2

contraciton of smooth muscle
swelling of epithelium
increased mucous production

Question 3

What drug types would we use in asthma cases, what do they target?

Answer 3

B2 agonists, targeting muscle contraction

steroids, targeting inflammation

Question 4

Name 2 types of Beta2 agonists and steroids for asthma treatment

Answer 4

salbutamol/salmeterol

fluticasone/beclamethasone

Question 5

What is one new asthma treatment?

Answer 5

Omaluzimag - anti IgE

Question 6

In COPD, what can oxidants and proteases cause?

Answer 6

parenchymal damage

mucous hypersecretion

Question 7

How might we assess a COPD patient?

Answer 7

sputum production
breathlessness score (MRC dyspneoa score)

Question 8

What genetic dispositino might make people more likely to have COPD?

Answer 8

anti-trypsin deficiency, inhibiting lung protection