10/7/12 Flashcards
What are the 3 mainstay treatments for acute closed-angle glaucoma?
acetazolamide, Pilocarpine, and mannitol
What is pilocarpine? uses?
a muscarinic agonist (M3) used in glaucoma and xerostomia
How does clonidine lower blood pressure?
by activating central alpha-2 receptors
Medullary sponge kidney is charaqcterized by what histopathology? What clinical problem?
cystic dilation of the collecting tubules; recurrent kidney stones
What diuretic would you give to pts w/ medullary sponge kidney and why?
thiazide; reduce Ca++ stone formation
How does ADPKD cause increased BP?
reduced glomerular perfusion –> renin
What disease causes bone erosion and fractures, plt-penia or pancytopenia, and MΦs w/ “crumpled paper” inclusions?
Gaucher’s disease (glucocerebrosidase deficiency)
Which 2nd messenger directly causes the release of intracellular calcium when a Gq receptor is stimulated, as in the activation of an α-1 receptor on a smooth muscle cell?
IP3
What 2nd messenger directly causes the activation of Protein kinase C after the activation of a Gq -coupled receptor?
DAG
Which serovars of Chlamydia trachomatis cause PID and neonatal conjunctivitis?
D-K
Which serovars of Chlamydia trachomatis cause trachoma?
A-C
Which serovars of Chlamydia trachomatis cause lymphogranuloma venereum?
L1-L3
What ligament contains the hepatic portal veins, hepatic artery proper, the common bile duct, and the cystic artery?
hepatoduodenal ligament
The ligamentum teres is the adult remnant of what embryonic structure?
umbilical vein
The right and left gastric arteries lie w/in what ligament that forms a portion of the lesser omentum?
the gastrohepatic ligament
