10/5/12 b

Question 1

Metolazide and idapamide belong to what class of diuretic?

Answer 1

thiazide

Question 2

Pt’s w/ _______ should not be given thiazides (or most diuretics).

Answer 2

sulfonamide allergy

Question 3

Thiazides and other non-K+-sparing diuretics risk what acid-base disturbance.

Answer 3

alkalosis

Question 4

The lacunar variant of Reed-Sternberg cells and collagen fibrils are seen in the histopathology of what disease?

Answer 4

nodular, sclerosing Hodgkin’s lymphoma

Question 5

In what syndrome do you see esophageal webs?

Answer 5

Plummer-Vinson syndrome

Question 6

What is the main Sx of esophageal webs?

Answer 6

selective dysphagia

Question 7

What are the 3 components of Plummer-Vinson syndrome?

Answer 7

atrophic glossitis, esophageal webs, Fe_def anemia

Question 8

What part of the esophagus do esophageal webs usually occur in?

Answer 8

upper 1/3

Question 9

Pts w/ Plummer-Vinson syndrome are at increased risk of developing what serious disease?

Answer 9

squamous cell carcinoma of the esophagus

Question 10

How many molecules of ATP are normally made from 1 molecule of glucose in normal ANAEROBIC respiration?

Answer 10

2

Question 11

How is CNS toxoplasmosis treated?

Answer 11

pyrimethamine and sulfadiazine

Question 12

What is the classic triad of Wiskott-Aldrich Syndrome?

Answer 12

purpura, eczema, and infections w/ bacteria w/ polysaccharide capsules

Question 13

What are the immunoglobulin levels of Wiskpott-Aldrich syndrome?

Answer 13

low IgM, normal IgG, high IgA/IgE

Question 14

What immunodeficiency shows up later in life in Wiskott-Aldrich Syndrome?

Answer 14

T-cell deficiency

Question 15

What immune deficit characterizes cmmon variable immunodeficiency?

Answer 15

humoral deficiency

Question 16

When does common variable immunodeficiency usu. appear?

Answer 16

late teens/early twenties

Question 17

What is the inheritance pattern of Wiskott-Aldrich?

Answer 17

XR

Question 18

What cardiovascular anomaly, other than coarctation of the aorta, is commonly found in women w/ Turner syndrome?

Answer 18

bicuspid aortic valve

Question 19

Autonomic control of vascular tone is entirely controlled by the _______ nervous system.

Answer 19

sympathetic

Question 20

Which CN is stimulated by stretch of the carotid bodies?

Answer 20

CN IX (glossopharyngeal)

Question 21

Which CN is stimulated by the stretch of the aortic baroreceptors?

Answer 21

CN X (vagus)

Question 22

Within what period of time may thrombolytics be administered to the victim of an ischemic stroke?

Answer 22

3 hrs

Question 23

Why is the effect of alteplase limited to the site of thrombotic occlusion?

Answer 23

plasminogen is activated better in the presence of fibrin

Question 24

What is selegeline?

Answer 24

a centrally-acting MAO-I used in Parkinson’s

Question 25

What is the mechanism of action of acyclovir?

Answer 25

gaunosine analog - terminates DNA replication

Question 26

What bone disease is associated w/ celiac sprue?

Answer 26

osteoporosis

Question 27

Ova in the ovaries are arrested in which stage of meosis?

Answer 27

Diplotene stage of Prophase I