002 - Alcohols Flashcards
1
Q
Which alcohol (primary, secondary, tertiary) produce the greatest sedation?
A
tertiary
2
Q
Toxic effect of ethylene glycol?
active metabolite causing that effect?
What compound blocks synth of this compound?
A
nephrotoxicity
oxalic acid
antabuse (disulfiram)
3
Q
Ethylene glycol bind what to injure kidneys?
A
calcium (chelation/ppt)
4
Q
What alcohol can cause blindness?
what metabolite in this causes blindness?
What compound can inhibit the negative effects of these metabolites?
What does this inhibit in the creation of methanol metabolites?
A
methanol
formaldehyde
antizole (methylpyrazole)
alcohol dehydrogenase
5
Q
In a pinch, what replaces antabuse?
A
ethanol (would have to give iv to have it work fast enough)
6
Q
What meatbolites of ethanol contribute to acidosis?
A
formic acid and acetate
